The building blocks of mammalian lung development

Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways?

(2010) Shailendra R. Singh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Functional Analysis of Two Distinct Bronchiolar Progenitors during Lung Injury and Repair

(2010) Roxana M. Teisanu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development

(2010) Edward E. Morrisey et al.   DEVELOPMENTAL CELL

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

A retinoic acid–dependent network in the foregut controls formation of the mouse lung primordium

(2010) Felicia Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Regeneration and orthotopic transplantation of a bioartificial lung

(2010) Harald C Ott et al.   NATURE MEDICINE

Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung

(2010) J. L. McQualter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-Engineered Lungs for in Vivo Implantation

(2010) T. H. Petersen et al.   SCIENCE

FGF signaling is required for myofibroblast differentiation during alveolar regeneration

(2009) Anne-Karina T. Perl et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Deletion ofPtenExpands Lung Epithelial Progenitor Pools and Confers Resistance to Airway Injury

(2009) Caterina Tiozzo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

β-Catenin Is Not Necessary for Maintenance or Repair of the Bronchiolar Epithelium

(2009) Anna C. Zemke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells

(2009) E. L. Rawlins et al.   DEVELOPMENT

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

(2009) P.-N. Tsao et al.   DEVELOPMENT

Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

(2009) J. S. Guseh et al.   DEVELOPMENT

miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution

(2009) Gianni Carraro et al.   DEVELOPMENTAL BIOLOGY

Foregut separation and tracheo-oesophageal malformations: The role of tracheal outgrowth, dorso-ventral patterning and programmed cell death

(2009) Adonis S. Ioannides et al.   DEVELOPMENTAL BIOLOGY

Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration

(2009) Deborah J. Andrew et al.   DEVELOPMENTAL BIOLOGY

Wnt2/2b and β-Catenin Signaling Are Necessary and Sufficient to Specify Lung Progenitors in the Foregut

(2009) Ashley M. Goss et al.   DEVELOPMENTAL CELL

Conditional gene inactivation reveals roles forFgf10andFgfr2in establishing a normal pattern of epithelial branching in the mouse lung

(2009) Lisa L. Abler et al.   DEVELOPMENTAL DYNAMICS

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

(2009) Ethan David Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of hypoxia and neurogenic genes (Mash-1 and Prox-1) in the developmental programming and maturation of pulmonary neuroendocrine cells in fetal mouse lung

(2009) Suzanne McGovern et al.   LABORATORY INVESTIGATION

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

Stem cells are dispensable for lung homeostasis but restore airways after injury

(2009) A. Giangreco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -Catenin promotes respiratory progenitor identity in mouse foregut

(2009) K. S. Harris-Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GP130-STAT3 Regulates Epithelial Cell Migration and Is Required for Repair of the Bronchiolar Epithelium

(2008) Hiroshi Kida et al.   AMERICAN JOURNAL OF PATHOLOGY

Emerging pulmonary vasculature lacks fate specification

(2008) Margaret A. Schwarz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Longitudinal Evaluation of Airway Function 21 Years after Preterm Birth

(2008) Indra Narang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Platelet-Derived Growth Factor Receptor-Alpha-Expressing Cells Localize to the Alveolar Entry Ring and Have Characteristics of Myofibroblasts During Pulmonary Alveolar Septal Formation

(2008) Stephen E. McGowan et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia

(2008) Pia Nyeng et al.   BMC DEVELOPMENTAL BIOLOGY

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme

(2008) J. Rajagopal et al.   DEVELOPMENT

Mechanisms of TGFβ inhibition of LUNG endodermal morphogenesis: The role of TβRII, Smads, Nkx2.1 and Pten

(2008) Yiming Xing et al.   DEVELOPMENTAL BIOLOGY

An FGF–WNT gene regulatory network controls lung mesenchyme development

(2008) Yongjun Yin et al.   DEVELOPMENTAL BIOLOGY

Centrifugal migration of mesenchymal cells in embryonic lung

(2008) Lin Shan et al.   DEVELOPMENTAL DYNAMICS

Emphysema in young adult survivors of moderate-to-severe bronchopulmonary dysplasia

(2008) P. M. Wong et al.   EUROPEAN RESPIRATORY JOURNAL

Mesodermal Deletion of Transforming Growth Factor-β Receptor II Disrupts Lung Epithelial Morphogenesis

(2008) Min Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical transplantation of a tissue-engineered airway

(2008) Paolo Macchiarini et al.   LANCET

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE

The branching programme of mouse lung development

(2008) Ross J. Metzger et al.   NATURE

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration

(2008) Yuzhen Zhang et al.   NATURE GENETICS

A protocol for unraveling gene regulatory networks

(2008) Stefan C Materna et al.   Nature Protocols

Formation and Differentiation of Multiple Mesenchymal Lineages during Lung Development Is Regulated by β-catenin Signaling

(2008) Stijn P. De Langhe et al.   PLoS One

Global regulatory logic for specification of an embryonic cell lineage

(2008) P. Oliveri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development

(2008) J. Que et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous Fibroblastic Progenitor Cells in the Adult Mouse Lung Are Highly Enriched in the Sca-1 Positive Cell Fraction

(2008) Jonathan L. McQualter et al.   STEM CELLS

Prospective Isolation of Bronchiolar Stem Cells Based Upon Immunophenotypic and Autofluorescence Characteristics

(2008) Roxana M. Teisanu et al.   STEM CELLS

Neoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice

(2007) H. Fehrenbach et al.   EUROPEAN RESPIRATORY JOURNAL

Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway

(2007) Mathieu Unbekandt et al.   MECHANISMS OF DEVELOPMENT