Article
Biology
Eric Paulissen, Nicholas J. Palmisano, Joshua S. Waxman, Benjamin L. Martin
Summary: This study reveals the critical role of somite morphogenesis in organizing surrounding tissues to facilitate notochord positioning and angioblast migration, ultimately leading to the formation of a functional cardiovascular system in zebrafish embryos.
Article
Multidisciplinary Sciences
Shelby M. M. Perry, Jeffrey G. G. Whitt, Kelly S. S. Reyna
Summary: This study aims to stage and document the morphological and structural development of California valley quail. The study describes the 43 normal stages of development for California valley quail and compares them with other galliforme species.
Article
Agriculture, Dairy & Animal Science
Mehran Mehri, Shokoufeh Hasanvand, Hossein Bazzi
Summary: The experiment showed that threonine significantly affects the growth of meat-type Japanese quail, with different broken line models indicating a wide range of threonine requirements, and the highest requirement observed for weight gain. Desirability function estimation method was found to be more reliable for predicting threonine requirements.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Samuel V. Rasmussen, Noah E. Berlow, Lisa Hudson Price, Atiya Mansoor, Stefano Cairo, Sandra Rugonyi, Charles Keller
Summary: Preclinical cancer research can be expensive, with in vitro studies often not representative of the tumor microenvironment and mouse studies being costly at scale. Using Japanese quail in chorioallantoic membrane (CAM) assays, researchers have developed a cost-effective method to screen for anti-cancer efficacy and drug toxicity, demonstrating concordance with murine in vivo studies and suggesting potential for validating new anti-cancer agents.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Markus Mittnenzweig, Yoav Mayshar, Saifeng Cheng, Raz Ben-Yair, Ron Hadas, Yoach Rais, Elad Chomsky, Netta Reines, Anna Uzonyi, Lior Lumerman, Aviezer Lifshitz, Zohar Mukamel, Ayelet-Hashahar Orenbuch, Amos Tanay, Yonatan Stelzer
Summary: The mouse embryonic development model provides insights into mammalian cell fate acquisition. Recent studies show that most lineages exhibit combinatorial multifurcation dynamics rather than hierarchical transcriptional transitions.
Article
Agriculture, Dairy & Animal Science
Mahmoud Ghazaghi, Mehran Mehri
Summary: A series of experiments were conducted to determine the phosphorus digestibility in different grains and protein meals for growing Japanese quail. The results showed differences in phosphorus digestibility among different ingredients, with young quail exhibiting higher contribution of endogenous phosphorus when fed with wheat. This study highlights the importance of correcting Apparent Ileal Phosphorus Digestibility (AIDP) and implementing Standardized Ileal Phosphorus Digestibility (SIDP) coefficients in feed formulation.
Review
Biochemistry & Molecular Biology
Nitza Kahane, Chaya Kalcheim
Summary: Multiple processes must operate harmoniously to ensure the proper formation of an embryo, with interactions between cells and tissues regulating cell segregation, specification, growth, and morphogenesis. The formation of the spinal cord and paraxial mesoderm derivatives exemplifies these intricate processes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biology
Yusuke Imoto, Tomonori Nakamura, Emerson G. Escolar, Michio Yoshiwaki, Yoji Kojima, Yukihiro Yabuta, Yoshitaka Katou, Takuya Yamamoto, Yasuaki Hiraoka, Mitinori Saitou
Summary: Single-cell RNA sequencing (scRNA-seq) is a powerful technique in biomedical research, but it is challenging to analyze the high-dimensional and noisy data it produces. In this study, a noise reduction method called RECODE is proposed to address these challenges and improve the analysis of scRNA-seq data. Results show that RECODE consistently resolves the statistical problem known as the curse of dimensionality and outperforms other methods in various analyses.
LIFE SCIENCE ALLIANCE
(2022)
Article
Agriculture, Dairy & Animal Science
Firdevs Korkmaz Turgud, Dogan Narinc
Summary: This study aimed to investigate the effects of adding maca plant powder to the ration at different levels on the growth, slaughter carcass, partial egg production, and reproductive characteristics of Japanese quail. The results showed that adding maca powder increased feed consumption, reduced embryonic deaths, and improved chick quality. However, no positive effects were observed on growth, slaughter carcass, partial egg production, and fertility during the fattening period in Japanese quails.
Article
Multidisciplinary Sciences
Meijiang Gao, Marina Veil, Marcus Rosenblatt, Aileen Julia Riesle, Anna Gebhard, Helge Hass, Lenka Buryanova, Lev Y. Yampolsky, Bjoern Gruening, Sergey Ulianov, Jens Timmer, Daria Onichtchouk
Summary: This study investigates the interaction between pluripotency transcription factors Pou5f3 and Sox19b in zebrafish embryos. The authors find that these factors independently modify chromatin and play roles in regulating gene expression during embryonic development. Loss of Pou5f3 and Sox19b leads to premature expression of genes involved in organogenesis and differentiation.
NATURE COMMUNICATIONS
(2022)
Article
Biology
Shaden Zoabi, Michael Andreyanov, Ronit Heinrich, Shaked Ron, Ido Carmi, Yoram Gutfreund, Shai Berlin
Summary: Researchers developed a custom-made viral vector called AAV1-T593K (AAV1*), which allows efficient transduction and manipulation of quail neurons, expanding the toolkit for avian neuroscience research. By bridging the gap in transduction efficiency between different model organisms, particularly birds, this study facilitates the use of genetically-encoded tools and methods in avian species, advancing the field of avian neuroscience research.
COMMUNICATIONS BIOLOGY
(2023)
Article
Biology
Hinako Kidokoro, Yukio Saijoh, Gary C. Schoenwolf
Summary: Using high-resolution live imaging of zebrafish embryos, this study investigates the cellular dynamics underlying early heart morphogenesis and identifies two key cell behaviors, cell rearrangement and cell shape change, in shaping the heart tube. Left cells exhibit higher activity in these behaviors, driving more rapid convergence of the left primordium and rotation of the heart tube. Loss of Nodal signaling abolishes these asymmetric cell behaviors and convergence of the left and right heart primordia.
COMMUNICATIONS BIOLOGY
(2022)
Article
Plant Sciences
Dan Wang, Miao Qi, Hedi Zhao, Haozhong Wu, Han Chen, Yanan Lan, Yanmin Wang, Yani Jiang, Jingjuan Wang
Summary: The aim of this study was to determine the processing temperatures at which Coptis chinensis Franch. (CC) has the strongest anti-angiogenic effect and to speculate the possible bioactive components. The results showed that CC at different processing temperatures and its seven alkaloids could inhibit angiogenesis, with the most significant effect observed in CC processed at 40 degrees Celsius and palmatine. LC-MS analysis revealed that palmatine displayed the strongest inhibitory effect on angiogenesis. Therefore, this study suggests that the q-CAM model in conjunction with UPLC-MS/MS could be a useful tool for assessing tumor angiogenesis and screening tumor-targeted medicines. Processing temperature can affect the anti-angiogenic effect of CC, and palmatine can be considered as a prospective anti-angiogenic drug.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Microbiology
Nagwa H. Hamouda, W. D. Saleh, N. F. Nasr, M. I. El Sabry
Summary: This study compared the effects of bacterial- and plant-produced silver nanoparticles (Ag-NPs) and TH4 on the microbial load of eggshells and liver structure, embryonic mortality, and hatchability features of quail chicks. The Ag-NPs were synthesized using bacterial and plant methods and were characterized using spectroscopy techniques. The results showed that both B-Ag-NPs and P-Ag-NPs reduced the microbial count on eggshells without affecting hatchability or embryonic mortality. However, the liver structure of chicks treated with Ag-NPs exhibited degeneration of hepatocytes, suggesting potential hazardous effects. TH4 treatment did not cause abnormal liver structure. In conclusion, Ag-NPs can effectively reduce eggshell microbial count, but histological changes should be considered as a safety parameter.
ARCHIVES OF MICROBIOLOGY
(2023)
Article
Developmental Biology
Rebecca K. Schiavo, Owen J. Tamplin
Summary: This study reveals the role of Vegfc in the emergence of HSPCs in the zebrafish dorsal aorta and suggests that it regulates HSPC fate by suppressing a myeloid cell fate.