Journal
CYTOSKELETON
Volume 67, Issue 10, Pages 609-629Publisher
WILEY
DOI: 10.1002/cm.20473
Keywords
protein structure; cytoskeleton; actin; actin-binding proteins; mutations; diseases
Categories
Funding
- Hungarian Science Foundation (OTKA) [K60968, K77840]
- Wellcome Trust
Ask authors/readers for more resources
Actin is a protein abundant in many cell types. Decades of investigations have provided evidence that it has many functions in living cells. The diverse morphology and dynamics of actin structures adapted to versatile cellular functions is established by a large repertoire of actin-binding proteins. The proper interactions with these proteins assume effective molecular adaptations from actin, in which its conformational transitions play essential role. This review attempts to summarise our current knowledge regarding the coupling between the conformational states of actin and its biological function. (C) 2010 Wiley-Liss, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available