Article
Biochemistry & Molecular Biology
Xiangrong Guo, Leilei Zhou, Jian Xu, Zhiwei Liu, Junxia Liu, Chonghuai Yan
Summary: The study revealed a non-linear association between maternal selenium status and TSH levels, suggesting that low selenium status during pregnancy may be associated with low thyroid function and low birth weight.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
C. Schneider, H. Schuele, C. F. Baum, P. J. Landrigan, S. S. Hawkins
Summary: Using birth certificate data from 50 states and DC, this study examines the associations between prenatal exposure to power plants and birth outcomes, specifically focusing on the effects on different racial/ethnic groups. The findings suggest that exposure to power plants during pregnancy has negative effects on infant health, particularly for infants born to White women.
Article
Endocrinology & Metabolism
Ke Huang, Shuting Si, Ruimin Chen, Chunlin Wang, Shaoke Chen, Yan Liang, Hui Yao, Rongxiu Zheng, Fang Liu, Binyan Cao, Zhe Su, Maimaiti Mireguli, Feihong Luo, Pin Li, Hongwei Du, Min Zhu, Yu Yang, Lanwei Cui, Yunxian Yu, Junfen Fu
Summary: The study in China found that preterm birth increased the risk of childhood T1DM, while high birth weight only affected girls. Early prevention of T1DM may start with prenatal care, and more attention should be paid to children with preterm birth and girls with high birth weight after birth.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Nutrition & Dietetics
Arianne Sweeting, Jovana Mijatovic, Grant D. Brinkworth, Tania P. Markovic, Glynis P. Ross, Jennie Brand-Miller, Teri L. Hernandez
Summary: Recent studies suggest that the optimal carbohydrate intake during pregnancy is in the range of 47-70% of total energy intake. Further research is needed to investigate the effects of low carbohydrate diets on pregnant women and fetal development.
Article
Environmental Sciences
Guilan Xie, Ruiqi Wang, Wenfang Yang, Landi Sun, Mengmeng Xu, Boxing Zhang, Liren Yang, Li Shang, Cuifang Qi, Mei Chun Chung
Summary: This study found an association between prenatal PM2.5 exposure and reduced birth weight and impaired renal function. Each 10 μg/m³ increment in prenatal PM2.5 was associated with decreased birth weight, glomerular filtration rate (GFR), increased blood urea nitrogen (BUN), and increased uric acid (UA). Renal function played a partial role in the relationship between prenatal PM2.5 and birth weight.
Review
Environmental Sciences
Shihao Jin, Shanshan Cui, Jinghan Xu, Xin Zhang
Summary: This meta-analysis examined the relationship between phthalate exposure and birth weight. The results showed that prenatal exposure to mono-n-butyl phthalate and mono-methyl phthalate was negatively associated with birth weight. Subgroup analysis also indicated a negative association between exposure to mono-n-butyl phthalate and birth weight in females.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Endocrinology & Metabolism
Santosh Lamichhane, Partho Sen, Alex M. Dickens, Matilda Krakstrom, Jorma Ilonen, Johanna Lempainen, Heikki Hyoty, Riitta Lahesmaa, Riitta Veijola, Jorma Toppari, Tuulia Hyotylainen, Mikael Knip, Matej Oresic
Summary: Distinct metabolic patterns can differentiate rapid progressors (RP) from slow progressors (SP) in the development of type 1 diabetes. Metabolites mediated by gut microbiome play a key role in distinguishing RP from SP. Identification of specific metabolites and pathways may have implications for delaying the development of type 1 diabetes.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Environmental Sciences
Jing Liu, Yuanmei Chen, Die Liu, Fang Ye, Qi Sun, Qiang Huang, Jing Dong, Tao Pei, Yuan He, Qi Zhang
Summary: To evaluate the relationship between maternal exposure to particulate matter and offspring birth weight, 61 studies involving 34,506,975 singleton live births in 15 countries were analyzed. The results showed that there was a slight increased risk of term low birth weight (TLBW) among full-term births for every increase in interquartile range (IQR) of PM2.5 and PM10 throughout the entire pregnancy, specifically during the second trimester for PM10. However, no significant association was found between TLBW and all births or between low birth weight (LBW) and particulate matter exposure.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Eiji Kawasaki
Summary: Anti-islet autoantibodies are crucial markers for immune-mediated type 1 diabetes (T1D) and slowly progressive T1D (SPIDDM) or latent autoimmune diabetes in adults (LADA). They are used for diagnosis, pathological analysis, and prediction of T1D. Different autoantibodies serve different purposes, such as reflecting insulitis or pancreatic & beta-cell destruction. Combinatorial analysis of these autoantibodies helps diagnose immune-mediated T1D, while a lack of autoantibodies is associated with fulminant T1D. Evaluating the epitopes and subclasses of these autoantibodies aids in distinguishing diabetes-associated from non-diabetes-associated autoantibodies and predicting future insulin deficiency. New advancements in autoantibody assays can improve the accuracy of diagnosis and prediction of autoimmune disorders.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Jieman Lin, Jie Ding, Xuemei Di, Wenqin Sun, Huifen Chen, Hai Zhang
Summary: The abuse of antibiotics in animal husbandry and the subsequent passive exposure to residual antibiotics through food consumption has resulted in significant public health concerns. This study aimed to investigate the potential adverse effects of prenatal antibiotics exposure on fetal growth and development. The findings suggest that prenatal exposure to certain antibiotics may negatively impact fetal growth indicators.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Review
Multidisciplinary Sciences
Anneliese J. S. Flatt, Carla J. Greenbaum, James A. M. Shaw, Michael R. Rickels
Summary: Type 1 diabetes is characterized by loss and dysfunction of pancreatic islet beta cells, leading to insulin deficiency and hyperglycemia. Assessment of beta cell secretory capacity can detect the loss of beta cells during a presymptomatic phase of autoimmune attack. Islet transplantation can restore physiologic reserve capacity for insulin secretion.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2021)
Article
Public, Environmental & Occupational Health
He Zhou, Xiaoli Sun, Yiding Wang, Yufeng Ye, Hanwei Chen, Qingsong Chen, Guanhao He, Jiaqi Wang, Xin Liu, Moran Dong, Dengzhou Chen, Guimin Chen, Lixia Yuan, Jianpeng Xiao, Jianxiong Hu, Weilin Zeng, Zuhua Rong, Qianqian Zhang, Mengya Zhou, Lingchuan Guo, Yanyun Lv, Jingjie Fan, Yudong Pu, Wenjun Ma, Bo Zhang, Tao Liu
Summary: The study found that prenatal exposure to thallium may lead to lower birth weight, and this association may be mediated by decreased placental weight.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Chengyi Zheng, Jiaqi Tian, Lan Ma, Chunjie Ding, Lin Zhang
Summary: Studies have shown that prenatal ozone exposure is associated with an increased risk of adverse pregnancy outcomes, particularly abnormal birth weight. However, the relationship between birth weight and ozone exposure remains inconclusive. This study found that prenatal ozone exposure was weakly linked to birth weight but was associated with a decreased risk of macrosomia.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Jeanie B. Tryggestad, Megan M. Kelsey, Kimberly L. Drews, Steven D. Chernausek, Elia N. Escaname, Elvira Isganaitis, Sarah Macleish, Siripoom Mckay, Jennifer Sprague, Steve Willi
Summary: This study assessed pregnancy outcomes in young women with youth-onset type 2 diabetes and found a high rate of maternal complications related to significant socioeconomic disadvantage. Improving contraception rates and reproductive planning could potentially prevent these serious complications in young mothers and infants.
Article
Endocrinology & Metabolism
Anita M. Nucci, Suvi M. Virtanen, David Cuthbertson, Johnny Ludvigsson, Ulle Einberg, Celine Huot, Luis Castano, Baerbel Aschemeier, Dorothy J. Becker, Mikael Knip, Jeffrey P. Krischer
Summary: In children at genetic risk of type 1 diabetes, being overweight at 2-10 years of age is associated with an increased risk of progression from multiple IA to type 1 diabetes and with the development of type 1 diabetes, but not with the development of IA. Future studies should assess the impact of weight management strategies on these outcomes.
