Axonal protein synthesis and the regulation of primary afferent function

A Sensory-Labeled Line for Cold: TRPM8-Expressing Sensory Neurons Define the Cellular Basis for Cold, Cold Pain, and Cooling-Mediated Analgesia

(2013) W. M. Knowlton et al.   JOURNAL OF NEUROSCIENCE

Intra-axonal Synthesis of Eukaryotic Translation Initiation Factors Regulates Local Protein Synthesis and Axon Growth in Rat Sympathetic Neurons

(2013) A. N. Kar et al.   JOURNAL OF NEUROSCIENCE

Peripheral Administration of Translation Inhibitors Reverses Increased Hyperalgesia in a Model of Chronic Pain in the Rat

(2013) Luiz F. Ferrari et al.   JOURNAL OF PAIN

Scratching an itch

(2013) Barbara Namer et al.   NATURE NEUROSCIENCE

mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK

(2013) Ohannes K. Melemedjian et al.   PAIN

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Generation of a Pain Memory in the Primary Afferent Nociceptor Triggered by PKC  Activation of CPEB

(2012) O. Bogen et al.   JOURNAL OF NEUROSCIENCE

Erratum: Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

(2012) Hosung Jung et al.   NATURE REVIEWS NEUROSCIENCE

Insights into the roles of local translation from the axonal transcriptome

(2012) A. Deglincerti et al.   Open Biology

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

(2011) Brian Magnuson et al.   BIOCHEMICAL JOURNAL

Axonal protein synthesis: a potential target for pain relief?

(2011) Ilona Obara et al.   CURRENT OPINION IN PHARMACOLOGY

A Role for Nociceptive, Myelinated Nerve Fibers in Itch Sensation

(2011) M. Ringkamp et al.   JOURNAL OF NEUROSCIENCE

Axonal Localization of Transgene mRNA in Mature PNS and CNS Neurons

(2011) D. E. Willis et al.   JOURNAL OF NEUROSCIENCE

mTOR Kinase Domain Phosphorylation Promotes mTORC1 Signaling, Cell Growth, and Cell Cycle Progression

(2011) B. Ekim et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting Adenosine Monophosphate-Activated Protein Kinase (AMPK) in Preclinical Models Reveals a Potential Mechanism for the Treatment of Neuropathic Pain

(2011) Ohannes K Melemedjian et al.   Molecular Pain

Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice

(2011) Ilona Obara et al.   PAIN

IL-6- and NGF-Induced Rapid Control of Protein Synthesis and Nociceptive Plasticity via Convergent Signaling to the eIF4F Complex

(2010) O. K. Melemedjian et al.   JOURNAL OF NEUROSCIENCE

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

Central mechanisms of pathological pain

(2010) Rohini Kuner   NATURE MEDICINE

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke

(2010) Songlin Li et al.   NATURE NEUROSCIENCE

An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

(2010) Catia Andreassi et al.   NATURE NEUROSCIENCE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Hyperalgesic priming is restricted to isolectin B4-positive nociceptors

(2010) E.K. Joseph et al.   NEUROSCIENCE

Mammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation

(2010) E. Norsted Gregory et al.   NEUROSCIENCE

Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

(2010) L. F. Gumy et al.   RNA

Translating nociceptor sensitivity: the role of axonal protein synthesis in nociceptor physiology

(2009) Theodore J. Price et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

PGE2-induced lasting nociception to heat: Evidences for a selective involvement of A-delta fibres in the hyperpathic component of hyperalgesia

(2009) Lúcia C. Bastos et al.   EUROPEAN JOURNAL OF PAIN

Dynamics of axonal mRNA transport and implications for peripheral nerve regeneration

(2009) Soonmoon Yoo et al.   EXPERIMENTAL NEUROLOGY

A Rapamycin-Sensitive Signaling Pathway Is Essential for the Full Expression of Persistent Pain States

(2009) S. M. Geranton et al.   JOURNAL OF NEUROSCIENCE

Formalin-Induced Behavioural Hypersensitivity and Neuronal Hyperexcitability are Mediated by Rapid Protein Synthesis at the Spinal Level

(2009) Curtis O Asante et al.   Molecular Pain

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

Cellular Basis of Itch Sensation

(2009) Y.-G. Sun et al.   SCIENCE

Translating nociceptive processing into human pain models

(2009) Martin Schmelz   EXPERIMENTAL BRAIN RESEARCH

Visualizing Cold Spots: TRPM8-Expressing Sensory Neurons and Their Projections

(2008) A. Dhaka et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-338 Regulates Local Cytochrome c Oxidase IV mRNA Levels and Oxidative Phosphorylation in the Axons of Sympathetic Neurons

(2008) A. Aschrafi et al.   JOURNAL OF NEUROSCIENCE

Schwann Cell to Axon Transfer of Ribosomes: Toward a Novel Understanding of the Role of Glia in the Nervous System

(2008) F. A. Court et al.   JOURNAL OF NEUROSCIENCE

Proteomic Profiling of Neuromas Reveals Alterations in Protein Composition and Local Protein Synthesis in Hyper-Excitable Nerves

(2008) Hong-Lei Huang et al.   Molecular Pain

Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

(2008) Llewellyn J. Cox et al.   NATURE CELL BIOLOGY

Itch and pain

(2008) Martin Schmelz   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Local Translation in Primary Afferent Fibers Regulates Nociception

(2008) Lydia Jiménez-Díaz et al.   PLoS One