Article
Rehabilitation
Sandra E. Rakers, Marieke E. Timmerman, Myrthe E. Scheenen, Myrthe E. de Koning, Harm J. van der Horn, Joukje van der Naalt, Jacoba M. Spikman
Summary: The study analyzed fatigue after mild traumatic brain injury (TBI) using latent class growth analysis (LCGA) to identify distinct recovery trajectories and investigate influencing factors. Results showed four patient clusters with different patterns of fatigue, emotional distress, and coping styles. Favorable recovery from posttraumatic fatigue was observed in 55% of mild TBI patients.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Psychology, Clinical
Karele Villeneuve, Simon Beaulieu-Bonneau, Carol Hudon, Guillaume Souesme, Marianne Levesque, David Predovan, Marie-Josee Sirois, Elaine de Guise, Marie-Eve Lamontagne, Valerie Poulin, Natalie Le Sage, Marcel Emond, Marie-Christine Ouellet
Summary: This study aimed to describe the subjective burden, objective burden, and psychological distress of care partners of older persons with traumatic brain injury (TBI) at 4 months postinjury, as well as explore the predictors of subjective burden and psychological distress. The study found that a majority of care partners reported objective burden, and a significant percentage experienced subjective burden and symptoms of anxiety or depression. Difficulties reported regarding the injured person and perceived social support were found to predict higher subjective burden and psychological distress. The study provides insights into the potential impacts of TBI on care partners of older adults and highlights the need for support in their psychological adaptation.
REHABILITATION PSYCHOLOGY
(2023)
Article
Psychology, Clinical
Namkee G. Choi, C. Nathan Marti, Diana M. DiNitto, Bryan Y. Choi
Summary: Based on the 2020 National Survey on Drug Use and Health data, this study found a high prevalence of psychological distress among cannabis users, especially among young adults. The study also revealed a positive correlation between the level of psychological distress and the risk of cannabis use disorder (CUD), with higher distress levels associated with greater CUD risk. Additionally, psychological distress was found to be associated with higher odds of having alcohol use disorder. These findings highlight the importance of providing behavioral health services to address the psychological distress and substance use issues, particularly among young adults.
JOURNAL OF PSYCHOACTIVE DRUGS
(2023)
Article
Clinical Neurology
Shun Tian, Tianyang Zhang, Xing Chen, Chen-Wei Pan
Summary: This study revealed a significant association between substance use and psychological distress among adolescents, especially with alcohol use linked to medium to high psychological distress. Region-wise analysis indicated that substance use was associated with psychological distress in the African, American, South-East, and Western Pacific regions.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Rehabilitation
Eric Xie, Michael Pellegrini, Zhibin Chen, Laura Jolliff, Maria Crotty, Julie Ratcliffe, Jacqui Morarty, Terence J. O'Brien, Natasha A. Lannin
Summary: This study aimed to determine the potential benefit of rehabilitation and the influence of substance use on outcomes in patients with traumatic brain injury (TBI). It found that a history of substance use was associated with lower reported quality of life at 12 months post-TBI.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Health Care Sciences & Services
Ayesha, Saboor Ahmad, Shazadi Saba, Muhammad Kashif, Danish Ali Khan, Absarul Haque, Muhammad Imran Naseer, Adel M. Abuzenadah, Anwar M. Hashem, Shafiq Ur Rehman
Summary: This study reveals a significant association between religious coping methods, religious practice, and psychological distress among caregivers of children with traumatic brain injury.
Article
Clinical Neurology
Markus Karlander, Johan Ljungqvist, Johan Zelano
Summary: The risk of post-traumatic epilepsy is considerable, with higher risks for focal cerebral injuries and diffuse cerebral injuries compared to mild TBI. The risk of epilepsy after any TBI was 4.0%, significantly higher than the control group's risk of 0.9%. Risk of epilepsy increased with severity of injury.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2021)
Article
Neurosciences
Arielle M. Levy, Michael M. Saling, Jacqueline F. I. Anderson
Summary: This study examined self-reported cognitive symptoms in individuals with mild traumatic brain injury (mTBI) and trauma controls (TCs), and found that subjective cognitive symptoms were significantly elevated after mTBI compared to TCs. Psychological distress and gender were identified as predictors of these symptoms, with females and those with higher distress reporting greater symptoms. These findings suggest the importance of considering interventions for females and individuals with high psychological distress following mTBI.
NEUROPSYCHOLOGICAL REHABILITATION
(2023)
Review
Behavioral Sciences
XiaoGuang Lin, XueLing Zhang, QinQin Liu, PanWen Zhao, Hui Zhang, HongSheng Wang, ZhongQuan Yi
Summary: The meta-analysis found that adult patients with TBI performed significantly worse in ToM tasks compared to healthy controls. There were impairments in individual ToM tasks, as well as in different stimulus modes and contents. Additionally, there was a positive association between ToM performance and Glasgow Coma Scale score. These findings suggest that ToM performance may be a good predictor of functional outcomes in adults with TBI.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Public, Environmental & Occupational Health
Ayomide T. David, Vinita Sharma, Lorna Bittencourt, Kelly K. Gurka, Juan Guillermo Perez-Carreno, Catalina Lopez-Quintero
Summary: This study examines the relationship between Serious Psychological Distress (SPD) and the quantity or frequency of substance use among pregnant women in the United States (US). The results show that pregnant women experiencing SPD had higher rates of smoking, binge drinking, and cannabis use compared to those who did not report SPD.
PREVENTIVE MEDICINE
(2023)
Review
Critical Care Medicine
Kaitlin M. Best, Marissa M. Mojena, Gordon A. Barr, Heath D. Schmidt, Akiva S. Cohen
Summary: Traumatic brain injury (TBI) is associated with chronic pain and substance use disorder (SUD), but the mechanisms underlying these conditions are not well understood. Dynorphin and its receptor KOR play important roles in chronic pain and SUD. This review highlights the potential involvement of dynorphin in long-term sequelae after TBI and identifies similarities between the pathophysiology of chronic pain, SUD, and TBI.
JOURNAL OF NEUROTRAUMA
(2022)
Article
Neurosciences
Angelle M. Sandera, Allison N. Clark, David B. Arciniegas, Kim Tran, Luis Leon-Novelo, Esther Ngan, Jay Bogaards, Mark Sherer, Robyn Walser
Summary: Psychological distress is common in individuals with traumatic brain injury, but treatments are still inadequate. This randomized controlled trial found that Acceptance and Commitment Therapy (ACT) significantly reduced psychological distress and improved psychological flexibility and commitment to action in persons with TBI. Results suggest that core ACT processes explain the variance in treatment outcomes.
NEUROPSYCHOLOGICAL REHABILITATION
(2021)
Article
Neurosciences
Maria Mazaharally, Sonja Stojanovski, Rebecca Trossman, Kamila Szulc-Lerch, M. Mallar Chakravarty, Brenda Colella, Joanna Glazer, Robin E. Green, Anne L. Wheeler
Summary: Progressive cortical volumetric loss is observed following moderate-severe traumatic brain injury (TBI), with thinner cortices and no significant changes in cortical surface area. The changes in CT and CSA exhibit widespread regional reductions and increases in TBI participants, suggesting differential neurodegenerative mechanisms at play. Additionally, the relationships between CT and CSA changes indicate complex bi-directional effects and highlight the importance of dissecting morphometric contributions to cortical volume change.
HUMAN BRAIN MAPPING
(2022)
Article
Psychology, Clinical
Mohammad Darharaj, Issa Hekmati, Farahnaz Mohammad Ghezel Ayagh, Ali Ahmadi, Mehmet Eskin, Hamed Abdollahpour Ranjbar
Summary: Substance use disorders are chronic conditions influenced by societal, psychological, and physiological factors. This study examined the relationship between difficulties in emotion regulation and drug craving in patients with SUDs, and found that psychological distress mediated this relationship.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2023)
Article
Biochemistry & Molecular Biology
Rany Vorn, Maiko Suarez, Jacob C. White, Carina A. Martin, Hyung-Suk Kim, Chen Lai, Si-Jung Yun, Jessica M. Gill, Hyunhwa Lee
Summary: In chronic mild traumatic brain injury (mTBI), dysregulation of exosomal microRNAs in plasma may indicate long-lasting neuronal inflammation, resulting in persistent post-injury symptoms.
Article
Psychology, Clinical
Gabriela Ilie, Ross Mason, David Bell, Greg Bailly, Ricardo A. Rendon, Robert Mann, Joseph G. Lawen, David Bowes, Derek Wilke, Nikhilesh Patil, Robert D. H. Rutledge
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2020)
Article
Oncology
Gabriela Ilie, Robert Rutledge, Ellen Sweeney
Article
Multidisciplinary Sciences
Smriti Singh, James Ted McDonald, Gabriela Ilie, Anil Adisesh
Article
Clinical Neurology
Abdelsimar T. Omar, David G. Munoz, Jeannette Goguen, John M. Lee, Fabio Rotondo, Kalman Kovacs, Michael D. Cusimano
Summary: Resection of the medial wall of the cavernous sinus using BETS appears to be safe and technically feasible for treating patients with functioning pituitary adenomas. There were no significant differences observed in biochemical remission and tumor control rates during the follow-up period in the cohort.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Article
Oncology
Gabriela Ilie, Robert Rutledge, Ellen Sweeney
Summary: The study showed that male survivors of prostate cancer are more likely to experience depression compared to survivors of other forms of cancer, and the risk is further impacted by household income levels.
Article
Sport Sciences
Darek Sokol-Randell, Mario Pasquale Rotundo, Gregory Tierney, Conor Deasy, Michael D. Cusimano
Summary: The study evaluated Potential Concussive Events (PCEs) in Gaelic football matches to understand the characteristics of these events and their impact on Sport-Related Concussion (SRC). The findings suggest that PCEs, which may not always result in a clinical diagnosis of SRC, are high-risk events that can be used as indicators. The data provides initial guidance for the development of player protection strategies to reduce the incidence and severity of SRC in Gaelic football.
JOURNAL OF SPORTS SCIENCES
(2021)
Article
Psychiatry
Andre J. McDonald, Steven Cook, Nigel E. Turner, Anca R. Ialomiteanu, Robert E. Mann, Susan J. Bondy, Michael Roerecke, John McCready, Dov Millstone, Hayley A. Hamilton, Tara Elton-Marshall, Juergen Rehm, Paul Kurdyak, Gabriela Ilie, Evelyn R. Vingilis, Christine M. Wickens, Mark van Der Maas, Michael D. Cusimano
Summary: The study shows that adult ADHD symptoms are significantly associated with psychological distress, while the relationship with hazardous drinking and problem gambling is not as strong.
PSYCHIATRY RESEARCH
(2021)
Review
Urology & Nephrology
Morgan MacDonald, Gabriella Ilie, Liam Power, Stewart Whalen, Robin Parker, Thomas A. A. Skinner, Andrea G. Lantz Powers
Summary: The routine use of tranexamic acid (TXA) during percutaneous nephrolithotomy (PCNL) was found to significantly reduce blood transfusion rates, mean hemoglobin (Hgb) drop, and operative time according to this meta-analysis. With its low cost and strong safety profile, endoscopic surgeons should strongly consider the routine use of TXA during PCNL.
JOURNAL OF ENDOUROLOGY
(2022)
Article
Food Science & Technology
Gheorghe-Ionut Ilie, Stefania-Adelina Milea, Gabriela Rapeanu, Adrian Circiumaru, Nicoleta Stanciuc
Summary: This study developed food-grade ingredients containing probiotics from kiwifruit byproducts, which were obtained by freeze-drying. The addition of these ingredients improved the phytochemical and probiotic content of protein bars.
Article
Public, Environmental & Occupational Health
Erin Keltie, Kalli M. Hood, Yunsong Cui, Ellen Sweeney, Gabriela Ilie, Anil Adisesh, Trevor Dummer, Veni Bharti, Jong Sung Kim
Summary: Chronic exposure to inorganic arsenic and trace metals is associated with prostate cancer, and altered arsenic methylation capacity may play an important role in arsenic carcinogenesis. In this study, toenails were found to be a viable biomarker for altered arsenic speciation in prostate cancer cases, and may be more useful than urine in this context.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Vincy Chan, Lauren Marcus, Danielle Burlie, Robert E. Mann, Danielle Toccalino, Michael D. Cusimano, Gabriela Ilie, Angela Colantonio
Summary: This study identified the social determinants of health associated with psychological distress and highlighted opportunities for targeted interventions, especially in providing accessible and affordable mental health support for individuals with lower income.
Article
Oncology
Lia Massoeurs, Gabriela Ilie, Tarek Lawen, Cody MacDonald, Cassidy Bradley, Jasmine Dang Cam-Tu Vo, Robert David Harold Rutledge
Summary: Recent research has shown that prostate cancer survivors are experiencing a silent epidemic of mental disorders. The study found that emotional and spiritual well-being are protective factors against mental disorders, while men with moderate to severe urinary tract symptoms were more likely to screen positive for mental disorders.
Article
Oncology
Cassidy Bradley, Gabriela Ilie, Cody MacDonald, Lia Massoeurs, Jasmine Dang Cam-Tu Vo, Robert David Harold Rutledge
Summary: This study examined the well-being of 367 men with a history of prostate cancer, finding that a portion of them experienced poor social/family, emotional, functional, and spiritual well-being. Treatment regret, mental and physical health indicators had an impact on men's well-being, with treatment regret, low household income, and poor physical and sexual function leading to decreased well-being. Good mental health was found to be protective against poor social/family, emotional, functional, and spiritual well-being.
Article
Oncology
Charles Gillis, Gabriela Ilie, Ross Mason, Gregory Bailly, Joseph Lawen, David Bowes, Nikhilesh Patil, Derek Wilke, Robert David Harold Rutledge, David Bell, Ricardo Rendon
Summary: The study examined the relationship between personality and mental health distress in prostate cancer patients. It found that screening positive for mental illness was associated with personality traits of low emotional stability and moderate to severe urinary problems. However, no association was identified between treatment for prostate cancer and personality type. Screening for mental health illness in this population may help reduce morbidity associated with cancer treatment and identify patients who may benefit from individualized mental health support services.
Article
Oncology
Gabriela Ilie, Robert Rutledge, Ellen Sweeney
Summary: Recent large population-based studies have shown an association between prostate cancer survivorship and mental health, with prostate cancer survivors who underwent surgery having higher odds of screening positive for depression symptoms compared to those with other forms of cancer. This highlights the importance of multidisciplinary survivorship care plans and comprehensive mental health support for prostate cancer survivors.