Article
Multidisciplinary Sciences
Anne L. Potzel, Christina Gar, Friederike Banning, Vanessa Sacco, Andreas Fritsche, Louise Fritsche, Karsten Muessig, Laura Dauben, Jochen Seissler, Andreas Lechner
Summary: This study tested whether a smartphone-delivered intervention called TRIANGLE is accepted by women after gestational diabetes mellitus (GDM) and alters cardiometabolic risk behaviors and outcomes. The results did not show the efficacy of the TRIANGLE intervention, but the app was well accepted and considered helpful by most users.
Article
Medicine, General & Internal
Moscho Michalopoulou, Susan A. Jebb, Lucy H. MacKillop, Pamela Dyson, Jane E. Hirst, Amy Wire, Nerys M. Astbury
Summary: This study aims to explore the feasibility of a moderately reduced-carbohydrate dietary intervention delivered from mid-pregnancy alongside routine antenatal care.
Article
Multidisciplinary Sciences
Judith Parsons, Rita Forde, Anna Brackenridge, Katharine F. Hunt, Khalida Ismail, Trevor Murrells, Anna Reid, Helen Rogers, Rebecca Rogers, Angus Forbes
Summary: This study assessed the feasibility of an ante- and post-natal lifestyle intervention for women with gestational diabetes mellitus (GDM) to reduce type 2 diabetes risk. The findings suggest that the intervention can support weight loss in women with GDM, with higher rates of weight loss observed in those who preferred the intervention.
Article
Oncology
Shan Xu, Qin Yu, Jiayi Mi, Hua Li
Summary: Nutritional diet therapy can improve the clinical effect of gestational diabetes mellitus (GDM) by reducing complications, controlling blood sugar, and improving neonatal outcomes.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Bernice Man, Alan Schwartz, Oksana Pugach, Yinglin Xia, Ben Gerber
Summary: A clinical prediction model was developed for personalized treatment decisions for prediabetes in women with a history of gestational diabetes mellitus. The study found that higher levels of fasting glucose and hemoglobin A1C were associated with an increased risk of developing diabetes, and metformin was more effective for individuals with higher BMI.
Article
Computer Science, Artificial Intelligence
Nora El-Rashidy, Nesma E. ElSayed, Amir El-Ghamry, Fatma M. Talaat
Summary: The study proposes a framework for predicting gestational diabetes (GDM) during pregnancy, which includes IoT layer, fog layer, and cloud layer. The main contribution of the research is the GDM module implemented in the fog layer, which can replace unused data and predict the occurrence of GDM. By evaluating the data of 16,354 pregnant women, it is found that the prediction model performs better than existing technologies.
Article
Multidisciplinary Sciences
Ling-Wei Chen, Shu E. Soh, Mya-Thway Tint, See Ling Loy, Fabian Yap, Kok Hian Tan, Yung Seng Lee, Lynette Pei-Chi Shek, Keith M. Godfrey, Peter D. Gluckman, Johan G. Eriksson, Yap-Seng Chong, Shiao-Yng Chan
Summary: Women with gestational diabetes mellitus (GDM) have a higher risk of developing type 2 diabetes and dysglycaemia 4-6 years after delivery. Pre-pregnancy overweight and obesity, as well as substantial post-delivery weight retention, exacerbate the risk of post-delivery dysglycaemia, while gestational weight gain does not consistently predict later dysglycaemia risk. Weight management before and after delivery may be crucial for long-term health, especially in women with GDM.
SCIENTIFIC REPORTS
(2021)
Review
Nutrition & Dietetics
Zhi Li, Simian Li, Ying Xiao, Tian Zhong, Xi Yu, Ling Wang
Summary: The combined disease burden of diabetes mellitus (DM) and Alzheimer's disease (AD) is increasing, and there are common pathological changes between the two diseases. The pharmacotherapeutic approach is limited to symptom relief, and the potential of nutritional intervention to extend or synergize with the effects of metformin is being explored. Dietary patterns with an emphasis on diversity have been shown to affect cognitive function and are of interest in various cultural settings. This paper reviews the association between diabetes and AD, as well as cross-cultural nutritional intervention programs that can potentially mitigate both insulin resistance and hyperglycemia, along with cognitive impairment. Both dietary patterns and nutritional supplementation have shown potential effects in improving glycemic control and reducing cognitive decline in diabetes associated with AD, but the specificity of the interventions remains controversial. Multi-nutrient supplements combined with diverse diets may have preventive and therapeutic potential for DM combined with AD, particularly in relation to B vitamins and folate-dependent homocysteine. Nutritional intervention shows promise in preventing and managing the comorbidities of DM and AD, and more clinical studies are needed for further scientific exploration.
FRONTIERS IN NUTRITION
(2022)
Article
Nursing
Ying Jin, Zhengfei Chen, Junqin Li, Wei Zhang, Suwen Feng
Summary: The original Gymnastics for Pregnant Women program significantly improves blood glucose control in women with gestational diabetes mellitus during pregnancy and postpartum. The experimental group showed better blood glucose control, but no statistical differences were observed in maternal or neonatal outcomes.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Endocrinology & Metabolism
Melanie Lloyd, Jedidiah Morton, Helena Teede, Clara Marquina, Dina Abushanab, Dianna J. Magliano, Emily J. Callander, Zanfina Ademi
Summary: The aim of this study was to determine the long-term cost-effectiveness and return on investment of implementing a structured lifestyle intervention to reduce excessive gestational weight gain and associated incidence of gestational diabetes mellitus (GDM) and type 2 diabetes mellitus. The results showed that the intervention was cost-saving compared with usual care from a healthcare perspective, with a return on investment of AU$1.22 per dollar invested. These findings demonstrate significant cost savings and improved health outcomes for women during pregnancy and over their lifetime.
Article
Endocrinology & Metabolism
Ana Ramos-Levi, Ana Barabash, Johanna Valerio, Nuria Garcia de la Torre, Leire Mendizabal, Mirella Zulueta, Maria Paz de Miguel, Angel Diaz, Alejandra Duran, Cristina Familiar, Ines Jimenez, Laura Del Valle, Veronica Melero, Inmaculada Moraga, Miguel A. Herraiz, Maria Jose Torrejon, Maddi Arregi, Laureano Simon, Miguel A. Rubio, Alfonso L. Calle-Pascual
Summary: This study identified a core set of SNPs associated with diabetes and GDM in a large cohort of patients from two main ethnicities. The identification of these genetic variants, even in the context of a nutritional intervention, is useful for designing preventive and therapeutic strategies.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Georgios Tsironikos, Konstantinos Perivoliotis, Alexandra Bargiota, Elias Zintzaras, Chrysoula Doxani, Athina Tatsioni
Summary: This study suggests that exercise intervention during pregnancy can reduce the risk of gestational diabetes mellitus (GDM) in high-risk women. The protective effect is further supported in women with low education level, intervention duration longer than 20 weeks, and a motivation component in the intervention. Large-scale, high-quality randomized controlled trials are needed to confirm these findings.
Review
Biochemistry & Molecular Biology
Katarzyna Piotrowska, Katarzyna Zgutka, Marta Tkacz, Maciej Tarnowski
Summary: Diabetes is a major healthcare problem, especially for pregnant women, and requires an appropriate approach. Gestational diabetes mellitus and type 2 diabetes mellitus share many similarities and induce oxidative stress and cellular stress signaling. The risk of diabetes during pregnancy can lead to complications for both the mother and fetus. Physical activity is not only important for treating the negative effects of diabetes, but also for preventing its progression and reversing changes. Regular training sessions have a positive effect on the immune status of diabetic patients, mothers, and fetuses, causing changes in immune cell levels, cytokine activation, production and secretion, as well as microRNA, which improve overall well-being.
Article
Multidisciplinary Sciences
Elena Duschek, Lukas Forer, Sebastian Schoenherr, Christian Gieger, Annette Peters, Florian Kronenberg, Harald Grallert, Claudia Lamina
Summary: The availability of polygenic scores for type 2 diabetes (T2D) raises the question of whether family history assessment might become redundant. This study aimed to assess the independent and combined effects of family risk score (FamRS) and polygenic score (PGS) on T2D risk. The results showed that both genetic information and family history are relevant for predicting T2D risk and could be used for identifying high-risk groups for personalized prevention measures.
SCIENTIFIC REPORTS
(2023)
Article
Nutrition & Dietetics
Chunmei Mi, Hong Liu, Hongying Peng, Chunxia Cheng, Meng Wang, Hua Liu, Guo Feng, Jinru Wu, Hao Nie, Min Liu
Summary: The study revealed a correlation between maternal body mass index and oral glucose tolerance test results, indicating that women who were overweight before pregnancy were more likely to develop hyperglycemia. Additionally, abnormal 2-hour postprandial glucose levels during gestational oral glucose tolerance test may influence postpartum oral glucose tolerance test outcomes.
FRONTIERS IN NUTRITION
(2021)
