Article
Critical Care Medicine
Jacob A. Davis, Anne C. Bopp, Melissa K. Henwood, Paris Bean, James W. Grau
Summary: Research has shown that engaging pain pathways after spinal cord injury (SCI) worsens secondary injury and impairs locomotor recovery. It is significant because SCI often involves additional tissue damage (polytrauma) that activates pain activity. Blocking pain-induced hemorrhage can be achieved by surgical transection or pharmacological transection of the cord. This study suggests that inhibiting brain activity via anesthetic drugs can offer protection against pain-induced inflammation and hemorrhage in SCI.
JOURNAL OF NEUROTRAUMA
(2023)
Review
Clinical Neurology
Ryota Kimura, Norio Yamamoto, Jun Watanabe, Yuichi Ono, Michio Hongo, Naohisa Miyakoshi
Summary: This study compared the efficacy and safety of ultrasound-guided spinal nerve injections with fluoroscopic or CT-guided spinal nerve injections. The results showed that ultrasound-guided injections had similar pain reduction compared to traditional methods, but they reduced major adverse events, decreased procedure time, and possibly reduced minor adverse events. There was probably no significant difference in the change in functional disability score between the two methods.
EUROPEAN SPINE JOURNAL
(2023)
Article
Anesthesiology
Nigel Wilkinson-Maitland, Aaron J. Cunningham, Mohammad Esfahanian
Summary: BackgroundExternal Oblique Intercostal (EOI) fascial plane blockade is a technique for regional anesthesia in upper abdominal surgeries. This case study presents a successful alternative for analgesic management in a neonate undergoing Kasai portoenterostomy using bilateral EOI block catheters, with comparable outcomes to epidural analgesia.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Emergency Medicine
Meghan Kelly Herbst, Ryan Sorkin
Summary: This article reports the first use of ultrasound-guided spinal accessory nerve block for acutely treating trapezius myofascial pain in the Emergency Department. The technique proved feasible and offered substantial therapeutic benefit for patients with intractable trapezius pain.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Review
Anesthesiology
David H. Kim, Sang Jo Kim, Jiabin Liu, Jonathan Beathe, Stavros G. Memtsoudis
Summary: This article discusses the concepts and potential mechanisms of fascial plane blocks (FPBs), as well as the major FPBs of the extremities, posterior torso, and anterior torso. It includes characteristics, indications, and a brief summary of the literature on these blocks, with an estimate of the overall level of evidence supporting individual approaches as FPBs continue to rapidly evolve.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2021)
Article
Anesthesiology
Marie Sorenstua, Ann-Chatrin Linqvist Leonardsen, Ki Jinn Chin
Summary: Since 2016, the erector spinae plane block (ESPB) has been widely used as a regional anesthetic technique. However, there is ongoing controversy over the mechanism of action of ESPB. This paper reviews the spread of local anesthetic to different neural structures and the potential role of the dorsal root ganglion (DRG) in ESPB and other intertransverse process blocks.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Anesthesiology
Ki Jinn Chin, Barbara Versyck, Hesham Elsharkawy, Maria Fernanda Rojas Gomez, Xavier Sala-Blanch, Miguel A. Reina
Summary: Fascial plane blocks are regional anesthesia techniques that target the space between two fascial layers for analgesia. Understanding the musculofascial anatomy and nerves involved in innervation can aid in sonographic landmark identification and local anesthetic spread. This knowledge is crucial for improving the clinical utility, efficacy, and safety of FPBs.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2021)
Article
Clinical Neurology
Timothy Chryssikos, Jesse A. Stokum, Abdul-Kareem Ahmed, Chixiang Chen, Aaron Wessell, Gregory Cannarsa, Nicholas Caffes, Jeffrey Oliver, Joshua Olexa, Phelan Shea, Mohamed Labib, Graeme Woodworth, Alexander Ksendzovsky, Uttam Bodanapally, Kenneth Crandall, Charles Sansur, Gary Schwartzbauer, Bizhan Aarabi
Summary: Real-time intraoperative ultrasound (IOUS) can be used as a supplement to postoperative MRI and CT myelography for the assessment of spinal cord decompression.
Review
Anesthesiology
Adrian Bosenberg
Summary: The erector spinae plane block (ESPB) is widely used in children and has been shown to be safe and effective. The mechanism of the spread of local anesthetic is still controversial, and anatomical differences in children may explain the variability in spread.
PEDIATRIC ANESTHESIA
(2023)
Article
Cell Biology
Pei Yu, Kai Yang, Min Jiang
Summary: Nerve regeneration after spinal cord injury is regulated by many factors, including the distribution changes of RXR alpha in neurons and the upregulation of p66shc expression. RXR alpha inhibits nerve regeneration by promoting p66shc expression, and intervention of RXR alpha or p66shc can promote functional recovery after spinal cord injury.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2021)
Article
Medicine, General & Internal
Nicole C. McCoy, Ellen L. Hay, Deborah A. Romeo, J. Wesley Doty, Bethany J. Wolf, Michelle P. Hudspeth
Summary: This study aimed to investigate the application of preoperative bilateral quadratus lumborum blocks and a standardized perioperative analgesic protocol in bone marrow harvesting. The results showed that implementing this protocol significantly reduced the amount of perioperative opioid consumption without compromising immediate postoperative pain control.
FRONTIERS IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ahmed A. A. Bessar, Mohamed M. Arnaout, Mohammad Abd Alkhalik Basha, Shady E. Shaker, Ashraf E. Elsayed, Manar Awad Bessar
Summary: The study compared CT and fluoroscopic-guided sacroiliac joint injections in terms of pain relief, radiation doses, and patient satisfaction, with CT guidance showing favorable outcomes in long-term pain relief.
INSIGHTS INTO IMAGING
(2021)
Article
Anesthesiology
Beth Molloy, Thomas Baum, Sebastian Eves-van den Akker
Summary: Central neuraxial blocks are essential techniques in anesthesia, especially for obstetric, obese, and respiratory-compromised patients. Traditional anatomical landmark-based approaches have limitations, and ultrasound-guided techniques have emerged as a new option for central neuraxial blocks.
BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY
(2023)
Article
Veterinary Sciences
Jiyoung Kim, Dalhae Kim, Donghwi Shin, Taehoon Sung, Suehyung Rhee, Minha Kim, Changhun Nam, Inhyung Lee, Won-Gyun Son
Summary: This study compared the duration of regional anesthesia of the pelvic limb using bupivacaine with and without a temperature-responsive hydrogel in dogs. The results showed that the use of the hydrogel extended the duration of the anesthesia.
VETERINARY MEDICINE AND SCIENCE
(2023)
Article
Anesthesiology
Jue Gu, Eerdun Wang, Shiyun Dai, Rong Dong, Fengying Xu, Zijin Shen, Zhiyuan Wang, Xingying He
Summary: Ultrasound-guided multiple nerve blockade may be an alternative for geriatric hip fracture patients, providing satisfactory intraoperative pain management and reducing early postoperative cognitive disorders.
CLINICAL JOURNAL OF PAIN
(2021)