Article
Agriculture, Dairy & Animal Science
Pooja Devi, Mahendra Singh, Yallappa M. Somagond, Anjali Aggarwal
Summary: In hot-humid season, dietary supplementation of high dose Chlorophytum borivilianum can effectively reduce stress levels in dairy cows and enhance immunity by downregulating pro-inflammatory and anti-inflammatory cytokine levels.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Article
Pharmacology & Pharmacy
Ruchi Vyas, Kavindra Kumar Kesari, Petr Slama, Shubhadeep Roychoudhury, Rashmi Sisodia
Summary: This study measured the differential expression of antioxidant enzymes in response to radiation-induced oxidative stress after administration of C. borivilianum root extract. The results indicate a significant increase in glutathione levels and the activity of glutathione-related antioxidant enzymes in mice treated with CRE and CRE-AgNPs. The activity of catalase and superoxide dismutase was also increased in the CRE-AgNPs pretreated irradiated groups.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Plant Sciences
Nishant Kaushal, Deepika Verma, Anshu Alok, Ashutosh Pandey, Kashmir Singh
Summary: The overexpression of CbSE increased stigmasterol levels and caused changes in plant morphology. The upregulation of genes upstream and downstream of CbSE confirmed its regulatory role in the saponin biosynthetic pathway.
PLANT CELL REPORTS
(2023)
Article
Cell Biology
Ruchi Vyas, Kavindra Kumar Kesari, Norbert Lukac, Petr Slama, Shubhadeep Roychoudhury, Rashmi Sisodia
Summary: This study evaluated the effect of ethanolic extract of Chlorophytum borivilianum L. (CRE) on sperm maturation against adversities posed by ionizing gamma irradiation. The results showed that CRE exhibited remarkable antioxidant potential and could protect sperm from oxidative stress.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Plant Sciences
Adina I. Gavrila, Christina M. Zalaru, Rodica Tatia, Ana-Maria Seciu-Grama, Cristina L. Negrea, Ioan Calinescu, Petre Chipurici, Adrian Trifan, Ioana Popa
Summary: Hedera helix L. contains beneficial phytochemicals that can be extracted using different methods. This study found that microwave-assisted extraction (MAE) was the most suitable for saponins, while ultrasound-assisted extraction (UAE) was best for carbohydrates and polyphenols. The extracts obtained through UAE exhibited the highest antioxidant activity. The temperature, time, and solvent type used in the extraction process all influenced the extraction efficiency.
Article
Plant Sciences
Jhilmil Nath, Kiran Devi, Vikas Kumar, Palak Sharma, Ram Kumar Sharma, Rohit Joshi
Summary: In this study, the taxonomic and morphological characteristics of Chlorophytum comosum var. comosum were analyzed, and an efficient in vitro propagation system was established. Floral induction and root growth were successfully achieved through the evaluation of different culture media and hormones. This study also reported the in vitro flowering and genetic stability analysis of Chlorophytum comosum var. comosum for the first time. Rating: 8 points.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Biochemistry & Molecular Biology
Chandrasekar Palanichamy, Damodar Nayak Ammunje, Parasuraman Pavadai, Sureshbabu Ram Kumar Pandian, Panneerselvam Theivendren, Shanmugampillai Jeyarajaguru Kabilan, Ewa Babkiewicz, Piotr Maszczyk, Selvaraj Kunjiappan
Summary: This study demonstrates the significant effects of Mimosa pudica Linn. extract on the male sexual system of rats with diabetes, including scavenging excessive free radicals and alleviating the deleterious effects of diabetes. The extract improves body weight, reproductive organ weight, sperm characteristics, and testes histocellular arrangement in rats. Additionally, it increases hormone levels and antioxidant enzymes while reducing oxidative stress markers in both serum and testicular homogenates. In silico molecular docking also predicts high potential compounds in the extract that show binding affinities with the PDE5 receptor. Overall, ethanolic extract of M. pudica L. exhibits significant aphrodisiac performance in diabetic rats.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Food Science & Technology
M. L. Sudha, K. Umashankar, Ashwath K. Kumar, P. Giridhar, P. Prabhasankar
Summary: This study explored the use of Decalepis hamiltonii natural flavour extract in biscuit formulation for the first time. Aqueous and ethanolic extracts, known for their rich flavour metabolites and antioxidant activity, were added to the biscuits at different concentrations. The study found that biscuits made with ethanol extract had a lighter colour, while those made with aqueous extract retained more bioactive compounds. Among the formulations, the biscuit with 1% ethanol extract showed the best sensory attributes and in vitro antioxidant potential.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Horticulture
Saeideh Rostami-Balan, Shirin Dianati Daylami, Soheil Karimi
Summary: Different osmotic pretreatments were investigated to induce tuber formation in D. umbrosa. Results showed that PEG and mannitol 2% pretreatments increased root number and photosynthetic pigments, and induced accumulation of soluble and reserve sugars in tubers.
JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY
(2022)
Article
Plant Sciences
Shailendra Gurav, Manish Wanjari, Ritesh Bhole, Nishikant Raut, Satyendra Prasad, Suprit Saoji, Rupesh Chikhale, Pukar Khanal, Amit Pant, Muniappan Ayyanar, Nilambari Gurav
Summary: This study confirms the aphrodisiac potential of Ashwagandha ghrita (AG) through bioinformatics and experimental approaches. It also demonstrates the positive effects of AG on reproductive organs and its interaction with phosphodiesterase-5.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Palanisamy Prakash, Nisha Kumari, Ekambaram Gayathiri, Kuppusamy Selvam, Manikavali Gurunadhan Ragunathan, Murugesan Chandrasekaran, Munirah Abdullah Al-Dosary, Ashraf Atef Hatamleh, Ashok Kumar Nadda, Manu Kumar
Summary: The plant extracts from AT demonstrate various pharmacological activities such as antioxidant, antibacterial, and anti-inflammatory properties, making them suitable for cancer treatment.
Article
Chemistry, Multidisciplinary
Mai Dinh Tri, Nguyen Tan Phat, Phan Nhat Minh, Mai Thanh Chi, Bui Xuan Hao, Tran Nguyen Minh An, Mahboob Alam, Nguyen Van Kieu, Van-Son Dang, Tran Thi Ngoc Mai, Thuc-Huy Duong
Summary: Four triterpenes, including two new triterpenes recurvatanes A and B, were isolated from the aerial parts of Mussaenda recurvata. The chemical structures of the compounds were identified through spectroscopic data and literature comparison. Compounds 1 and 2 showed moderate inhibitory activity on NO production in LPS-stimulated RAW264.7 cells.
Article
Agriculture, Dairy & Animal Science
Pooja Devi, Mahendra Singh, Rita Mehla, Ajithakumar H M
Summary: The study demonstrated that supplementation of 80 mg/kg BW/day of C. borivilianum during hot and humid season increased milk production, decreased saturated fatty acids, and improved mammary health and milk quality in dairy cows.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Article
Biochemistry & Molecular Biology
Mater H. Mahnashi, Waqas Alam, Mohammed A. Huneif, Alqahtani Abdulwahab, Mohammed Jamaan Alzahrani, Khaled S. Alshaibari, Umar Rashid, Abdul Sadiq, Muhammad Saeed Jan
Summary: Diabetes mellitus is a life-threatening disorder, and compound 3 showed excellent inhibitory effects in treating diabetes by targeting multiple enzymes and proteins. It also exhibited antioxidant activity and proved to be safe and effective in mice.
Article
Reproductive Biology
Renner Philipe Rodrigues Carvalho, Graziela Domingues de Almeida Lima, Fernanda Carolina Dias Ribeiro, Luiz Otavio Guimaraes Ervilha, Elizabeth Lopes Oliveira, Arabela Guedes Azevedo Viana, Mariana Machado-Neves
Summary: Eugenol has an impact on reproductive parameters of rats, with 20 and 40 mg kg(-1) of eugenol reducing serum testosterone levels, and the highest dose altering lactate and glucose concentrations in the epididymis. Moreover, all eugenol concentrations modify oxidative parameters in male organs by diminishing CAT activity and increasing FRAP and CAT activity.
REPRODUCTIVE TOXICOLOGY
(2022)
Review
Pathology
Nikunj Tandel, Anish Z. Joseph, Aishwarya Joshi, Priya Shrama, Ravi P. N. Mishra, Rajeev K. Tyagi, Prakash S. Bisen
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2020)
Article
Nutrition & Dietetics
Anish Zacharia, Daniel Saidemberg, Chanchal Thomas Mannully, Natalya M. Kogan, Alaa Shehadeh, Reut Sinai, Avigail Zucker, Reut Bruck-Haimson, Nir Goldstein, Yulia Haim, Christian Dani, Assaf Rudich, Arieh Moussaieff
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2020)
Article
Biochemistry & Molecular Biology
Albert Batushansky, Anish Zacharia, Alaa Shehadeh, Reut Bruck-Haimson, Daniel Saidemberg, Natalya M. Kogan, Chanchal Thomas Mannully, Shmuel Herzberg, Assaf Ben-Meir, Arieh Moussaieff
Article
Oncology
Irfana Zahoor, Farhat Jan, Ujjawal Sharma, Kiran K. Sahu, Amita Sharma, Shalini Pareek, Divya Shrivastava, Prakash S. Bisen
Summary: This study successfully synthesized silver nanoparticles using aqueous leaf-extract of Viburnum nervosum, showcasing the potential for anti-cancer applications. Results indicated promising anti-cancer properties of the synthesized silver nanoparticles, highlighting their advantages over traditional nanoparticle formulations.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Moushmi Goswami, Pavni Rekhi, Mousumi Debnath, Seeram Ramakrishna
Summary: Microbial polyhydroxyalkanoates (PHA) are proteinaceous storage granules ranging from 100 nm to 500 nm, produced by unique sources like Bacillus sp. These bioplastics can be enhanced by adding functional groups for industrial use, such as in nanocomposites with hydroxyapatite for improved mechanical and thermal properties. PHA can be utilized in various industries as nanofillers or drug carriers, and also for fabricating bone scaffolds using different strategies for bone regeneration.
Review
Biochemistry & Molecular Biology
Debabrata Majumder, Mousumi Debnath, Kamal Nayan Sharma, Surinder Singh Shekhawat, G. B. K. S. Prasad, Debasish Maiti, Seeram Ramakrishna
Summary: The Mediterranean diet is highly regarded and is associated with the prevention of degenerative diseases and increased longevity. Olive oil consumption is a key feature of this diet, and it is rich in bioactive compounds that have anti-inflammatory and cardioprotective properties. Recent studies suggest that the phytochemicals in olive oil may have potential against SARS-CoV-2. However, there are still gaps in understanding how the phytochemical composition of olive oil is influenced by processing methods and the signaling pathways involved in its health benefits.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2022)
Article
Environmental Sciences
Debabrata Majumder, Rahul Debnath, Priyatosh Nath, K. V. Libin Kumar, Mousumi Debnath, Prosun Tribedi, Debasish Maiti
Summary: Lung cancer, the most aggressive and deadly form of cancer, is directly linked to smoking. The combination treatment of ethanolic olive leaf extract and bromelain can synergistically reduce lung cancer incidence by reducing inflammation and oxidative stress, regulating the expression of inflammatory markers, and modulating pulmonary antioxidant activity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Biotechnology & Applied Microbiology
Pavni Rekhi, Moushmi Goswami, Seeram Ramakrishna, Mousumi Debnath
Summary: Polymers are essential in modern living, but those with a large carbon footprint are increasingly seen as harmful to the environment. Polyhydroxyalkanoate (PHA) is regarded as a potential alternative derived from microbial biopolymer. PHA shows promise for various applications, particularly in the medical sector due to its biodegradability and biocompatibility.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Mukesh Tanwar, Mousumi Debnath, Sharmista Debnath, Priyanka Sharma, Anoop Mukhopadhay, Nipun Kakar, Seeram Ramakrishna
Summary: Extremophilic microbial proteases are valuable sources of detergent additives due to their stability and activity. Immobilization techniques can improve product yield and stability, making them ideal for use in laundry detergents.
JOURNAL OF CLEANER PRODUCTION
(2022)
Review
Nutrition & Dietetics
Smita Sisodiya, Aditya Sinha, Mousumi Debnath, Rajveer Shekhawat, Surinder Singh Shekhawat
Summary: This study highlights the importance of applying image processing techniques for early detection and classification of diseases in olive plants. Infections in olives can cause significant losses and low olive oil yields, therefore, early detection of disease infestations is crucial to protect olive plants and their yield.
CURRENT NUTRITION & FOOD SCIENCE
(2022)
Article
Chemistry, Applied
Priyanka Sharma, Pavni Rekhi, Sapna Kumari, Mousumi Debnath
Summary: The Sambhar Salt Lake in Rajasthan, India provides a unique opportunity for studying halophilic microorganisms that produce surfactins with industrial applications. Through comparative genomics and chemotaxonomic research, the relationship between Bacillus species was explored. The presence of nonribosomal protein sequences (NRPS) confirmed the existence of surfactin-type lipopeptide biosurfactants. Structural investigation revealed similarities in the biosurfactants produced by Bacillus haynesii strain SAII and Bacillus swezeyi strain SEIII. The biosurfactants extracted from these microorganisms showed potential for bioremediation of contaminants, as shown by their high recovery rate of oil from contaminated sand.
JOURNAL OF SURFACTANTS AND DETERGENTS
(2022)
Article
Chemistry, Multidisciplinary
Sapna Kumari, Mousumi Debnath, Shirish Hari Sonawane, Surya Teja Malkapuram, Murali Mohan Seepana
Summary: Textile industries monopolize the use of synthetic and natural colors, which have disastrous repercussions when released into the environment. A study successfully isolated a biosurfactant-producing bacterium from textile effluent-contaminated soil and found that it has the potential to degrade dyes. This research is significant for wastewater treatment in textile industries.
Article
Chemistry, Multidisciplinary
Priyanka Sharma, Pavni Rekhi, Mousumi Debnath
Summary: This study investigates the application of halophilic biosurfactant-producing bacteria for removing pollutants from textile effluent. The strain SE I of Staphylococcus sciuri subsp. rodentium, isolated from Sambhar Salt Lake in Rajasthan, showed high emulsification activity and reduced surface tension. It also exhibited the potential to remove heavy metals and decolorize dyes. The surfactin biosurfactant extracted from this strain can be an alternative biosorbent and bioremediation agent.
Article
Education & Educational Research
Falguni Singh, Monika Saini, Ashish Kumar, Seeram Ramakrishna, Mousumi Debnath
Summary: This study used the Dundee Ready Education Environment Measure (DREEM) to examine the impact of the educational environment on students' perceptions of learning and teaching in a university offering higher education. The findings showed that students were generally satisfied with the student-teaching environment. The validity of the DREEM was verified through factor analysis and statistical analysis. The study proposed that a redesigned DREEM could be valuable for assessing the educational environment at institutions providing higher education.
LEARNING ENVIRONMENTS RESEARCH
(2023)
Article
Integrative & Complementary Medicine
Ravindra Verma, Vaibhav Misra, Dileep Tiwari, Prakash S. Bisen
Summary: Many environmental risk factors are associated with chronic inflammation. The first case of coronavirus was reported in India on 30th January 2020. India has the potential to deal with the coronavirus outbreak due to its climatic conditions and high immunity of its people. Herbal medicine has the potential to enhance immunity for preventing COVID-19, but further clinical trials are needed to determine the proper dosage and timing for interventions.
CURRENT TRADITIONAL MEDICINE
(2021)