Journal
DALTON TRANSACTIONS
Volume 42, Issue 4, Pages 1267-1277Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2dt31337e
Keywords
-
Categories
Funding
- University of Cape Town
- National Research Foundation (NRF) of South Africa
- South African Medical Research Council (MRC)
- Deutscher Akademischer Austausch Dienst (DAAD)
- Swiss National Science Foundation
- MRC
Ask authors/readers for more resources
Cationic N,O-chelating dendrimers functionalised on the periphery with RAPTA-like (ruthenium(II)-arene-1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane) moieties have been synthesised and characterised using NMR and IR spectroscopy, elemental analysis and MALDI-TOF/HR-ESI mass spectrometry. Metallodendrimers from the first to the fourth-generation containing up to 32 peripheral ruthenium-arene-PTA moieties were obtained. Model mononuclear analogues, [{Ru(eta(6)-p-cymene)((C7H5NO)-kappa(2)-N,O)(PTA)}((CH2)(3))][PF6] and [{Ru(eta(6)hexamethylbenzene)((C7H5NO)-kappa(2)-N,O)(PTA)}((CH2)(3))][PF6], have been prepared and their structures were determined by single crystal X-ray diffraction analysis. The cytotoxicities of the metallodendrimers and their mononuclear analogues were established on A2780 and A2780cisR human ovarian carcinoma cancer cells and model human embryonic kidney (HEK) cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available