Journal
DEVELOPMENTAL CELL
Volume 22, Issue 1, Pages 1-2Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2011.12.013
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Funding
- NIA NIH HHS [F31 AG034749] Funding Source: Medline
- NIGMS NIH HHS [R01 GM098500] Funding Source: Medline
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Eukaryotic centromeres are propagated by incorporation of the centromere-specific histone CENP-A into centromeric chromatin. Silva et al. (2012) now show that cyclin-dependent kinases (CDKs) hold the CENP-A assembly machinery in an inactive state until mitotic exit and entry into G1, at which time new CENP-A is loaded.
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