Journal
CURRENT ORGANIC CHEMISTRY
Volume 16, Issue 4, Pages 451-482Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527212799499840
Keywords
Oxiranes; Enantioselectivity; Enantioconvergence; Kinetic Resolution; Desymmetrization; Asymmetric Synthesis; Biotransformation; Biocatalysis; Vicinal Diol; Chiral Synthon; Building Block
Categories
Funding
- Czech Science Foundation [P207/10/0135, P504/10/0137]
- Institutional Research Concept [AV0Z50200510]
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The number of synthetic applications of epoxide hydrolases in organic chemistry has reached a remarkable level. This has been due to a tremendous amount of work dedicated to the discovery of novel epoxide hydrolases from various biological sources, understanding the structure and function of these widespread enzymes and last but not least, the stabilization of these biocatalysts by various means for production purposes.
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