Emerging trends in metalloprotein inhibition

Hydrogen Peroxide Activated Matrix Metalloproteinase Inhibitors: A Prodrug Approach

(2010) Jody L. Major Jourden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical and Pharmacological Analyses of HIV-1 Integrase Flexible Loop Mutants Resistant to Raltegravir

(2010) Mathieu Métifiot et al.   BIOCHEMISTRY

Enzymatic activation of a matrix metalloproteinase inhibitor

(2010) Jody L. Major Jourden et al.   CHEMICAL COMMUNICATIONS

Chelator Fragment Libraries for Targeting Metalloproteinases

(2010) Arpita Agrawal et al.   ChemMedChem

Identifying Chelators for Metalloprotein Inhibitors Using a Fragment-Based Approach

(2010) Jennifer A. Jacobsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

From Sensors to Silencers: Quinoline- and Benzimidazole-Sulfonamides as Inhibitors for Zinc Proteases

(2010) Matthieu Rouffet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Retroviral intasome assembly and inhibition of DNA strand transfer

(2010) Stephen Hare et al.   NATURE

To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition

(2009) Jennifer A. Jacobsen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Prochelator Activated by Hydrogen Peroxide Prevents Metal-Induced Amyloid β Aggregation

(2009) Marina G. Dickens et al.   CHEMBIOCHEM

Coordination Chemistry Based Approach to Lipophilic Inhibitors of 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase

(2009) Lisheng Deng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalysis and Inhibition ofMycobacterium tuberculosisMethionine Aminopeptidase

(2009) Jing-Ping Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

(2009) Erik Serrao et al.   Retrovirology

Comparison of Raltegravir and Elvitegravir on HIV-1 Integrase Catalytic Reactions and on a Series of Drug-Resistant Integrase Mutants†

(2008) Jessica Marinello et al.   BIOCHEMISTRY

Self-immolative dendritic probe for direct detection of triacetone triperoxide

(2008) Eran Sella et al.   CHEMICAL COMMUNICATIONS

Zinc-Binding Groups Modulate Selective Inhibition of MMPs

(2008) Arpita Agrawal et al.   ChemMedChem

Altering pyridinone N-substituents to optimise activity as potential prodrugs for Alzheimer's disease

(2008) Lauren E. Scott et al.   DALTON TRANSACTIONS

Recent Developments in Fragment-Based Drug Discovery

(2008) Miles Congreve et al.   JOURNAL OF MEDICINAL CHEMISTRY

Histone Deacetylase Inhibitors: From Bench to Clinic

(2008) Marielle Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Inhibitors ofEscherichia coliMethionine Aminopeptidase with the Fe(II)-Form Selectivity and Antibacterial Activity†

(2008) Wen-Long Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

(2008) Vincenzo Summa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY

Prodrug Strategies in Anticancer Chemotherapy

(2007) Felix Kratz et al.   ChemMedChem