Editorial Material
Cell Biology
Nadine Martin, Anda Huna, David Bernard
Summary: Cellular senescence plays a critical role in various physiological and pathological contexts. Recent studies have highlighted the dual effects that eliminating senescent endothelial cells can have on health span. This raises questions about the current development of senolytics as a therapeutic strategy.
TRENDS IN CELL BIOLOGY
(2021)
Article
Economics
Mihai Mutascu, Florian Horky, Cristina Strango
Summary: This paper extends Busato et al.'s (2022) model to explore the impact of digitalisation on green preferences. It takes into account environmental shocks, environmental status, quality of green digitalised information, and uncertainty avoidance conditions. The findings indicate that digitalisation can stimulate green preferences in clean environments with distortive green information, while in polluted environments, the digitalisation of non-distortive green information can expand green preferences. The study also highlights the importance of specific factors such as environmental shocks, digitalisation, and the quality of green information in shaping green preferences.
Article
Psychology, Multidisciplinary
Qinglin Zhao, Wenxia Zhou
Summary: The ambivalent leader-follower relationship can have positive or negative influences, depending on the degree of ambivalence, support from the third party, and the integrative complexity of the follower.
FRONTIERS IN PSYCHOLOGY
(2021)
Editorial Material
Hematology
Georg Stary
Summary: In this study published in Blood, van Halteren et al have identified an immune cell signature that is associated with the onset of acute graft-versus-host disease (aGVHD) and the response to first- and second-line therapy.(1)
Review
Neurosciences
Benton Purnell, Madhuvika Murugan, Raja Jani, Detlev Boison
Summary: Adenosine plays both beneficial and detrimental roles in epilepsy. Its benefits include seizure termination, vasodilatory effects, neuroprotection, and antiepileptogenic effects. Detriments include respiratory suppression, contribution to EEG suppression, prolonged increase in extracellular adenosine, excitatory effects via A(2A) receptor activation, and potential contributions to sleep alterations and SUDEP.
FRONTIERS IN NEUROSCIENCE
(2021)
Review
Biodiversity Conservation
L. J. Hansen, K. N. Braddock, D. A. Rudnick
Summary: This study aims to evaluate the effectiveness of adaptation recommendations for conservation in published literature, and discovers a lack of research. The results show a significant shortage of evidence to determine if recommended actions can achieve desired conservation improvements, and a stagnation in the growth of the field.
BIOLOGICAL CONSERVATION
(2023)
Editorial Material
Endocrinology & Metabolism
Rachel A. M. Heutz, Ralf W. J. Weijs, Rianne A. A. de Heus, Jurgen A. H. R. Claassen
Summary: We discussed the current evidence of antihypertensive treatment in people with dementia, exploring both the potential benefits and harms. Our conclusion is that there is insufficient evidence to support the claim of an increased risk of cerebral hypoperfusion with antihypertensive treatment in dementia, and there is growing evidence contradicting this claim.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Editorial Material
Immunology
Shiv Pillai
Summary: Repeated doses of mRNA vaccines for COVID-19 result in an increase of IgG4 antibodies, which can neutralize the virus and form mixed immune complexes with IgG1. However, pure IgG4 may be less effective than IgG1 or IgG3 antibodies in facilitating opsonization and eliminating infected cells.
SCIENCE IMMUNOLOGY
(2023)
Editorial Material
Endocrinology & Metabolism
Lucy Beishon, Victoria J. Haunton, Ronney B. Panerai
Summary: Hypertension and dementia are closely related, but the optimal blood pressure targets for dementia remain unclear. Both high and low blood pressure are associated with poorer cognition. The changes in vascular physiology in dementia may increase the risk of cerebral hypoperfusion associated with antihypertensives. Therefore, individualized blood pressure targets should be the focus for antihypertensive therapy in dementia.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Article
Endocrinology & Metabolism
Ananya Nandy, Elizabeth Rendina-Ruedy
Summary: Skeletal remodeling is essential for maintaining bone mass, closely tied to whole body metabolism. The interaction of bone cells is crucial, and disruptions can lead to osteoporosis and fractures.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Review
Oncology
Yihao Liao, Mengyue Yang, Keke Wang, Youzhi Wang, Boqiang Zhong, Ning Jiang
Summary: OTUB1 is the most important element of the deubiquitinase OTU superfamily, and it regulates immune response, cancer progression, and immune diseases by deubiquitinating and stabilizing related proteins. Understanding the role and regulatory axis of OTUB1 is crucial for exploring the balance between immune response and defense and restraining cancer progression.
Article
Business
Sumit Agarwal, Yanhao Ding, Weida Kuang, Xiao Zhu
Summary: This paper examines the impact of environmental punishments on housing prices through information disclosure and dissemination. The research finds that the transaction prices of houses near environmentally punished firms decrease on average by 1.84%, with multiple punishments amplifying the negative effects. The effects are particularly pronounced during heating seasons and national important events. Unfortunately, there is little evidence of environmental punishments in the rental housing market. The study identifies three mechanisms of the impact: information disclosure, information dissemination, and health concerns.
JOURNAL OF ENVIRONMENTAL ECONOMICS AND MANAGEMENT
(2023)
Review
Oncology
Zhuo Georgia Chen, Nabil F. Saba, Yong Teng
Summary: FAT1, one of the most frequently mutated genes in cancer, has potential as a target or prognostic biomarker in cancer treatment. Its function in cancer progression seems to be cancer-type specific and requires further clarification. This review summarizes the recent literature on the role of FAT1 in cancer, including its involvement in cell-cell contact, mitochondrial respiration, and epithelial-mesenchymal transition.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
(2022)
Review
Cell Biology
Sarah-Eve Lemay, Charifa Awada, Tsukasa Shimauchi, Wen-Hui Wu, Sebastien Bonnet, Steeve Provencher, Olivier Boucherat
Summary: Pulmonary arterial hypertension is a debilitating chronic disorder that puts pressure overload on the heart, leading to structural and functional changes, ultimately causing heart failure and death. Recent research suggests that overactivation of fetal genes may play a critical role in the process of pulmonary arterial hypertension, exploring whether this discovery is a causative factor or a protective mechanism.
Article
Business, Finance
Jie He, Luling He, Kam C. Chan
Summary: The literature suggests that controlling shareholders tend to expropriate minority shareholders, while the military background of CEOs appears to mitigate such behavior. The study finds that firms led by CEOs with military experience engage in less tunneling. Additionally, this effect is more pronounced for companies with larger controlling shareholders, no seasoned equity offering plans, non-Big Four accounting firms as auditors, or fewer analysts tracking them. Interestingly, military CEO firms not only have less expropriation but also exhibit higher firm value, lower perks consumption, and more positive media coverage. However, military CEOs are also more likely to face dismissal. This evidence challenges the assumption that CEOs, especially those with military background, always align with controlling shareholders in expropriating minority shareholders.
RESEARCH IN INTERNATIONAL BUSINESS AND FINANCE
(2023)