4.6 Article

INFORMING THE SYMPTOM PROFILE OF COMPLICATED GRIEF

Journal

DEPRESSION AND ANXIETY
Volume 28, Issue 2, Pages 118-126

Publisher

WILEY
DOI: 10.1002/da.20775

Keywords

complicated grief; symptoms; grief; loss; DSM; diagnostic criteria; factor analyses; IRT

Funding

  1. Massachusetts General Hospital
  2. National Institute of Mental Health [1R01MH077700, MH60783, MH70741]
  3. Highland Street Foundation
  4. American Foundation for Suicide Prevention
  5. Astra Zeneca
  6. Cephalon
  7. Forest Laboratories
  8. NARSAD
  9. NIMH
  10. Glaxo SmithKline
  11. Janssen
  12. Lilly
  13. Pfizer
  14. Sepracor
  15. UCB-Pharma
  16. NIH
  17. ADEC webinar
  18. University of Manitoba
  19. Winnipeg
  20. University of Memphis

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Background: Complicated Grief (CG) is under consideration as a new diagnosis in DSM5. We sought to add empirical support to the current dialogue by examining the commonly used Inventory of Complicated Grief (ICG) scale completed by 782 bereaved individuals. Methods: We employed IRT analyses, factor analyses, and sensitivity and specificity analyses utilizing our full sample (n = 782), and also compared confirmed CG cases (n = 288) to noncases (n = 377). Confirmed CG cases were defined as individuals bereaved at least 6 months who were seeking care for CG, had an ICG >= 30, and received a structured clinical interview for CG by a certified clinician confirming CG as their primary illness. Noncases were bereaved individuals who did not present with CG as a primary complaint (including those with depression, bipolar disorder, anxiety disorders, and controls) and had an ICG<25. Results: IRT analyses provided guidance about the most informative individual items and their association with CG severity. Factor analyses demonstrated a single factor solution when the full sample was considered, but within CG cases, six symptom clusters emerged: (1) yearning and preoccupation with the deceased, (2) anger and bitterness, (3) shock and disbelief (4) estrangement from others, (5) hallucinations of the deceased, and (6) behavior change, including avoidance and proximity seeking. The presence of at least one symptom from three different symptom clusters optimized sensitivity (94.8%) and specificity (98.1%). Conclusions: These data, derived from a diverse and predominantly clinical help seeking population, add an important perspective to existing suggestions for DSM5 criteria for CG. Depression and Anxiety 28:118-126, 2011. (C) 2010 Wiley-Liss, Inc.

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