Article
Polymer Science
Mohd Yazid Bajuri, Jeehee Kim, Yeongseo Yu, Muhammad Shazwan Shahul Hameed
Summary: This pilot study shows that 3D-bioprinted autologous adipose tissue grafts, with the addition of fibrin gel, can effectively treat diabetic foot ulcers. Seven out of ten patients achieved complete healing within 12 weeks, with no adverse events observed.
Article
Orthopedics
Baris Gorgun, Alper Gamli, Mehmet Emin Duran, Berhan Bayram, Tekin Kerem Ulku, Baris Kocaoglu
Summary: This study compared the efficacy of single-step all-arthroscopic treatment of osteochondral lesions of the talus (OLT) with and without the use of a collagen scaffold. The results showed no significant difference between the two groups in terms of clinical and radiological outcomes.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Luis Fernandez-Vega-Cueto, Mairobi Persinal-Medina, Natalia Vazquez, Manuel Chacon, Belen Alfonso-Bartolozzi, Sergio Alonso-Alonso, Teresa Sanchez, Silvia Berisa-Prado, Laura Maria Martinez-Lopez, Jesus Merayo-Lloves, Alvaro Meana
Summary: The study proposes a method to prepare autologous bio-based fibrin glue for ophthalmic surgery. The adhesive strength of FG increased with fibrinogen concentration, and FG2 and FG3 showed successful results in conjunctival autografts with equivalent properties compared to commercial FG and reduced inflammation.
Article
Ophthalmology
Christine Cioba, Samara Barbara Marafon, Barbara Gastal Borges Fortes, Mariana Thome Cavalheiro, Marcelo Fabris, Gustavo Michel, Gabriela Maria Zambon, Alexandre Marcon, Diane Ruschel Marinho
Summary: The purpose of this study was to compare the effectiveness of autologous fibrin glue and traditional sutures for conjunctival graft attachment in patients undergoing pterygium excision surgery. The results showed that autologous fibrin glue had a higher graft loss rate compared to sutures, however, it had a shorter surgical time and lower pain scores. Therefore, autologous fibrin glue can be a cost-effective alternative to sutures in certain situations.
INTERNATIONAL OPHTHALMOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Chengwei Tu, Aisha Bajwa, Andi Shi, Gang Wu, Jingxiao Wang
Summary: The results of this study showed that the combination of deproteinized bovine bone and autologous bone grafts stimulated calvarial bone defect regeneration, while the addition of fibrin glue did not accelerate new bone formation.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Materials Science, Multidisciplinary
Wentao Shi, Yunduan Que, Xuan Zhang, Lu Bian, Xuejian Yu, Xue Tang, Guofeng Yang, Yao Dai, Shiqi Bi, Demin Lv, Yuyan Weng, Weijiang Wu, Zhijian Zhang, Xiaojie Lu, Naiyan Lu
Summary: The study developed a novel biofunctional live tissue-engineered bone-like graft, demonstrating that overexpression of TG2 by stem cells promoted osteogenic differentiation and improved bone regeneration for bone defect repair.
NPG ASIA MATERIALS
(2021)
Article
Cell & Tissue Engineering
Yongfeng Li, Huawei Liu, Chao Wang, Rongzeng Yan, Lei Xiang, Xiaodan Mu, Lingling Zheng, Changkui Liu, Min Hu
Summary: This study aimed to fabricate 3D-printing titanium grid scaffolds to achieve bone fusion in mandibular segmental defects. The results showed that the scaffolds with sufficient pores and basic biomechanical strength could facilitate bone regeneration and integration of bone broken ends. Clinical observations on both animal models and patients confirmed the successful bone regeneration in mandibular defects using the titanium grid scaffolds.
NPJ REGENERATIVE MEDICINE
(2023)
Review
Dermatology
Sara Sadeghi, Yekta Ghane, Nima Hajizadeh, Azadeh Goodarzi
Summary: Autologous fat tissue injection has shown promising effects in treating alopecia, particularly in scarring alopecia. It induces angiogenesis and supports hair regrowth. It also holds promise for non-scarring alopecia. The adipose-derived regenerative cells (ADRCs) in adipose tissue secrete growth factors and have anti-inflammatory and anti-oxidative properties.
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Article
Chemistry, Physical
Giulia Mazzucchi, Marco Lollobrigida, Luca Lamazza, Giorgio Serafini, Dario Di Nardo, Luca Testarelli, Alberto De Biase
Summary: This preliminary study suggests that autologous dentin grafts can be effective in preventing periodontal defects after surgical extraction of impacted or semi-impacted lower third molars. The results show a reduction in probing pocket depth and an increase in bone gain with the use of autologous dentin grafts.
Article
Cell & Tissue Engineering
Yu Yang, Xin Wang, Kangkang Zha, Zhuang Tian, Shuyun Liu, Xiang Sui, Zhigang Wang, Jilian Zheng, Jun Wang, Xiaobin Tian, Quanyi Guo, Jinmin Zhao
Summary: Xenogeneic porcine fibrin sealant is used as a scaffold for cartilage tissue engineering, showing promising results in promoting cartilage defect repair when combined with autologous chondrocytes in rabbits, indicating broad prospects for clinical applications.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
(2021)
Article
Veterinary Sciences
Anamika Changrani-Rastogi, Krutika Swadi, Mitali Barve, Niyati Bajekal
Summary: This study evaluated the effect of autologous platelet-rich fibrin (PRF) in the management of feline cutaneous wounds. The results showed that PRF could serve as a low-risk and convenient adjunctive therapy to promote wound healing in cats.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Clinical Neurology
Katsumi Takizawa, Daiki Okazaki, Yoshitaka Takegawa, Yuki Koga, Masataka Sagata, Kenichi Michishita, Noriko Shinya
Summary: The study found that combining gelatin sponge with fibrin glue in neurosurgery can achieve a stronger and faster hemostatic effect compared to other methods. This combination is useful for various venous hemorrhages and shows a very good compatibility between the two substances.
Article
Health Care Sciences & Services
Ralf Rothoerl, Junee Tomelden, Eckhard Udo Alt
Summary: In this study, long-term results of 37 patients with facet joint syndrome treated with autologous unmodified adipose tissue-derived regenerative cells were observed. The patients reported improved quality of life after the treatment.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Orthopedics
Thomas Richard Niethammer, Felix Uhlemann, Anja Zhang, Martin Holzgruber, Ferdinand Wagner, Peter Ernst Mueller
Summary: This study compares the outcomes of hydrogel-based autologous chondrocyte implantation and scaffold-based autologous chondrocyte implantation for the treatment of cartilage defects in the knee joint. The results show that both methods show significant improvements in subjective well-being of patients after a 2-year follow-up, with hydrogel-based autologous chondrocyte implantation group showing more significant improvements after 6 months.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2022)
Article
Materials Science, Multidisciplinary
Jiangqi Cheng, Kai Shen, Qiang Zuo, Kai Yan, Xiao Zhang, Wenwei Liang, Weimin Fan
Summary: This study developed a bioactive multiphase scaffold for osteochondral repair by decellularizing an intact osteochondral graft. The porosity and mechanical properties of the scaffold were optimized using laser drilling and collagen digestion, promoting the recellularization of cartilage layer. The experimental results showed that the multiphasic scaffold had excellent mechanical properties and structural stability similar to normal rabbit osteochondral tissue, and significantly facilitated the concurrent regeneration of cartilage and subchondral bone in a rabbit model.
MATERIALS & DESIGN
(2023)
Article
Food Science & Technology
Seyed Jalil Masoumi, Davood Mehrabani, Mehdi Saberifiroozi, Mohammad Reza Fattahi, Fariba Moradi, Masoud Najafi
Summary: The study demonstrates that probiotic yogurt fortified with L. acidophilus and Bifidobacterium sp. can effectively reduce lactose intolerance symptoms, safely lower hydrogen levels in breath tests, and is recommended as a treatment option for lactose intolerance patients.
FOOD SCIENCE & NUTRITION
(2021)
Review
Medicine, General & Internal
Reza Kaboodkhani, Davood Mehrabani, Feridoun Karimi-Busheri
Summary: Otorhinolaryngology involves surgeries on various tissues of the head and neck that control functions like hearing, breathing, and balance. Regenerative medicine offers a new approach by using cell transplantation to promote healing and replacement of damaged tissues. Mesenchymal stem cells have great potential in treating craniofacial defects and diseases in otorhinolaryngology, with their wide range of healing functions and low risk of rejection.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Polymer Science
Mohadeseh Rezaei, Nahid Hassanzadeh Nemati, Davood Mehrabani, Ali Komeili
Summary: "The incorporation of CUC in the scaffold enhanced elasticity and antibacterial properties, while also improving cell viability and attachment to the scaffold in skin tissue engineering."
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Materials Science, Textiles
Mohadeseh Rezaie, Nahid Hassanzadeh Nemati, Davood Mehrabani, Ali Komeili
Summary: This study investigated the elasticity, degradation, and mechanical strength of SCMC and CA-based scaffolds, as well as their effects on fibroblasts. The results showed that the SCMC/CA nanofiber scaffolds had favorable properties for skin tissue engineering applications, with high porosity, elasticity, and biological compatibility.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Public, Environmental & Occupational Health
Parisa Soltan-Alinejad, Hamzeh Alipour, Aboozar Soltani, Qasem Asgari, Amin Ramezani, Davood Mehrabani, Kourosh Azizi
Summary: This study characterized and cloned the PLA(2) enzyme called Maurolipin from Iranian Scorpio maurus venom. In silico analyses revealed the difference in genetic and protein structures of PLA(2) based on scorpion species and geographical conditions.
JOURNAL OF TROPICAL MEDICINE
(2022)
Article
Respiratory System
Shahin Kavousi, Hossein Akbarialiabad, Davood Mehrabani, Alireza Mohamadian, Aria Ghahramani, Ali Shirkhoda, Reza Jalli
Summary: In survivors exposed to Sulfur Mustard, patients with bronchiectasis and lung fibrosis have a significantly higher risk of developing lung cancers, necessitating close follow-up of these victims.
BMC PULMONARY MEDICINE
(2022)
Article
Medicine, General & Internal
Reza Jalli, Davood Mehrabani, Shahrokh Zare, Mahdi Saeedi Moghadam, Iman Jamhiri, Navid Manafi, Golshid Mehrabani, Janan Ghabanchi, Iman Razeghian Jahromi, Aghdass Rasouli-Nia, Feridoun Karimi-Busheri
Summary: This study assessed the tracking of iron oxide-labeled stem cells transfected by lipofectamine using magnetic resonance imaging (MRI) in vitro and in vivo. Rat dental pulp stem cells (DPSCs) were characterized, labeled with iron oxide nanoparticles, and then transfected with lipofectamine. The internalization of the nanoparticles was confirmed by Prussian blue staining and MRI tracking.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Emergency Medicine
Davood Mehrabani, Mehra Nazempour, Rouhollah Mehdinavaz-Aghdam, Seyedeh-Sara Hashemi, Reza Jalli, Mahdi Saeedi Moghadam, Shahrokh Zare, Iman Jamhiri, Javad Moayedi, Feridoun Karimi-Busheri
Summary: This study demonstrates that SPION labeling coupled with MRI can be used to track the fate of stem cells after transplantation in a burn model.
Review
Parasitology
Zahra Nasiri, Mohsen Kalantari, Jalal Mohammadi, Salman Daliri, Davood Mehrabani, Kourosh Azizi
Summary: This study reviewed the epidemiology, reservoirs, vectors, and climatic factors of cutaneous leishmaniasis (CL) in Iran. The prevalence of CL was found to be high in western Iran and has spread to the central and southern regions in recent years. Certain regions in southern Iran are notable hotspots for CL due to the presence of potential rodent hosts. Molecular identification using genomic diagnosis revealed heterogeneity in leishmaniasis across different parts of the country.
Article
Medicine, Research & Experimental
Kamyar Iravani, Davood Mehrabani, Aida Doostkam, Negar Azarpira, Pooya Iranpour, Mohsen Bahador, Soheila Mehravar
Summary: The study evaluated the efficacy of adipose tissue-derived mesenchymal stem cells (ASCs) on cartilaginous regeneration in an experimental rabbit model. The results showed that ASCs significantly increased cartilage regeneration, reduced inflammation, and fibrosis. Magnetic resonance imaging was proven to be a useful, noninvasive method for tracking correct ASCs placement and viability in cartilage regeneration.
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
(2022)
Article
Pharmacology & Pharmacy
Leyla Anari, Davood Mehrabani, Mahboobeh Nasiri, Shahrokh Zare, Iman Jamhiri, Jason P. Acker
Summary: This study investigated the effect of methamphetamine on proliferation, differentiation, and apoptosis of human adipose tissue stem cells. The findings showed that methamphetamine decreased the proliferation and differentiation properties of the stem cells, while increasing apoptosis.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
(2022)
Article
Surgery
Fariba Jaafari-Sheybani, Seyed-Ebrahim Hosseini, Davood Mehrabani, Amin Derakhshanfar, Feridoun Karimi-Busheri
Summary: This study demonstrated that METH use in experimental rats led to increased anxiety levels and histological inflammation, degeneration, and necrosis in adipose tissue, highlighting the dangers of recreational METH use for weight loss purposes.
WORLD JOURNAL OF PLASTIC SURGERY
(2021)
Article
Surgery
Seyedeh-Sara Hashemi, Mahdukht Mahmoodi, Hamid Reza Tohidinik, Ali Akbar Mohammadi, Davood Mehrabani
Summary: This study evaluated the epidemiology of burn and LA50 in children in Shiraz, Southern Iran from 2012 to 2016. The findings showed that male patients were more than females, but the mortality rate was higher in females. Additionally, scald and flame were the most common causes of burn.
WORLD JOURNAL OF PLASTIC SURGERY
(2021)
Article
Parasitology
Qasem Asgari, Mohammad Hossein Motazedian, Amir Khazanchin, Davood Mehrabani, Shahrbanou Naderi Shahabadi
Summary: This study investigated the potential association between Toxoplasma gondii infection and Type I diabetes, revealing a higher prevalence of Toxoplasma infection in Type I diabetes patients. Interestingly, there was a higher rate of IgG positivity in patients with a positive family history of Type I diabetes.
JOURNAL OF PARASITOLOGY RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Zahra Khodabandeh, Parisa Dolati, Mohammad Javad Zamiri, Davood Mehrabani, Hossein Bordbar, Sanaz Alaee, Iman Jamhiri, Negar Azarpira
Summary: Exposure to lead acetate had toxic effects on testicular structure and activation of the apoptotic pathways, while co-administration of quercetin partially alleviated these adverse effects.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
