Article
Psychology, Developmental
Bianca Serio, Robert Kohler, Fengdan Ye, Sarah D. Lichenstein, Sarah W. Yip
Summary: Women are more vulnerable to internalizing disorders. This study explores multidimensional factors associated with sex differences in internalizing symptoms, including sex hormone levels, physical pubertal development, and family conflict. The findings provide a baseline for future research on the endocrine, neurocognitive, and psychosocial factors related to sex differences in internalizing symptoms.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2022)
Article
Psychology, Biological
Szadvari Ivan, Ostatnikova Daniela, Babkova Durdiakova Jaroslava
Summary: Sex differences between males and females appear early in life and have far-reaching effects on various aspects of our physical, psychological, cognitive, and behavioral characteristics. These differences also play a role in individual health and disease susceptibility. This article reviews the biological mechanisms underlying sex differences in brain organization and function, and how these differences manifest in behavioral and psychological traits. The implications of biologically determined variability between males and females for gender-specific healthcare are discussed.
PHYSIOLOGY & BEHAVIOR
(2023)
Article
Behavioral Sciences
Marco Hirnstein, Markus Hausmann
Summary: This commentary rejects the extreme 'sexual dimorphism' concept and emphasizes the importance of sex/gender differences in the brain, highlighting that even small effects can have meaningful behavioral consequences. It suggests that non-binary sex/gender-related factors may better explain individual differences and play important roles in the etiology of mental and neurodevelopmental disorders. The conclusion underscores the significance of the biopsychosocial approach in understanding sex/gender differences in the brain.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Environmental Sciences
Jieyu Liu, Di Gao, Yanhui Li, Xinli Song, Manman Chen, Qi Ma, Xinxin Wang, Mengjie Cui, Tongjun Guo, Li Chen, Yi Zhang, Wen Yuan, Tao Ma, Jianuo Jiang, Yanhui Dong, Zhiyong Zou, Jun Ma
Summary: This study investigated the effects of phthalate esters (PAEs) and sex hormone disruption on early onset of puberty in children. The findings suggest that long-term exposure to PAEs may increase the risk of early puberty onset, working in synergy with estradiol (E2) and in antagonism with testosterone (TT) in boys. Reducing PAEs exposure may promote pubertal health.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Review
Biochemistry & Molecular Biology
Ya-Ting Chang, Yung-Lung Chen, Hong-Yo Kang
Summary: Sex differences play a significant role in cardiovascular and cognitive function, impacting various aspects including pathophysiology, disease onset, symptoms, and severity. Atrial fibrillation (AF) may contribute to vascular cognitive impairment (VCI), with sex hormones potentially serving as therapeutic targets for early intervention.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Qiuyun Gu, Xiaodi Wang, Luyao Xie, Xinyuan Yao, Linxi Qian, Zhiping Yu, Xiuhua Shen
Summary: This study aimed to investigate the potential regulatory pathways of EGCG in preventing obesity-related precocious puberty. The results showed that EGCG could prevent precocious puberty through the NKB/NK3R signaling pathway.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Neurosciences
Rajpreet Chahal, Kristen Delevich, Jaclyn S. Kirshenbaum, Lauren R. Borchers, Tiffany C. Ho, Ian H. Gotlib
Summary: Researchers have found sex differences in white matter maturation during puberty, with males showing a positive association between pubertal stage and fronto-accumbal fiber density, while females did not exhibit this relationship. Additionally, males reported higher reward sensitivity than females, and only males showed a negative association between fronto-accumbal tract FDC and sensitivity to punishment. These findings suggest that there are sex differences in the maturation of the fronto-accumbal tract during puberty, and this may relate to lower punishment sensitivity in adolescent males compared to females.
Article
Engineering, Environmental
Meiping Tian, Yi-Xin Wang, Xiaofei Wang, Heng Wang, Liangpo Liu, Jie Zhang, Bingru Nan, Heqing Shen, Qingyu Huang
Summary: This study reveals that low-dose arsenic exposure has an endocrine disrupting effect on male reproductive health by stimulating Leydig cell steroidogenesis and accelerating urinary steroid excretion. This extends previous knowledge of the inverse association between high-dose arsenic exposure and sexual steroid production, which is believed to be anti-androgen.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Behavioral Sciences
Camille Michele Williams, Hugo Peyre, Roberto Toro, Franck Ramus
Summary: Men and women show significant differences in overall brain size, but once individual differences are taken into account, there is almost no difference in the volume of specific cortical or subcortical structures. Brain differences are mainly attributable to differences in body size.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Endocrinology & Metabolism
Jie Li, Wenting Hao, Chunying Fu, Chengchao Zhou, Dongshan Zhu
Summary: This study found that postmenopausal women are more likely to experience memory impairment compared to men, particularly in objective memory. Female reproductive factors such as age at menarche and menopause may influence the risk of memory problems.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Behavioral Sciences
Aleksandra Kosza Koszalka, Klaudia Lustyk, Karolina Pytka
Summary: This review discusses the recent progress in understanding the biological sex differences in cognition and highlights the challenges encountered in such research. It focuses on spatial, recognition, and emotional memory, as well as executive functions such as attention, cognitive flexibility, and working memory.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Psychology, Developmental
Blythe A. Corbett, Rachael A. Muscatello, Briana K. Horrocks, Mark E. Klemencic, Yasas Tanguturi
Summary: The study found that adolescents with autism spectrum disorder (ASD) had higher BMI percentiles during pre-to-early puberty compared to typically developing youth, indicating a potentially heightened risk for weight-related health concerns.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2021)
Review
Pediatrics
Qianfan Yang, Kameron Kennicott, Runqi Zhu, Jooyong Kim, Hunter Wakefield, Katelyn Studener, Yun Liang
Summary: The majority of autoimmune diseases affect more women than men, indicating the important role of sex hormones in regulating immune response. Current research emphasizes the significance of sex hormones in both immune and metabolic regulation. Puberty is characterized by significant changes in sex hormone levels and metabolism, which may contribute to the difference in autoimmunity bias between men and women.
FRONTIERS IN PEDIATRICS
(2023)
Review
Biochemistry & Molecular Biology
Sara Trova, Serena Bovetti, Sara Bonzano, Silvia De Marchis, Paolo Peretto
Summary: Steroid hormones play important roles in vertebrates, especially in mammalian sexual development and brain neural circuits. Studies in recent decades have shown that sex steroids influence the organization of the brain structure during puberty, a critical period characterized by high sensitivity to external stimuli and significant remodeling of the organism's structure and function.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Physiology
Bethany D. D. Skinner, Samuel R. C. Weaver, Samuel J. E. Lucas, Rebekah A. I. Lucas
Summary: This study compared cerebrovascular-CO2 responsiveness between females in different phases of the menstrual cycle and males, and found that females have enhanced vasoconstrictive capacity of the middle cerebral artery during ovulation and mid-luteal phase, while males have weaker cerebrovascular-CO2 responsiveness.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Health Care Sciences & Services
Shervin Shahnavaz, Erik Hedman-Lagerlof, Tove Hasselblad, Lena Reuterskiold, Viktor Kaldo, Goran Dahllof
JOURNAL OF MEDICAL INTERNET RESEARCH
(2018)
Article
Health Care Sciences & Services
Alexander Miloff, Per Carlbring, William Hamilton, Gerhard Andersson, Lena Reuterskiold, Philip Lindner
JOURNAL OF MEDICAL INTERNET RESEARCH
(2020)
Article
Health Care Sciences & Services
Philip Lindner, Alexander Rozental, Alice Jurell, Lena Reuterskiold, Gerhard Andersson, William Hamilton, Alexander Miloff, Per Carlbring
JMIR SERIOUS GAMES
(2020)
Article
Behavioral Sciences
Liis Burket, Thomas Parling, Markus Jansson-Frojmark, Lotta Reuterskiold, Josefin Ahlqvist, Shervin Shanavazh, Gustaf Reinebo, Bo Vinnars, Maria Beckman, Benjamin Bohman, Alexander Rozenthal, Cornelia Larsson, Annika Lindgren, Johanna Linde, Marianne Bonnert, Tobias Lundgren
Summary: The study developed a questionnaire to measure psychological flexibility in epilepsy, demonstrating satisfactory structure and reliability with moderate correlations to quality of life, psychological flexibility in the general population, depressive symptoms, and anxiety symptoms. The number of seizures was positively correlated with questionnaire scores.
EPILEPSY & BEHAVIOR
(2021)
Article
Psychiatry
Philip Lindner, Peter Dafgard, Alexander Miloff, Gerhard Andersson, Lena Reuterskiold, William Hamilton, Per Carlbring
Summary: Consumer Virtual Reality (VR) technology is a powerful medium for disseminating mental health interventions, VR exposure therapy has been shown to be effective in treating anxiety disorders, and the lowered threshold hypothesis suggests a mechanism for continued improvement.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Developmental
Maria Helander, Martin Asperholm, Dan Wetterborg, Lars-Goran Ost, Clara Hellner, Agneta Herlitz, Pia Enebrink
Summary: This systematic review and meta-analysis evaluated the effects of Parent Management Training (PMT), Parent-Child Interaction Therapy (PCIT), and PMT combined with child cognitive behavioral therapy (CBT) on children with clinical levels of disruptive behavior. The results showed that PMT and PCIT were more effective than waiting-list in reducing disruptive behavior. PMT also improved parental skills and child social skills. PCIT had larger effects in reducing disruptive behavior than PMT. The addition of child CBT to PMT did not yield larger effects than PMT or waiting-list.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2022)
Article
Psychology, Clinical
Alexander Miloff, Philip Lindner, Peter Dafgard, Stefan Deak, Maria Garke, William Hamilton, Julia Heinsoo, Glenn Kristoffersson, Jonas Rafi, Kerstin Sindemark, Jessica Sjolund, Maria Zenger, Lena Reuterskiold, Gerhard Andersson, Per Carlbring
BEHAVIOUR RESEARCH AND THERAPY
(2019)
Article
Psychology, Multidisciplinary
Philip Lindner, Alexander Miloff, Lena Reuterskiold, Gerhard Andersson, Per Carlbring
SCANDINAVIAN JOURNAL OF PSYCHOLOGY
(2019)
Article
Psychology, Multidisciplinary
Philip Lindner, Alexander Miloff, Elin Zetterlund, Lena Reuterskiold, Gerhard Andersson, Per Carlbring
FRONTIERS IN PSYCHOLOGY
(2019)
Article
Psychology, Clinical
Thomas H. Ollendick, Sarah M. Ryan, Nicole N. Capriola-Hall, Lena Reuterskiold, Lars-Goran Ost
BEHAVIOUR RESEARCH AND THERAPY
(2017)
Review
Behavioral Sciences
Philip Lindner, Alexander Miloff, William Hamilton, Lena Reuterskiold, Gerhard Andersson, Mark B. Powers, Per Carlbring
COGNITIVE BEHAVIOUR THERAPY
(2017)
Article
Behavioral Sciences
Ewa Mortberg, Lena Reuterskiold, Maria Tillfors, Tomas Furmark, Lars-Goran Ost
COGNITIVE BEHAVIOUR THERAPY
(2017)
Article
Psychology, Clinical
Thomas H. Ollendick, Lars-Goran Ost, Sarah M. Ryan, Nicole N. Capriola, Lena Reuterskiold
BEHAVIOUR RESEARCH AND THERAPY
(2017)
Article
Psychology, Multidisciplinary
Daniela Weber, Serhiy Dekhtyar, Agneta Herlitz
Article
Behavioral Sciences
Kristin Nordin, Agneta Herlitz, Elna-Marie Larsson, Hedvig Soderlund
BEHAVIOURAL BRAIN RESEARCH
(2017)
