Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells

Overlapping DNA Methylation Dynamics in Mouse Intestinal Cell Differentiation and Early Stages of Malignant Progression

(2015) Marta Forn et al.   PLoS One

FXR silencing in human colon cancer by DNA methylation and KRAS signaling

(2013) Ann M. Bailey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Linking inflammation to tumorigenesis in a mouse model of high-fat-diet-enhanced colon cancer

(2013) Stani D. Day et al.   CYTOKINE

Gestational exposure to the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin induces BRCA-1 promoter hypermethylation and reduces BRCA-1 expression in mammary tissue of rat offspring: Preventive effects of resveratrol

(2013) Andreas J. Papoutsis et al.   MOLECULAR CARCINOGENESIS

DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer

(2013) Christina Grimm et al.   PLoS Genetics

Epigenetic Differences in Normal Colon Mucosa of Cancer Patients Suggest Altered Dietary Metabolic Pathways

(2012) M. L. Silviera et al.   Cancer Prevention Research

Consumption of high-fat diet induces tumor progression and epithelial–mesenchymal transition of colorectal cancer in a mouse xenograft model

(2012) Feng-Yao Tang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

High-fat-induced intestinal permeability dysfunction associated with altered fecal bile acids

(2012) Lotta K Stenman   WORLD JOURNAL OF GASTROENTEROLOGY

Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice

(2011) Richard Kellermayer et al.   FASEB JOURNAL

Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis

(2011) Salvatore Modica et al.   GASTROENTEROLOGY

Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis

(2011) Sigurd Lax et al.   INTERNATIONAL JOURNAL OF CANCER

Bile acids and colon cancer: Solving the puzzle with nuclear receptors

(2011) Chiara Degirolamo et al.   TRENDS IN MOLECULAR MEDICINE

Sodium taurocholate inhibits intestinal adenoma formation in APCMin/+ mice, potentially through activation of the farnesoid X receptor

(2010) D. L. H. Smith et al.   CARCINOGENESIS

Resveratrol Prevents Epigenetic Silencing of BRCA-1 by the Aromatic Hydrocarbon Receptor in Human Breast Cancer Cells

(2010) Andreas J. Papoutsis et al.   JOURNAL OF NUTRITION

Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study

(2009)   GUT

Nuclear Bile Acid Receptor FXR Protects against Intestinal Tumorigenesis

(2008) S. Modica et al.   CANCER RESEARCH

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

Farnesoid X Receptor Deficiency in Mice Leads to Increased Intestinal Epithelial Cell Proliferation and Tumor Development

(2008) R. R.M. Maran et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Apc mice: Models, modifiers and mutants

(2008) Amy E. McCart et al.   PATHOLOGY RESEARCH AND PRACTICE