Genetics of Parkinsonʼs disease and essential tremor

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

LINGO1gene analysis in Parkinson's disease phenotypes

(2011) Oswaldo Lorenzo-Betancor et al.   MOVEMENT DISORDERS

LINGO1 Variants in the French-Canadian Population

(2011) Cynthia V. Bourassa et al.   PLoS One

Genetic analysis of “leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1 (LINGO1)” in two independent Chinese parkinson's disease populations

(2010) Yih-Ru Wu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Parkinson’s disease and cancer risk: a systematic review and meta-analysis

(2010) Archna Bajaj et al.   CANCER CAUSES & CONTROL

Replication of the LINGO1 gene association with essential tremor in a North American population

(2010) Lorraine N Clark et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

LINGO1 polymorphisms are associated with essential tremor in Europeans

(2010) Sandra Thier et al.   MOVEMENT DISORDERS

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

(2010) Stephan Gehrke et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

(2010) Yingrui Li et al.   NATURE GENETICS

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease

(2010) Carles Vilariño-Güell et al.   NEUROGENETICS

A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2

(2010) D. M. Kay et al.   NEUROLOGY

Screening for two SNPs of LINGO1 gene in patients with essential tremor or sporadic Parkinson's disease in Chinese population

(2010) Xing Zuo et al.   NEUROSCIENCE LETTERS

Analysis of LINGO1 (rs9652490) polymorphism in sporadic Parkinson's disease in a Polish population, and a meta-analysis

(2010) Monika Białecka et al.   NEUROSCIENCE LETTERS

LINGO1 rs9652490 variant in Parkinson disease patients

(2010) Yi Guo et al.   NEUROSCIENCE LETTERS

The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway

(2010) Angela C. Poole et al.   PLoS One

Mitophagy: the latest problem for Parkinson's disease

(2010) Cristofol Vives-Bauza et al.   TRENDS IN MOLECULAR MEDICINE

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Relative contribution of simple mutations vs. copy number variations in five Parkinson disease genes in the Belgian population

(2009) Karen Nuytemans et al.   HUMAN MUTATION

LRRK2gene variation and its contribution to Parkinson disease

(2009) Coro Paisán-Ruiz   HUMAN MUTATION

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

(2009) Ruben K. Dagda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Risk of incident Parkinson's disease and parkinsonism in essential tremor: a population based study

(2009) J Benito-Leon et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Role of LINGO1 polymorphisms in Parkinson's disease

(2009) Dietrich Haubenberger et al.   MOVEMENT DISORDERS

Variant in the sequence of the LINGO1 gene confers risk of essential tremor

(2009) Hreinn Stefansson et al.   NATURE GENETICS

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

LINGO1 VARIANT INCREASES RISK OF FAMILIAL ESSENTIAL TREMOR

(2009) E. -K. Tan et al.   NEUROLOGY

Parkin dosage mutations have greater pathogenicity in familial PD than simple sequence mutations

(2009) N. Pankratz et al.   NEUROLOGY

Frequency of heterozygous Parkin mutations in healthy subjects: Need for careful prospective follow-up examination of mutation carriers

(2009) Norbert Brüggemann et al.   PARKINSONISM & RELATED DISORDERS

Dopamine receptor D3 gene and essential tremor in large series of German, Danish and French patients

(2008) Delia Lorenz et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

DRD3 Ser9Gly variant is not associated with essential tremor in a series of Italian patients

(2008) C. Vitale et al.   EUROPEAN JOURNAL OF NEUROLOGY

Case-control study of patients with essential tremor in Latvia

(2008) I. Inashkina et al.   EUROPEAN JOURNAL OF NEUROLOGY

LINGO-1 and its role in CNS repair

(2008) Sha Mi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Molecular biology changes associated with LRRK2 mutations in Parkinson's disease

(2008) Yi Wei Lu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Reappraisal of the role of the DRD3 gene in essential tremor

(2008) Marcia A. Blair et al.   PARKINSONISM & RELATED DISORDERS

The PINK1/Parkin pathway regulates mitochondrial morphology

(2008) A. C. Poole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

(2008) H. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Further evidence of genetic heterogeneity in familial essential tremor

(2007) Paolo Aridon et al.   PARKINSONISM & RELATED DISORDERS