Article
Multidisciplinary Sciences
Amy Keir, Alice Rumbold, Carmel T. Collins, Andrew J. McPhee, Jojy Varghese, Scott Morris, Thomas R. Sullivan, Shalem Leemaqz, Philippa Middleton, Maria Makrides, Karen P. Best
Summary: This study examines infant feeding practices and factors associated with breastfeeding duration in late preterm infants with mothers intending to breastfeed. The results show that 78% of infants received breastmilk as their first feed, but 83% received formula during hospitalisation. While 74% of infants were exclusively breastfed at discharge, the rates dropped to 41% at 6 weeks, 35% at 3 months, and 29% at 6 months corrected age. The use of formula as the first feed was associated with a longer hospital stay and a decrease in exclusive breastfeeding at 6 weeks, while intending to breastfeed for more than 6 months was associated with an increase in exclusive breastfeeding at 6 weeks. The intention to breastfeed for more than 6 months remained an important predictor of exclusive breastfeeding at 3 and 6 months.
Editorial Material
Clinical Neurology
Thiviya Selvanathan, Mireille Guillot, Helen M. Branson, Vann Chau, Edmond N. Kelly, Steven P. Miller
Summary: Malformations of cortical development (MCD) are a rare group of disorders caused by genetic, metabolic, infectious, or vascular factors that disrupt the development of the cerebral cortex. They are typically detected with brain MRI when symptomatic, but recent advances allow for detection during fetal or neonatal periods. This study presents neuroimaging findings and neurodevelopmental outcomes of a very preterm infant with incidentally detected MCD on neonatal research brain MRI.
Article
Pharmacology & Pharmacy
Silvia Iacobelli, Kaeliani Allamele-Moutama, Simon Lorrain, Beatrice Gouyon, Jean-Bernard Gouyon, Francesco Bonsante
Summary: This study aimed to describe the exposure to postnatal corticosteroids (PC) in very preterm infants born at less than 32 weeks of gestation in 41 French tertiary-care NICUs. The study found that 26.1% of the infants were exposed to PC, with systemic and inhaled routes being the most common. The exposure occurred in the first week of life and there were significant variations in exposure rates among different centers.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Pediatrics
Camilla Rigotti, Emanuela Zannin, Giulia Dognini, Raffaele Dellaca, Maria Luisa Ventura
Summary: This study described the trajectory of oscillatory mechanics in infants from the first week of life to term equivalent and evaluated its association with simultaneous lung disease in premature infants. The results showed that oscillatory mechanics parameters were significantly associated with the severity of lung disease.
PEDIATRIC RESEARCH
(2023)
Article
Multidisciplinary Sciences
Tsung-Yu Wu, Wei-Ting Lin, Yen-Ju Chen, Yu-Shan Chang, Chyi-Her Lin, Yuh-Jyh Lin
Summary: This study aimed to improve the definition and prediction of bronchopulmonary dysplasia (BPD) by using machine learning (ML) models to predict respiratory support modalities in preterm infants at 36 weeks' post menstrual age. Data from very-low-birth-weight infants born between 2016 and 2019 were collected, and 24 attributes and 7 ML algorithms were used for analysis. Logistic regression algorithm was found to have the highest accuracy, and simplified models were developed for clinical application.
SCIENTIFIC REPORTS
(2023)
Article
Obstetrics & Gynecology
Ryo Ogawa, Ayaka Kasai, Takehiko Hiroma, Minoru Tozuka, Yuji Inaba, Tomohiko Nakamura
Summary: This study aimed to determine the infection rate, risk, and clinical findings of postnatal CMV infection. It was found that frozen-thawed breast milk feeding is not fully effective in preventing postnatal CMV infection. The prevention of postnatal CMV infection is important to further improve the survival rate of preterm infants.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
(2023)
Article
Nutrition & Dietetics
Xiaotong Wang, Jiajia Jing, Saijun Huang, Xiaoying He, Pingming Gao, Hailin Li, Zongyu Lin, Per Torp Sangild, Yanna Zhu
Summary: Early anemia in very-low-birth-weight (VLBW) preterm infants is negatively correlated with neurodevelopment, especially with behavioral ability, but is not associated with brain injury.
Article
Nutrition & Dietetics
Ching-Min Chang, Ming-Horng Tsai, Wei-Chao Liao, Peng-Hong Yang, Shiao-Wen Li, Shih-Ming Chu, Hsuan-Rong Huang, Ming-Chou Chiang, Jen-Fu Hsu
Summary: This study aimed to investigate the effects of probiotics on the gut microbiota of extremely preterm infants. The results showed that probiotics increased the abundance of Lactobacillus and reduced the duration of total parenteral nutrition. The probiotic group also had a lower rate of late-onset sepsis.
Article
Pediatrics
Caterina Coviello, Serafina Perrone, Giuseppe Buonocore, Simona Negro, Mariangela Longini, Floris Groenendaal, Daniel C. Vijlbrief, Carlo Dani, Manon J. N. L. Benders, Maria Luisa Tataranno
Summary: This study aimed to investigate the relationship between early brain activity and F-2-isoprostanes (IPs) concentrations in preterm newborns. The findings showed that higher plasma IPs levels were associated with decreased functional brain activity on the second day after birth.
Article
Multidisciplinary Sciences
Duan Wang, Li Ming, Yong Zhu
Summary: This study investigates the association between the administration-to-birth interval of antenatal corticosteroids (ACS) and neonatal outcomes in very preterm infants. The results show that an interval of ACS administration greater than 48 hours has significant health promotion effects compared to an interval of less than 48 hours.
Article
Pediatrics
Audrey Marchal, Meggane Melchior, Andre Dufour, Pierrick Poisbeau, Claire Zores, Pierre Kuhn
Summary: This study found that preterm infants are sensitive to sound peaks and light level variations, with a slightly higher sensitivity to sound peaks. Sound peaks and light level variations significantly increased the occurrence of pain behaviors, suggesting a need for further research into the mechanisms behind these behaviors.
Article
Obstetrics & Gynecology
Sudeepta K. Basu, Kushal J. Kapse, Jonathan Murnick, Subechhya Pradhan, Emma Spoehr, Anqing Zhang, Nickie Andescavage, Gustavo Nino, Adre J. du Plessis, Catherine Limperopoulos
Summary: This study investigated the relationship between the severity of bronchopulmonary dysplasia (BPD) and basal-ganglia gamma-aminobutyric acid (GABA+) and glutamate (Glx) concentrations in very preterm (VPT) infants. The results showed that VPT infants with moderate-severe BPD had lower basal-ganglia GABA+ and GABA+/Glx levels, indicating neurophysiological perturbations that could serve as early biomarkers for future cognitive deficits.
EARLY HUMAN DEVELOPMENT
(2023)
Article
Pediatrics
Camilla Rigotti, Emanuela Zannin, Chiara Veneroni, Maria Luisa Ventura, Raffaele L. Dellaca
Summary: This study aims to explore the short-term repeatability of forced oscillation technique (FOT) measurement of lung function, assess the lung function response to bronchodilators (BDs) by FOT, and prove that only some very preterm infants manifest a change in lung mechanics in response to BD. The results suggest a threshold for assessing BD responsiveness by FOT in preterm infants and propose the potential use of FOT in evaluating and personalizing BD treatment.
JOURNAL OF PEDIATRICS
(2022)
Article
Medicine, General & Internal
Elisabeth C. McGowan, Julie A. Hofheimer, T. Michael O'Shea, Howard Kilbride, Brian S. Carter, Jennifer Check, Jennifer Helderman, Charles R. Neal, Steve Pastyrnak, Lynne M. Smith, Marie Camerota, Lynne M. Dansereau, Sheri A. Della Grotta, Barry M. Lester
Summary: This study found that high-risk neonatal neurobehavioral patterns at NICU discharge were associated with adverse cognitive, motor, and behavioral outcomes at 2 years.
Article
Nutrition & Dietetics
Junyan Han, Lan Zhang, Shujuan Li, Yi Zhang, Yuan Jiang, Xiaotian Chen, Yin Wang, Yalan Dou, Ping Dong, Yujing Lv, Yun Cao, Weili Yan
Summary: The study found that macronutrient intakes in the first month of life have impacts on growth and body composition before 6 months of age for very preterm and/or very low birth weight infants. Higher protein intake is associated with better growth and healthier body composition, while higher lipid and carbohydrate intake is associated with higher fat mass and body fat percentage.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
