Article
Medicine, General & Internal
Felix J. Krendl, Franka Messner, Claudia Boesmueller, Stefan Scheidl, Benno Cardini, Thomas Resch, Annemarie Weissenbacher, Rupert Oberhuber, Manuel Maglione, Stefan Schneeberger, Dietmar Oefner, Christian Margreiter
Summary: The study evaluated the incidence and impact of post-transplant malignancies (PTMs) following pancreas transplantation, with skin cancers being the most common type. Patients with solid organ and hematologic malignancies had a significantly higher risk of death compared to those with skin cancers following pancreas transplantation.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Marjolein Leemkuil, Franka Messner, Stan Benjamens, Felix J. Krendl, Henri G. D. Leuvenink, Christian Margreiter, Robert A. Pol
Summary: This study retrospectively analyzed 317 pancreas transplants and found that pancreas donor extraction time was not associated with graft survival, but had a significant impact on postoperative complications occurrence.
Article
Immunology
Raphael Porret, Raphael P. H. Meier, Josip Mikulic, Manuel Pascual, Vincent Aubert, Thomas Harr, Dela Golshayan, Yannick D. D. Muller, Swiss Transplant Cohort Study
Summary: The study found that atopy is associated with better long-term patient and graft survival after kidney transplantation, independently of age and living donor donation. However, it does not affect the occurrence of acute rejection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Endocrinology & Metabolism
Enrique Montagud-Marrahi, Antonio J. Amor, Alicia Molina-Andujar, David Cucchiari, Ignacio Revuelta, Nuria Esforzado, Frederic Cofan, Federic Oppenheimer, Vicens Torregrosa, Joaquim Casals, Joana Ferrer, Enric Esmatjes, Maria Jose Ramirez-Bajo, Mireia Musquera, Beatriu Bayes, Josep M. Campistol, Fritz Diekmann, Pedro Ventura-Aguiar
Summary: The study found that there was no significant difference in pancreas graft survival between recipients from donors who received insulin therapy before donation and those who didn't. Pre-donation insulin therapy did not appear to impact transplant outcomes in terms of surgical complications, recipient death, and pancreas graft failure.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Review
Gastroenterology & Hepatology
Jonathan E. H. Ling, Timothy Coughlan, Kevan R. Polkinghorne, John Kanellis
Summary: This study systematically reviewed risk indices in solid pancreas transplantation and found that most indices have not been externally validated. PDRI and P-PASS are the only externally validated risk indices associated with solid pancreas transplantation outcomes.
BMC GASTROENTEROLOGY
(2021)
Article
Surgery
Haley M. Gonzales, David J. Taber, Satish Nadig, Neha Patel, Angello Lin, Prabhakar K. Baliga, Vinayak S. Rohan
Summary: This study reveals significant health disparities among African American pancreas transplant recipients, including poorer glycemic control and higher early mortality rates, despite similar long-term survival.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Immunology
Bartlomiej J. Witczak, Soren E. Pischke, Anna Reisaeter, Karsten Midtvedt, Judith K. Ludviksen, Kristian Heldal, Trond Jenssen, Anders Hartmann, Anders Asberg, Tom E. Mollnes
Summary: Early complement activation, assessed by plasma TCC levels, is associated with impaired long-term patient and graft survival.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Medicine, General & Internal
Hans-Michael Hau, Nora Jahn, Sebastian Rademacher, Elisabeth Sucher, Jonas Babel, Matthias Mehdorn, Andri Lederer, Daniel Seehofer, Uwe Scheuermann, Robert Sucher
Summary: The study demonstrates that pancreatic implantation prior to kidney implantation in simultaneous pancreas-kidney transplantation has an impact on the early-post-operative outcomes and survival rates of pancreas grafts, but does not significantly affect kidney graft survival rates.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Carlos Ortiz-Bautista, Javier Muniz, Luis Almenar-Bonet, Maria G. Crespo-Leiro, Jose M. Sobrino-Marquez, Marta Farrero-Torres, Maria D. Garcia-Cosio, Beatriz Diaz-Molina, Isabel Zegri-Reiriz, Francisco Gonzalez-Vilchez, Zorba Blazquez-Bermejo, Amador Lopez Granados, Manuel Gomez-Bueno, Luis de la Fuente-Galan, Teresa Blasco-Peiro, Iris P. Garrido-Bravo, Elena Garcia-Romero, Gregorio Rabago Juan-Aracil, Luis Garcia-Guereta, Juan F. Delgado-Jimenez
Summary: The IMPACT score failed to accurately predict the risk of death after heart transplantation in a contemporary Spanish cohort.
CLINICAL TRANSPLANTATION
(2022)
Article
Surgery
Dae Gon Ryu, Dae Hwan Kang, Cheol Woong Choi, Byung Hyun Choi, Hyung Wook Kim, Su Bum Park, Su Jin Kim, Hyeong Seok Nam
Summary: Endoscopic examination can visualize graft failure in PT patients, while diffuse erythema inside the graft duodenum may be a sign of acute rejection.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Branden D. Tarlow, W. Ray Kim, Ajitha Mannalithara, Paul Y. Kwo, C. Andrew Bonham, Allison Kwong
Summary: This study found that MELD 3.0 scores beyond 40 are associated with increasing waitlist mortality without adversely affecting posttransplant outcomes. Uncapping the MELD score for waitlist candidates may lead to greater survival benefits from liver transplantation.
Article
Geriatrics & Gerontology
Zoltan Czigany, Wiebke Kramp, Isabella Lurje, Hannah Miller, Jan Bednarsch, Sven Arke Lang, Tom Florian Ulmer, Philipp Bruners, Pavel Strnad, Christian Trautwein, Martin Wolfgang von Websky, Frank Tacke, Ulf Peter Neumann, Georg Lurje
Summary: Myosteatosis is an important prognostic marker in patients undergoing deceased donor liver transplantation, particularly in the early post-operative phase. Low skeletal muscle mass alone is not significantly associated with graft and patient survival. Preoperative myosteatosis may be crucial for predicting outcomes in OLT recipients.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Surgery
Liise K. Kayler, Jing Nie, Katia Noyes
Summary: The study found that the hardest-to-place kidneys accepted later in the match run were associated with higher rates of delayed graft function and graft failure.
AMERICAN JOURNAL OF TRANSPLANTATION
(2021)
Article
Surgery
Verner Eerola, Ville Sallinen, Marko Lempinen, Ilkka Helantera
Summary: A longer procurement interval is associated with improved long-term outcomes in pancreas transplantation, as it is correlated with increased death-censored graft survival and decreased acute rejections. This study analyzed the association between procurement interval and pancreas graft outcomes using multivariable models. The results showed that a longer procurement interval is beneficial for pancreas transplantation.
TRANSPLANT INTERNATIONAL
(2023)
Article
Medicine, General & Internal
Naohiro Aida, Taihei Ito, Kei Kurihara, Izumi Hiratsuka, Megumi Shibata, Atsushi Suzuki, Takashi Kenmochi
Summary: The reconstruction of the common hepatic artery in pancreas transplantation does not significantly impact patient and graft survival rates and endocrine functions. Common hepatic artery reconstruction is not essential unless there is a risk of ischemia.
JOURNAL OF CLINICAL MEDICINE
(2022)