The therapeutic potential of metal-based antimalarial agents: Implications for the mechanism of action

The antimalarial ferroquine: from bench to clinic

(2013) C. Biot et al.   Parasite

4-aminoquinoline analogues and its platinum (II) complexes as antimalarial agents

(2011) Nicolli Bellotti de Souza et al.   BIOMEDICINE & PHARMACOTHERAPY

Malaria and other vector-borne infection surveillance in the U.S. Department of Defense Armed Forces Health Surveillance Center-Global Emerging Infections Surveillance program: review of 2009 accomplishments

(2011) Mark M Fukuda et al.   BMC PUBLIC HEALTH

In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes

(2011) Faustine Dubar et al.   CHEMICAL COMMUNICATIONS

Synthesis, characterization and antimalarial activity of new chromium arene–quinoline half sandwich complexes

(2011) Lotta Glans et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, characterization and biological activity of trans-platinum(II) complexes with chloroquine

(2011) Maribel Navarro et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study

(2011) Jean-François Trape et al.   LANCET INFECTIOUS DISEASES

Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa

(2011) Amanda Leach et al.   MALARIA JOURNAL

Protection against Malaria by MSP3 Candidate Vaccine

(2011) Sodiomon B. Sirima et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ester prodrugs of ciprofloxacin as DNA-gyrase inhibitors: synthesis, antiparasitic evaluation and docking studies

(2011) Faustine Dubar et al.   MedChemComm

Heme as Trigger and Target for Trioxane-Containing Antimalarial Drugs†

(2010) Bernard Meunier et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Antimalarial Ferroquine: Role of the Metal and Intramolecular Hydrogen Bond in Activity and Resistance

(2010) Faustine Dubar et al.   ACS Chemical Biology

The Neutral Lipid Composition Present in the Digestive Vacuole ofPlasmodium falciparumConcentrates Heme and Mediates β-Hematin Formation with an Unusually Low Activation Energy

(2010) Anh N. Hoang et al.   BIOCHEMISTRY

Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure

(2010) Rodrigo Arancibia et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, Structure and in Vitro Biological Screening of Palladium(II) Complexes of Functionalised Salicylaldimine Thiosemicarbazones as Antimalarial and Anticancer Agents

(2010) Prinessa Chellan et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

The Selenium-independent Inherent Pro-oxidant NADPH Oxidase Activity of Mammalian Thioredoxin Reductase and Its Selenium-dependent Direct Peroxidase Activities

(2010) Qing Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mechanism of antimalarial action of [Au(CQ)(PPh3)]PF6: Structural effects and increased drug lipophilicity enhance heme aggregation inhibition at lipid/water interfaces

(2010) Maribel Navarro et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Trioxaferroquines as New Hybrid Antimalarial Drugs

(2010) François Bellot et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ferrocene–indole hybrids for cancer and malaria therapy

(2010) Josefina Quirante et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Shrinking the malaria map: progress and prospects

(2010) Richard GA Feachem et al.   LANCET

Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker

(2009) Natascha Chavain et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Crystallization of synthetic haemozoin (β-haematin) nucleated at the surface of lipid particles

(2009) Anh N. Hoang et al.   DALTON TRANSACTIONS

Synthesis, Characterization, and in vitro Antimalarial and Antitumor Activity of New Ruthenium(II) Complexes of Chloroquine

(2009) Chandima S. K. Rajapakse et al.   INORGANIC CHEMISTRY

The antimalarial activity of Ru–chloroquine complexes against resistant Plasmodium falciparum is related to lipophilicity, basicity, and heme aggregation inhibition ability near water/n-octanol interfaces

(2009) Alberto Martínez et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extended-Release Niacin or Ezetimibe and Carotid Intima–Media Thickness

(2009) Allen J. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

In Vitro Activity of Ferroquine Is Independent of Polymorphisms in Transport Protein Genes Implicated in Quinoline Resistance in Plasmodium falciparum

(2008) M. Henry et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: Synthesis, and in vitro antimalarial activity

(2008) Jean Guillon et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes

(2008) Alexander G. Maier et al.   CELL

The Fight Against Drug-Resistant Malaria: Novel Plasmodial Targets and Antimalarial Drugs

(2008) Mitchell Avery et al.   CURRENT MEDICINAL CHEMISTRY

New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro : Mechanistic and pharmacological implications

(2008) Anna Rosa Sannella et al.   FEBS LETTERS

The skin stage of malaria infection: biology and relevance to the malaria vaccine effort

(2008) Photini Sinnis et al.   Future Microbiology

The mechanism of antimalarial action of the ruthenium(II)–chloroquine complex [RuCl2(CQ)]2

(2008) Alberto Martínez et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials

(2008) Chiara Gabbiani et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Structure–activity relationships of 4-N-substituted ferroquine analogues: Time to re-evaluate the mechanism of action of ferroquine

(2008) Christophe Biot et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Investigation of the Redox Behavior of Ferroquine, a New Antimalarial

(2008) Natascha Chavain et al.   MOLECULAR PHARMACEUTICS

Ferroquine, an Ingenious Antimalarial Drug –Thoughts on the Mechanism of Action

(2008) Faustine Dubar et al.   MOLECULES

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

(2008) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selection of a trioxaquine as an antimalarial drug candidate

(2008) F. Cosledan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis, characterization and antiprotozoal studies of some metal complexes of antimalarial drugs

(2008) Peter A. Ajibade et al.   TRANSITION METAL CHEMISTRY

Antimalarial quinolones: Synthesis, potency, and mechanistic studies

(2007) Rolf W. Winter et al.   EXPERIMENTAL PARASITOLOGY

Recent advances in understanding the mechanism of hemozoin (malaria pigment) formation

(2007) Timothy J. Egan   JOURNAL OF INORGANIC BIOCHEMISTRY

Hemozoin: Oil versus water

(2007) John M. Pisciotta et al.   PARASITOLOGY INTERNATIONAL