4.7 Editorial Material

Protein Evolution in Cell and Tissue Development: Going Beyond Sequence and Transcriptional Analysis

Journal

DEVELOPMENTAL CELL
Volume 21, Issue 1, Pages 32-34

Publisher

CELL PRESS
DOI: 10.1016/j.devcel.2011.06.004

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Funding

  1. NIGMS NIH HHS [R01 GM056169-15, R37 GM035527, R01 GM056169] Funding Source: Medline

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Studies of animal evolution often focus on sequence and transcriptional analysis, based on an assumption that the evolution of development is driven by changes in gene expression. We argue that biochemical and cell biological approaches are also required, because sequence-conserved proteins can have different biochemical, cellular, and developmental properties.

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