Article
Psychiatry
Katarzyna Klasa, Jerzy A. Sobanski, Magdalena Konop, Edyta Dembinska, Michal Mielimaka, Anna Citkowska-Kisielewska, Patrycja Jeda, Magdalena Pelc, Krzysztof Rutkowski
Summary: This retrospective study examines the medical records of 2450 patients with neurotic or personality disorders and finds a significant proportion of these patients reported dyspnea. Additionally, several personality traits were found to be associated with the occurrence of dyspnea and the severity of its burden.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Christina Vesterling, Ute Koglin
Summary: This study aims to examine the interplay of different factors related to childhood somatoform complaints. The results reveal that attachment anxiety and attachment avoidance predict different emotion regulation strategies, which in turn are related to behavior problems and somatoform complaints.
CURRENT PSYCHOLOGY
(2023)
Article
Clinical Neurology
Jared Keeley, Geoffrey M. Reed, Tahilia Rebello, Julia Brechbiel, Jose Angel Garcia-Pacheco, Kazeem Adebayo, Oluyomi Esan, Oluyinka Majekodunmi, Akin Ojagbemi, Lucky Onofa, Rebeca Robles, Chihiro Matsumoto, Maria Elena Medina-Mora, Cary S. Koganl, Maya Kulygina, Wolfgang Gaebel, Min Zhao, Michael C. Roberts, Pratap Sharanr, Jose Luis Ayuso-Mateos, Brigitte Khoury, Dan J. Steinu, Anne M. Lovell, Kathleen Pike, Francis Creedxd, Oye Gureje
Summary: The ICD-11 diagnostic guidelines for Bodily Distress Disorder (BDD) show improvement in clinicians' diagnostic accuracy and perceived clinical utility compared to the guidelines for Somatoform Disorders in ICD-10.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Frederic Maas Genannt Bermpohl, Lea Huelsmann, Alexandra Martin
Summary: This meta-analysis examines the efficacy of third wave psychotherapies (MBCT, MBSR, and ACT) in treating bodily distress. The results show that these therapies are effective in reducing somatic symptom severity, depression and anxiety levels, health anxiety, psychological inflexibility, and improving pain acceptance. Further research is needed to determine which patient groups can benefit from these psychological approaches.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Multidisciplinary
Erine Sokoli, Horst Hildebrandt, Patrick Gomez
Summary: This survey study investigated the various components of music performance anxiety (MPA) and how they are influenced by age, gender, instrument group, musical experience, and practice. The results showed that age, gender, and instrument play a significant role in understanding MPA. The study suggests the importance of assessing musicians based on these characteristics and developing assessment tools that consider the bodily complaints specific to different instrument groups. Furthermore, the high percentage of students reporting a decline in performance quality highlights the need for professional support in helping musicians thrive.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Andreas Hinz, Rueya-Daniela Kocalevent, Heide Glaesmer, Franziska G. Rauscher, Kerstin Wirkner, Regina Treudler, Anja Mehnert-Theuerkauf
Summary: This study analyzed changes in bodily complaints over a six-year period in a large general population. The results showed an overall increase in complaints, with the highest increase observed in sexual pain/problems. Age and socioeconomic status were found to be related to the increase in complaints. The study also found associations between changes in complaints and various health-related variables.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2022)
Article
Engineering, Chemical
Bingru Wang, Long Lin, Shuhang Ren, Weize Wu
Summary: This study measured the specific heat capacities of six ILs and found that the specific heat capacities of ILs increase with temperature regardless of the presence of absorbed SO2. The specific heat capacity of ILs also increases with the amount of absorbed SO2. Additionally, the length of anionic alkyl side chains in ILs affects the specific heat capacity of SO2 absorption.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Article
Biochemical Research Methods
Hai Yang, Rui Chen, Quan Wang, Qiang Wei, Ying Ji, Xue Zhong, Bingshan Li
Summary: This study proposes a multi-label learning-based deep neural network called TVAR to predict the functionality of non-coding variants in the genome based on eQTLs across 49 human tissues. TVAR learns the relationships between high-dimensional epigenomics and eQTLs across tissues, and shows superior performance in predicting functional variants for complex diseases compared with existing tools. The source code and scores of TVAR are available for further use.
Article
Primary Health Care
Bente Kjaer Lyngsoe, Dorte Rytter, Trine Munk-Olsen, Claus Hostrup Vestergaard, Kaj Sparle Christensen, Bodil Hammer Bech
Summary: Maternal depression is associated with daily health complaints and low self-assessed health in the offspring, especially when the mother has continued depression or experiences a relapse. Girls tend to have higher prevalence of mental and somatic health complaints compared to boys.
BRITISH JOURNAL OF GENERAL PRACTICE
(2021)
Article
Family Studies
Christina Vesterling
Summary: The current research on somatoform symptoms in childhood finds that both child and parental factors have an influence. This study aimed to examine the relation and stability between somatoform complaints, children's emotion regulation strategies, withdrawal behavior, and overprotective parenting. The results showed that parental overprotection predicted child emotion regulation, withdrawal behavior, and somatoform complaints over time, but there were no reciprocal effects. Similarly, only unilateral effects were found between adaptive emotion regulation strategies, withdrawal behaviors, and somatoform symptoms. Understanding reciprocal associations is important to comprehend the development of somatoform complaints.
JOURNAL OF CHILD AND FAMILY STUDIES
(2023)
Review
Psychiatry
Mackenzie P. Lerario, Mark Fusunyan, Christopher D. Stave, Valeria Roldan, Alex S. Keuroghlian, Jack Turban, David L. Perez, Tina Maschi, Nicole Rosendale
Summary: The current literature on functional neurological disorder and functional somatic syndromes among sexual and gender minority people is limited. Some studies have reported an increased prevalence of certain conditions among this population. More observational studies are needed to understand the epidemiology and clinical course of functional disorders in sexual and gender minority people.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Psychiatry
Miriam Goebel-Stengel, Ute Paulsen, Petra Bennerscheidt, Stephan Zipfel, Andreas Stengel
Summary: Functional gastrointestinal disorders are common diseases that greatly reduce the quality of life. Good doctor-patient communication is key for successful diagnosis and treatment, but there is limited research on the physicians' perspective.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Hideto Imai, Shingo Haraki, Akiko Tsujisaka, Mutsumi Okura, Hiroyoshi Adachi, Yuko Ohno, Hirofumi Yatani, Takafumi Kato
Summary: The study found that rhythmic masticatory muscle activity (RMMA) and nonspecific masseter activity (NSMA) in sleep bruxism were significantly associated with movements in the leg and arm. There was no significant difference in the relationship between oromotor episodes and bodily movements across different sleep stages.
JOURNAL OF PROSTHODONTIC RESEARCH
(2021)
Article
Medicine, General & Internal
Pascal Cathebras
Summary: This paper emphasizes the need for a patient-centered approach from clinicians when dealing with functional, medically unexplained, or somatoform symptoms and disorders. Patient-centered medicine focuses on the patients' experience of illness, avoids sterile attribution conflicts, and helps doctors and patients collaboratively create plausible and non-stigmatizing explanations for symptoms, paving the way toward effective management.
FRONTIERS IN MEDICINE
(2021)
Article
Multidisciplinary Sciences
Seryan Atasoy, Constanze Hausteiner-Wiehle, Heribert Sattel, Hamimatunissa Johar, Casper Roenneberg, Annette Peters, Karl-Heinz Ladwig, Peter Henningsen
Summary: This study investigated the gender specific risk of all-cause mortality associated with a high somatic symptom burden (SSB). The findings showed that increasing SSB is an independent risk factor for mortality in men, but not in women. This indicates critical gender differences in the management of SSB.
SCIENTIFIC REPORTS
(2022)
Article
Ethics
Christoph Becker, Alessandra Manzelli, Alexander Marti, Hasret Cam, Katharina Beck, Alessia Vincent, Annalena Keller, Stefano Bassetti, Daniel Rikli, Rainer Schaefert, Kai Tisljar, Raoul Sutter, Sabina Hunziker
Summary: The study found a high prevalence of DNR code status among inpatients at the University Hospital of Basel, with a significant proportion of patients choosing full code status despite CPR being considered futile. Presumed CPR futility was closely associated with the decision to refuse resuscitation attempts.
JOURNAL OF MEDICAL ETHICS
(2021)
Article
Gastroenterology & Hepatology
Sabrina Berens, Rainer Schaefert, Johannes C. Ehrenthal, David Baumeister, Annika Gauss, Wolfgang Eich, Jonas Tesarz
Summary: The study compared patients with chronic gastrointestinal complaints with and without somatic symptom disorder (SSD) and found that patients with SSD had higher gastrointestinal pain severity, health and work-related impairment, psychological distress, mentalizing, and personality functioning deficits compared to those without SSD. The results suggest that SSD may be a valid identifier of patients with high psychological burden independent of the medical cause of their symptoms.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2021)
Article
Psychiatry
Alessia Vincent, Katharina Beck, Christoph Becker, Samuel Zumbrunn, Maja Ramin-Wright, Tabita Urben, Adrian Quinto, Rainer Schaefert, Gunther Meinlschmidt, Jens Gaab, Thomas Reinhardt, Stefano Bassetti, Philipp Schuetz, Sabina Hunziker
Summary: COVID-19 is associated with clinically relevant psychological distress in a subgroup of patients and their relatives 90 days after hospital discharge. Understanding potential risk and protective factors may help in developing preventive strategies for this population.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Article
Multidisciplinary Sciences
Katharina Beck, Alessia Vincent, Christoph Becker, Annalena Keller, Hasret Cam, Rainer Schaefert, Thomas Reinhardt, Raoul Sutter, Kai Tisljar, Stefano Bassetti, Philipp Schuetz, Sabina Hunziker
Summary: The study found that a significant number of COVID-19 patients and their relatives experienced psychological distress 30 days after hospital discharge, with factors such as resilience, perceived stress levels, and frequency of contact with relatives being associated with distress. These findings may help in developing strategies to prevent psychological distress in COVID-19 patients and their relatives.
Article
Gastroenterology & Hepatology
Felicitas Engel, Tatjana Stadnitski, Esther Stroe-Kunold, Sabrina Berens, Rainer Schaefert, Beate Wild
Summary: This study found a high correlation between somatic symptoms preceding psychological variables in time, and using positive thoughts as a coping strategy was helpful in reducing pain for the patient with irritable bowel syndrome.
BMC GASTROENTEROLOGY
(2021)
Article
Cell Biology
Sandra Mohr, Nikola Fritz, Christian Hammer, Cristina Martinez, Sabrina Berens, Stefanie Schmitteckert, Verena Wahl, Malin Schmidt, Lesley A. Houghton, Miriam Goebel-Stengel, Maria Kabisch, Dorothea Gotze, Irina Milovac, Mauro D'Amato, Tenghao Zheng, Ralph Roth, Hubert Monnikes, Felicitas Engel, Annika Gauss, Jonas Tesarz, Martin Raithel, Viola Andresen, Thomas Frieling, Jutta Keller, Christian Pehl, Christoph Stein-Thoringer, Gerard Clarke, Paul J. Kennedy, John F. Cryan, Timothy G. Dinan, Eamonn M. M. Quigley, Robin Spiller, Caroll Beltran, Ana Maria Madrid, Veronica Torres, Edith Perez de Arce, Wolfgang Herzog, Emeran A. Mayer, Gregory Sayuk, Maria Gazouli, George Karamanolis, Lejla Kapur-Pojskic, Mariona Bustamante, Raquel Rabionet, Xavier Estivil, Andre Franke, Wolfgang Lieb, Guy Boeckxstaens, Mira M. Wouters, Magnus Simren, Gudrun A. Rappold, Maria Vicario, Javier Santos, Rainer Schaefert, Justo Lorenzo-Bermejo, Beate Niesler
Summary: This study identified genetic single nucleotide polymorphisms (SNPs) associated with irritable bowel syndrome (IBS), particularly with constipation-predominant IBS (IBS-C) in females. Validation in patients and controls from eight countries confirmed the association of the tagging SNP rs2020938 with female IBS-C. Further experiments demonstrated the functional relevance of rs2020938 in differential SLC6A4 expression in the jejunum and stool consistency.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Felicitas Engel, Sabrina Berens, Annika Gauss, Rainer Schaefert, Wolfgang Eich, Jonas Tesarz
Summary: The study found that patients with CD/UC have higher levels of depression and anxiety compared to HC, and there are differences in personality functioning in the domain of self-perception and regulation. Minor differences were found in mentalization and attachment between CD/UC and HC.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Clinical Neurology
Frank Petzke, Thomas Toelle, Mary-Ann Fitzcharles, Winfried Haeuser
Summary: Neuropathic pain is a challenging condition with current medications providing inadequate relief, leading to the consideration of cannabis-based medicines as a treatment option. However, the evidence supporting the use of cannabis-based medicines for chronic neuropathic pain is of low quality, with conflicting conclusions on their efficacy and potential side effects, indicating the need for further research.
Review
Pharmacology & Pharmacy
Mary-Ann Fitzcharles, Frank Petzke, Thomas R. Toelle, Winfried Hauser
Summary: Nociplastic pain is characterized by sensitization of the nervous system without a clear anatomical abnormality to explain the pain severity. It is often associated with central nervous system symptoms such as fatigue, cognitive difficulties, and sleep disturbances, as well as other somatic symptoms. The use of cannabinoids, including cannabis-based medicines, for treating nociplastic pain conditions is a potential avenue that warrants further investigation and understanding by healthcare providers.
Editorial Material
Anesthesiology
Winfried Haeuser, Mary-Ann Fitzcharles
EUROPEAN JOURNAL OF PAIN
(2022)
Review
Anesthesiology
Patric Bialas, Mary-Ann Fitzcharles, Petra Klose, Winfried Haeuser
Summary: This systematic review evaluated the effectiveness, tolerability, and safety of cannabis-based medicines (CbMs) for chronic non-cancer pain (CNCP) in long-term observational studies. The results showed that CbMs had positive effects on multiple symptoms for some CNCP patients and were generally well tolerated and safe. However, the certainty of evidence in observational studies was very low.
EUROPEAN JOURNAL OF PAIN
(2022)
Article
Anesthesiology
Patric Bialas, Claudia Boettge-Wolpers, Mary-Ann Fitzcharles, Sven Gottschling, Dieter Konietzke, Stephanie Juckenhoefel, Albrecht Madlinger, Patrick Welsch, Winfried Haeuser
Summary: There are concerns about the development of cannabis use disorder (CUD) in patients using medical cannabis for chronic pain. The current diagnostic criteria for CUD may not accurately identify patients using cannabis for therapeutic reasons. Alternative strategies are needed to determine the true prevalence of CUD in chronic pain patients treated with medical cannabis. In a study conducted in three German pain centers, the prevalence of CUD in chronic pain patients prescribed medical cannabis was assessed using anonymous questionnaires.
Article
Rheumatology
Ana Margarida Pinto, Rinie Geenen, Tor D. Wager, Mark A. Lumley, Winfried Hauser, Eva Kosek, Jacob N. Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, Joao Castelhano, Miguel Castelo-Branco, Leslie J. Crofford, Mary-Ann Fitzcharles, Marina Lopez-Sola, Mariana Luis, Tiago Reis Marques, Philip J. Mease, Filipe Palavra, Jamie L. Rhudy, Lucina Q. Uddin, Paula Castilho, Johannes W. G. Jacobs, Jose A. P. da Silva
Summary: This article presents a new model called FITSS (Fibromyalgia: Imbalance of Threat and Soothing Systems), which proposes that an imbalance in emotion regulation, specifically an overactive 'threat' system and underactive 'soothing' system, may contribute to the development of fibromyalgia. This model provides a new perspective for future research and may stimulate the discovery of novel therapeutic interventions.
NATURE REVIEWS RHEUMATOLOGY
(2023)
Article
Psychiatry
G. Meinlschmidt, S. Guemghar, N. Roemmel, E. Battegay, S. Hunziker, R. Schaefert
Summary: The study found that depressive symptoms were associated with an increased risk of COVID-19 diagnosis, while anxiety symptoms did not predict COVID-19. Depressive symptoms predicted the likelihood of being tested for SARS-CoV-2, but did not predict COVID-19 in those tested.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2022)
Article
Psychology, Multidisciplinary
Sabrina Berens, Rainer Schaefert, Johannes C. Ehrenthal, David Baumeister, Wolfgang Eich, Jonas Tesarz
Summary: Deficits in affective processing were found in patients with Irritable Bowel Syndrome (IBS) compared to healthy controls (HCs) across six different dimensions, with the most pronounced deficits in affect tolerance. Affective processing in IBS was significantly influenced by anxiety levels and insecure attachment styles, highlighting potential targets for specific psychotherapeutic interventions.
FRONTIERS IN PSYCHOLOGY
(2021)