Pharmacological manipulation of dendritic cells in the pursuit of transplantation tolerance

Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts

(2011) T. Yamano et al.   BLOOD

Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells

(2011) Kyung-Dal Choi et al.   Nature Protocols

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis

(2010) R. A. Harry et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

(2010) Jeroen N. Stoop et al.   ARTHRITIS AND RHEUMATISM

GM-CSF induces bone marrow precursors of NOD mice to skew into tolerogenic dendritic cells that protect against diabetes

(2010) Simon Gaudreau et al.   CELLULAR IMMUNOLOGY

Curcumin induces maturation-arrested dendritic cells that expand regulatory T cells in vitro and in vivo

(2010) N. M. Rogers et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation

(2010) Liat Bar-On et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human dendritic cell antigen presentation and chemotaxis are inhibited by intrinsic 25-hydroxy vitamin D activation

(2010) Lars E. Bartels et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tolerogenic Dendritic Cells Generated with Different Immunosuppressive Cytokines Induce Antigen-Specific Anergy and Regulatory Properties in Memory CD4 + T Cells

(2010) Honorio Torres-Aguilar et al.   JOURNAL OF IMMUNOLOGY

Differential Modulation of TLR3- and TLR4-Mediated Dendritic Cell Maturation and Function by Progesterone

(2010) L. A. Jones et al.   JOURNAL OF IMMUNOLOGY

A Versatile Role of Mammalian Target of Rapamycin in Human Dendritic Cell Function and Differentiation

(2010) M. Haidinger et al.   JOURNAL OF IMMUNOLOGY

Prevention of Acute and Chronic Allograft Rejection by Combinations of Tolerogenic Dendritic Cells

(2010) Y. L. Huang et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

(2010) Shoba Amarnath et al.   PLOS BIOLOGY

Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells

(2010) Hyun-Jin Kim et al.   Immune Network

ORIGINAL ARTICLE: Impact of Female Sex Hormones on the Maturation and Function of Human Dendritic Cells

(2009) Sabine E. Segerer et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Phenotypic and functional markers for 1α,25-dihydroxyvitamin D3-modified regulatory dendritic cells

(2009) A. W. Pedersen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Transplantation tolerance in an age of induced pluripotency

(2009) Paul J Fairchild   Current Opinion in Organ Transplantation

Semi-mature DC are immunogenic and not tolerogenic when inoculated at a high dose in collagen-induced arthritis mice

(2009) Dae-Seog Lim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of Treg by monocyte-derived DC modulated by vitamin D3or dexamethasone: Differential role for PD-L1

(2009) Wendy W. J. Unger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation

(2009) Urban Švajger et al.   IMMUNOLOGY

Comparative effects of aspirin and NO-releasing aspirins on differentiation, maturation and function of human monocyte-derived dendritic cells in vitro

(2009) Biljana Bufan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell–derived lin–CD34+CD43+CD45+ progenitors

(2009) Kyung-Dal Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

TLR Triggering on Tolerogenic Dendritic Cells Results in TLR2 Up-Regulation and a Reduced Proinflammatory Immune Program

(2009) S. Chamorro et al.   JOURNAL OF IMMUNOLOGY

Tryptophan Deprivation Induces Inhibitory Receptors ILT3 and ILT4 on Dendritic Cells Favoring the Induction of Human CD4+CD25+ Foxp3+ T Regulatory Cells

(2009) M. Brenk et al.   JOURNAL OF IMMUNOLOGY

Ig-Like Transcript 3 Regulates Expression of Proinflammatory Cytokines and Migration of Activated T Cells

(2009) C.-C. Chang et al.   JOURNAL OF IMMUNOLOGY

IFN- , as Secreted during an Alloresponse, Induces Differentiation of Monocytes into Tolerogenic Dendritic Cells, Resulting in FoxP3+ Regulatory T Cell Promotion

(2009) A. Eljaafari et al.   JOURNAL OF IMMUNOLOGY

The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells

(2009) J. M. Wilson et al.   JOURNAL OF IMMUNOLOGY

Ly6Clow Monocytes Differentiate into Dendritic Cells and Cross-Tolerize T Cells through PDL-1

(2009) Y. Peng et al.   JOURNAL OF IMMUNOLOGY

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY

Toll-like receptor 2–dependent induction of vitamin A–metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity

(2009) Santhakumar Manicassamy et al.   NATURE MEDICINE

Generation of immunogenic dendritic cells from human embryonic stem cells without serum and feeder cells

(2009) Su-Yi Tseng et al.   Regenerative Medicine

Regulation of Rat and Human T-Cell Immune Response by Pharmacologically Modified Dendritic Cells

(2009) Henrieta Fazekasova et al.   TRANSPLANTATION

Mycophenolic Acid Impedes the Antigen Presenting and Lymph Node Homing Capacities of Human Blood Myeloid Dendritic Cells

(2009) Vito R. Cicinnati et al.   TRANSPLANTATION

Composite Tissue Allotransplantation: Current Challenges

(2009) K.V. Ravindra et al.   TRANSPLANTATION PROCEEDINGS

Toll-Like Receptor 6 Drives Differentiation of Tolerogenic Dendritic Cells and Contributes to LcrV-Mediated Plague Pathogenesis

(2008) R. William DePaolo et al.   Cell Host & Microbe

Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells

(2008) Amy E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells

(2008) A. E. Anderson et al.   JOURNAL OF LEUKOCYTE BIOLOGY