Article
Biochemistry & Molecular Biology
Li Ping Tang, Yi Yang, Hui Wang, Lixin Li, Le Liu, Yu Liu, Jinfeng Yuan, Xiang Yu Zhao, Klaus Palme, Ying Hua Su, Xugang Li
Summary: AtNSF in Arabidopsis regulates leaf serration by affecting the polar auxin transport mediated by PIN1 and the CUC2 pathway, demonstrating its crucial role in controlling leaf morphology.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2021)
Article
Developmental Biology
Makoto Yanagisawa, Arthur Poitout, Marisa S. Otegui
Summary: Arabidopsis VASCULATURE COMPLEXITY AND CONNECTIVITY (VCC) is a plant-specific transmembrane protein that controls the development of veins in cotyledons. The expression and localization of the auxin efflux carrier PIN-FORMED1 (PIN1) is altered in vcc developing cotyledons, and VCC plays a crucial role in the localization and stability of PIN1 during vascular development.
Editorial Material
Biochemistry & Molecular Biology
Leah R. Band
Summary: The transport through plasmodesmata plays a crucial role in the formation of leaf vein patterns.
Article
Plant Sciences
Irina Kneuper, William Teale, Jonathan Edward Dawson, Ryuji Tsugeki, Eleni Katifori, Klaus Palme, Franck Anicet Ditengou
Summary: This study reveals a synergistic relationship between auxin biosynthesis and cellular auxin efflux in leaf vein development, explaining the formation of midvein morphology through computational modeling. The findings suggest that the site-specific accumulation of auxin, regulated by the balanced action of cellular auxin efflux and local auxin biosynthesis, is crucial for leaf vein formation.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Biochemistry & Molecular Biology
Nguyen Manh Linhi, Enrico Scarpella
Summary: While animal cells form tissue networks through migration and interaction, plant cells lack this ability. However, plants can still form vein networks. This study reveals that vein formation in plants is likely regulated by the movement of the hormone auxin or an auxin-dependent signal through intercellular channels. This mechanism of tissue network formation is unprecedented in multicellular organisms.
Editorial Material
Plant Sciences
Chunmei Guan, Yuling Jiao
Summary: The first step in organ morpho-genesis is the subdivision of a pri-mordium into discrete regions by patterning genes. Recently, Burian et al. used live imaging and cell -lineage tracing to illuminate early patterning events during the es-tablishment of leaf primordium adaxial-abaxial (dorsoventral) po-larity, which clarifies controversies in the field.
TRENDS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Yuta Homma, Mitsunori Fukuda
Summary: The study identified VPS52 as an effector protein responsible for Rab6-dependent secretory cargo trafficking, with its knockout resulting in attenuated secretion and lysosomal accumulation of secretory cargos.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Veronika Bilanovicova, Nikola Rydza, Lilla Koczka, Martin Hess, Elena Feraru, Jiri Friml, Tomasz Nodzynski
Summary: Plant development relies on the redistribution of the hormone auxin between cells, which is facilitated by PIN1 proteins located on the plasma membrane. The hydrophilic loop of PIN1 is intrinsically disordered and plays a crucial role in subcellular trafficking and vasculature formation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Ying-Yi Li, Kazuyuki Kuroki, Tetsuro Shimakami, Kazuhisa Murai, Kazunori Kawaguchi, Takayoshi Shirasaki, Kouki Nio, Saiho Sugimoto, Tomoki Nishikawa, Hikari Okada, Noriaki Orita, Hideo Takayama, Ying Wang, Phuong Doan Thi Bich, Astuya Ishida, Sadahiro Iwabuchi, Shinichi Hashimoto, Takeshi Shimaoka, Noriko Tabata, Miho Watanabe-Takahashi, Kiyotaka Nishikawa, Hiroshi Yanagawa, Motoharu Seiki, Kouji Matsushima, Taro Yamashita, Shuichi Kaneko, Masao Honda
Summary: Through single-cell transcriptome analysis, we have found that DOCK11 plays a crucial role in the persistence of hepatitis B virus (HBV) infection. Our experiments have demonstrated that DOCK11 is functionally associated with the retrograde trafficking process of HBV, helping it avoid lysosomal degradation and maintain covalently closed circular viral DNA (cccDNA). Therefore, DOCK11 is a potential therapeutic target to prevent persistent HBV infection.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Plant Sciences
Zoe Migicovsky, Joel F. Swift, Zachary Helget, Laura L. Klein, Anh Ly, Matthew Maimaitiyiming, Karoline Woodhouse, Anne Fennell, Misha Kwasniewski, Allison J. Miller, Peter Cousins, Daniel H. Chitwood
Summary: This study examined the relationship between leaf lobing and leaf area in grapevine populations. The results showed that lobing was the primary source of shape variation in the leaves, while leaf area was mainly influenced by major vein length, branching vein length, and vein to blade ratio. Highly lobed leaves had longer veins and higher vein to blade ratios, allowing them to maintain similar leaf areas despite increased lobing.
AMERICAN JOURNAL OF BOTANY
(2022)
Article
Biology
Xiaoqin Fu, Lu Rao, Peijun Li, Xinglei Liu, Qi Wang, Alexander Son, Arne Gennerich, Judy Shih-Hwa Liu
Summary: DCX negatively regulates dynein-mediated retrograde transport in neurons through two critical interactions, regulating the binding of dynein to microtubules and the composition of the dynein motor complex.
Article
Biochemistry & Molecular Biology
Raphaelle Luisier, Catia Andreassi, Lisa Fournier, Antonella Riccio
Summary: This study discovered that both NGF and NTF3 affect transcription and alternative polyadenylation in the nucleus and induce the localization of specific 3' UTR isoforms to axons. The integration of the data supports a model where long 3' UTR isoforms associate with RBP complexes in the nucleus and, upon reaching the axons, are remodeled into shorter isoforms. These findings shed new light into the complex relationship between nuclear polyadenylation, mRNA localization, and local 3' UTR remodeling in developing neurons.
Article
Plant Sciences
Daniel H. Chitwood, Joey Mullins, Zoe Migicovsky, Margaret Frank, Robert VanBuren, Jason P. Londo
Summary: The study found that the vein-to-blade ratio in grapevine leaves is an important indicator of leaf size and plasticity, rather than just the area itself. Total precipitation and leaf wetness hours from the previous year showed strong negative correlations with the vein-to-blade ratio, while the maximum air temperature from the previous year was positively correlated.
AMERICAN JOURNAL OF BOTANY
(2021)
Article
Agriculture, Multidisciplinary
Lei Li, Wenzheng Hu, Jiang Lu, Changshui Zhang
Summary: Leaf vein segmentation is an important task that aims to extract vein features and structures. In this study, a novel network model (CoRE-Net) is proposed to enhance segmentation prediction by utilizing the characteristics of leaf veins. Additionally, the first leaf vein dataset is collected and released.
COMPUTERS AND ELECTRONICS IN AGRICULTURE
(2022)
Review
Plant Sciences
Enrico Scarpella
Summary: For multicellular organisms to develop, cells need to grow, divide, and differentiate along specific orientations. In plants, the presence of cell walls prevents cell movements and direct interactions, leading to the evolution of unique mechanisms for coordinating cell axes and polarities. Understanding how leaf veins form may uncover these mechanisms.