Ndel1, Nudel ( Noodle): Flexible in the cell?

The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein

(2011) Eliza Żyłkiewicz et al.   JOURNAL OF CELL BIOLOGY

PKA Phosphorylation of NDE1 Is DISC1/PDE4 Dependent and Modulates Its Interaction with LIS1 and NDEL1

(2011) N. J. Bradshaw et al.   JOURNAL OF NEUROSCIENCE

The phospholipase A2 enzyme complex PAFAH Ib mediates endosomal membrane tubule formation and trafficking

(2011) Marie E. Bechler et al.   MOLECULAR BIOLOGY OF THE CELL

The Cytoskeletal Protein Ndel1 Regulates Dynamin 2 GTPase Activity

(2011) Mathieu Chansard et al.   PLoS One

Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective

(2010) Simone A Fietz et al.   CURRENT OPINION IN NEUROBIOLOGY

Functional Dissection of LIS1 and NDEL1 Towards Understanding the Molecular Mechanisms of Cytoplasmic Dynein Regulation

(2010) Takayuki Torisawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Dynein Binding Domain in Nudel Essential for Spindle Pole Organization inXenopusEgg Extract

(2010) Shusheng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The phospholipase complex PAFAH Ib regulates the functional organization of the Golgi complex

(2010) Marie E. Bechler et al.   JOURNAL OF CELL BIOLOGY

Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth

(2010) Mirian A.F. Hayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development

(2010) Karun K. Singh et al.   NEURON

Genetic Mosaic Dissection of Lis1 and Ndel1 in Neuronal Migration

(2010) Simon Hippenmeyer et al.   NEURON

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Lissencephaly: Mechanistic insights from animal models and potential therapeutic strategies

(2010) Anthony Wynshaw-Boris et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Animal models of gene–environment interactions in schizophrenia

(2009) Yavuz Ayhan et al.   BEHAVIOURAL BRAIN RESEARCH

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity

(2009) Anat Shmueli et al.   EMBO JOURNAL

Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

(2009) Hristelina Ilieva et al.   JOURNAL OF CELL BIOLOGY

Introducing intermediate filaments: from discovery to disease

(2009) John E. Eriksson et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Dose-Dependent Cortical Neuronal Migration and Neurite Extension Defects in Lis1 and Ndel1 Mutant Mice

(2009) Y. H. Youn et al.   JOURNAL OF NEUROSCIENCE

Rabex-5 Is a Rab22 Effector and Mediates a Rab22-Rab5 Signaling Cascade in Endocytosis

(2009) Huaiping Zhu et al.   MOLECULAR BIOLOGY OF THE CELL

Aurora A moonlights in neurite extension

(2009) Gloria Kuo Lefkowitz et al.   NATURE CELL BIOLOGY

An essential role of the aPKC–Aurora A–NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

(2009) Daisuke Mori et al.   NATURE CELL BIOLOGY

Requirement for Nudel and dynein for assembly of the lamin B spindle matrix

(2009) Li Ma et al.   NATURE CELL BIOLOGY

Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly

(2009) Masami Yamada et al.   NATURE MEDICINE

DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212

(2009) Ju Young Kim et al.   NEURON

Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport

(2009) Qiangge Zhang et al.   TRAFFIC

Emerging roles for myosin II and cytoplasmic dynein in migrating neurons and growth cones

(2009) Richard B. Vallee et al.   TRENDS IN CELL BIOLOGY

Nudel and FAK as Antagonizing Strength Modulators of Nascent Adhesions through Paxillin

(2009) Yongli Shan et al.   PLOS BIOLOGY

DISC1, PDE4B, and NDE1 at the centrosome and synapse

(2008) Nicholas J. Bradshaw et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Putting a Notch in Our Understanding of Nuclear Migration

(2008) Joshua J. Buchman et al.   CELL

Neuroepithelial Stem Cell Proliferation Requires LIS1 for Precise Spindle Orientation and Symmetric Division

(2008) Jessica Yingling et al.   CELL

Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA)

(2008) Daniel M. Collins et al.   CELLULAR SIGNALLING

Intermediate filaments: versatile building blocks of cell structure

(2008) Robert D Goldman et al.   CURRENT OPINION IN CELL BIOLOGY

Nudel Binds Cdc42GAP to Modulate Cdc42 Activity at the Leading Edge of Migrating Cells

(2008) Yidong Shen et al.   DEVELOPMENTAL CELL

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein

(2008) Masami Yamada et al.   EMBO JOURNAL

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: Evidence of epistasis and competitive binding

(2008) K. E. Burdick et al.   HUMAN MOLECULAR GENETICS

Ndel1 Controls the Dynein-mediated Transport of Vimentin during Neurite Outgrowth

(2008) Su Yeon Shim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells

(2008) Sachin Hebbar et al.   JOURNAL OF CELL BIOLOGY

Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation

(2008) Kazuhito Toyo-oka et al.   JOURNAL OF CELL BIOLOGY

Ndel1 Promotes Axon Regeneration via Intermediate Filaments

(2008) Cory Toth et al.   PLoS One

How has DISC1 enabled drug discovery?

(2007) Qi Wang et al.   MOLECULAR AND CELLULAR NEUROSCIENCE