4.7 Article

P-Arylation of Dialkyl Phosphites and Secondary Phosphine Oxides with Arynes

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 81, Issue 1, Pages 276-281

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.5b02308

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Funding

  1. National Natural Science Foundation of China [21242002]
  2. 100 Young Talents Programme of Guangdong University of Technology [220413506]

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The novel P-arylation of dialkyl phosphites and secondary phosphine oxides with arynes has been achieved. The reactions produce dialkyl arylphosphonates in 71-99% yield and tertiary phosphine oxides in 68-92% yield under mild conditions.

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