Phase II Crossover Trial of Varenicline in Mild-to-Moderate Alzheimer's Disease

2011 Alzheimer’s disease facts and figures

(2011)   Alzheimers & Dementia

Targeting the nicotinic alpha7 acetylcholine receptor to enhance cognition in disease

(2011) Tanya L. Wallace et al.   BIOCHEMICAL PHARMACOLOGY

Varenicline prevents affective and cognitive exacerbation during smoking abstinence in male patients with schizophrenia

(2011) Mu-En Liu et al.   PSYCHIATRY RESEARCH

Pre-clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

(2010) H Rollema et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Varenicline for Smoking Cessation

(2010) Hélène M. Faessel et al.   CLINICAL PHARMACOKINETICS

Quantitative Assessment of Exposure–Response Relationships for the Efficacy and Tolerability of Varenicline for Smoking Cessation

(2010) P Ravva et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Double-Blind, Controlled Phase II Study of a 5-HT6 Receptor Antagonist, SB-742457, in Alzheimers Disease

(2010) G. Maher-Edwards et al.   Current Alzheimer Research

Decreased cerebral α4β2* nicotinic acetylcholine receptor availability in patients with mild cognitive impairment and Alzheimer’s disease assessed with positron emission tomography

(2010) Kai Kendziorra et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Pharmacokinetics, Safety, and Tolerability Following Multiple Oral Doses of Varenicline Under Various Titration Schedules in Elderly Nonsmokers

(2010) Qinying Zhao et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A randomized double-blind study comparing 25 and 50 mg TC-1734 (AZD3480) with placebo, in older subjects with age-associated memory impairment

(2010) Geoffrey C Dunbar et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Preclinical pharmacology of the α4β2 nAChR partial agonist varenicline related to effects on reward, mood and cognition

(2009) Hans Rollema et al.   BIOCHEMICAL PHARMACOLOGY

Population pharmacokinetic analysis of varenicline in adult smokers

(2009) Patanjali Ravva et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Association between a Genetic Variant of the Alpha-7 Nicotinic Acetylcholine Receptor Subunit and Four Types of Dementia

(2009) Ágnes Fehér et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder

(2009) Robert C. Smith et al.   SCHIZOPHRENIA RESEARCH

Behavioral effects of current Alzheimer’s disease treatments: A descriptive review

(2008) Jeffrey L. Cummings et al.   Alzheimers & Dementia

Varenicline Improves Mood and Cognition During Smoking Abstinence

(2008) Freda Patterson et al.   BIOLOGICAL PSYCHIATRY