Article
Physics, Multidisciplinary
Darren J. Batey, Frederic Van Assche, Sander Vanheule, Matthieu N. Boone, Andrew J. Parnell, Oleksandr O. Mykhaylyk, Christoph Rau, Silvia Cipiccia
Summary: This experiment demonstrated the successful application of X-ray ptychography in a small-scale laboratory setting, showcasing the potential for high-resolution phase contrast imaging to be performed at small-scale sources worldwide.
PHYSICAL REVIEW LETTERS
(2021)
Article
Materials Science, Multidisciplinary
Cyril Besnard, Ali Marie, Sisini Sasidharan, Petr Buck, Jessica M. Walker, Julia E. Parker, Thomas E. J. Moxham, Benedikt Daurer, Burkhard Kaulich, Majid Kazemian, Richard M. Shelton, Gabriel Landini, Alexander M. Korsunsky
Summary: This study characterises human dental enamel caries using synchrotron nanoscale imaging techniques combined with scanning electron microscopy. The research reveals the nanoscale variation in chemistry and structure of carious enamel and demonstrates the importance of advanced correlative imaging in investigating the complex structure-composition relationships in nano-materials.
MATERIALS & DESIGN
(2022)
Article
Multidisciplinary Sciences
Guibin Zan, Sheraz Gul, Jin Zhang, Wei Zhao, Sylvia Lewis, David J. Vine, Yijin Liu, Piero Pianetta, Wenbing Yun
Summary: The study developed a TLI system with MAAST source, offering high-resolution and tri-contrast X-ray imaging for biomedical applications. Tomography of Drum fish tooth revealed valuable complementary structural information using this method.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Computer Science, Interdisciplinary Applications
Manuel Viermetz, Nikolai Gustschin, Clemens Schmid, Jakob Haeusele, Peter B. Noel, Roland Proksa, Stefan Loscher, Thomas Koehler, Franz Pfeiffer
Summary: Computed tomography (CT) is an important clinical diagnostics method, but its current limit to X-rays' attenuation contrast only can be expanded with dark-field imaging. Dark-field imaging offers access to more tissue properties, such as micro-structural texture or porosity. However, up-scaling this method to clinical scale is complex due to design constraints such as limited manufacturing technology and minimal modifications to the CT gantry. In this study, the advantages of an inverse interferometer and a triangular grating profile are discussed, making a compact and sensitive interferometer implementation feasible. The evaluation of the triangular grating profile reveals a deviation in the interference pattern compared to standard grating profiles, which must be taken into consideration in subsequent data processing.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2023)
Article
Computer Science, Interdisciplinary Applications
Manuel Viermetz, Nikolai Gustschin, Clemens Schmid, Jakob Haeusele, Bernhard Gleich, Bernhard Renger, Thomas Koehler, Franz Pfeiffer
Summary: X-ray computed tomography (CT) is an important imaging technique in clinical diagnostics. Dark-field CT, which provides additional microstructural information, has shown potential clinical value. In this paper, the performance of a prototype dark-field CT system is discussed, including the evaluation of the interferometer components and challenges related to integration into the CT gantry. The impact of the X-ray source and vibrations on the system are analyzed, and a beam hardening correction is introduced to enable quantitative dark-field imaging. The resolution and patient dose are also analyzed, and initial patient studies using the presented dark-field CT system are suggested.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2023)
Article
Instruments & Instrumentation
Masashi Kageyama, Kenichi Okajima, Minoru Maesawa, Masahiro Nonoguchi, Manabu Nonoguchi, Masaru Kuribayashi, Yukihiro Hara, Atsushi Momose
Summary: The study developed and tested a laboratory assembled X-ray phase CT system with high spatial and density resolution, which successfully distinguishes different materials. The system can also switch to another mode with a wider field of view.
JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Chen Huang, Judy S. Kim, Angus I. Kirkland
Summary: There is a need for characterisation techniques that provide detailed information about structure-function relationships in biology. In this review, the potential of cryogenic electron ptychography as an alternative method for characterising biological systems under low-fluence conditions is explored, discussing its progress, limitations, and potential areas for future development in both single particle analysis and applications to heterogeneous large objects.
CURRENT OPINION IN STRUCTURAL BIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Sebastian Weber, Ana Diaz, Mirko Holler, Andreas Schropp, Mikhail Lyubomirskiy, Ken L. Abel, Maik Kahnt, Arno Jeromin, Satishkumar Kulkarni, Thomas F. Keller, Roger Glaser, Thomas L. Sheppard
Summary: This study utilizes in situ 2D hard X-ray ptychography (XRP) and 3D ptychographic X-ray computed tomography (PXCT) to investigate the synthesis process of hierarchically porous materials. The XRP allows for the monitoring of textural changes, while PXCT provides quantitative information on pore structures. The findings are corroborated with traditional pore characterization methods, leading to a better understanding of the synthesis pathways of porous materials.
Article
Optics
G. Perez-Callejo, V. Bouffetier, L. Ceurvorst, T. Goudal, S. R. Klein, D. Svyatskiy, M. Holec, P. Perez-Martin, K. Falk, A. Casner, T. E. Weber, G. Kagan, M. P. Valdivia
Summary: Diagnosing the evolution of laser-generated high energy density (HED) systems is fundamental to understand the behavior of matter under extreme conditions. Talbot-Lau interferometry was used to probe the ablation front of a laser-irradiated foil, and attenuation and phase-shift images were successfully obtained for electron densities above 10^22 cm^-3. These results demonstrate the capabilities of Talbot-Lau X-ray diagnostic methods to diagnose HED laser-generated plasmas through high-resolution imaging.
HIGH POWER LASER SCIENCE AND ENGINEERING
(2023)
Article
Instruments & Instrumentation
Max Langer, Yuhe Zhang, Diogo Figueirinhas, Jean-Baptiste Forien, Kannara Mom, Claire Mouton, Rajmund Mokso, Pablo Villanueva-Perez
Summary: PyPhase is a free and open-source package for propagation-based near-field phase reconstructions, distributed under the CeCILL license. It implements popular phase-retrieval algorithms in a highly modular framework, supporting deployment on large-scale computing facilities. Its integration and deployment on different computing infrastructures are straightforward, as demonstrated by its capabilities when applied to data acquired at the synchrotron source MAX IV in Lund, Sweden.
JOURNAL OF SYNCHROTRON RADIATION
(2021)
Review
Engineering, Biomedical
Lina Felsner, Philipp Roser, Andreas Maier, Christian Riess
Summary: This study compared different methods to correct artifacts in tomographic reconstructions, finding that the iterative reconstruction algorithm, known operator network, and U-net all reduced specific artifacts but exhibited different noise behaviors.
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2021)
Article
Chemistry, Multidisciplinary
Zhuoya Dong, Enci Zhang, Yilan Jiang, Alvaro Mayoral, Qing Zhang, Yanhang Ma, Huaidong Jiang
Summary: In this study, electron ptychography was used to directly observe the local structures of two zeolites, Na-LTA and ZSM-5. The framework atoms and extra-framework cations were successfully imaged. This approach provides a new way to locally image zeolite structures and is important for further studying and tuning zeolite active sites at the atomic level.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Nanoscience & Nanotechnology
Hao Yuan, Hui Yuan, Travis Casagrande, David Shapiro, Young-Sang Yu, Bjoern Enders, Jonathan R. Lee, Anthony van Buuren, Monika M. Biener, Stuart A. Gammon, Theodore F. Baumann, Adam P. Hitchcock
Summary: The 3D chemical structure and distribution of ZnO coated nanoporous Al2O3 aerogels were studied using multienergy scanning transmission X-ray microscopy and ptychographic imaging. Results show nonuniform coverage of ZnO on the Al2O3 aerogel framework, with different ZnO loadings and sample preparation methods affecting the distribution. FIB methods were found to create sample artifacts, with Xe plasma FIB causing less distortion than Ga ion FIB.
ACS APPLIED NANO MATERIALS
(2021)
Article
Physics, Applied
Alessandra Patera, Carolina Arboleda, Veronica Ferrero, Elisa Fiorina, Konstantins Jefimovs, Alessandro Lo Giudice, Felix Mas Milian, Paolo Mereu, Stefania Pallotta, Luciano Ramello, Alessandro Re, Lorenzo Visca, Piergiorgio Cerello
Summary: The 4D GRAPH-X project aims to develop a prototype of an x-ray grating-based phase-contrast imaging scanner in a laboratory setting, optimized for analyzing moving objects and potential biomedical applications. Wave field simulations are used to optimize the setup specifications and construct a high-resolution and high-sensitivity imaging system.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Engineering, Biomedical
Qisi Lin, Zhao Wu, Guibin Zan, Meng Huang, Zheng Dang, Lijiao Tian, Yong Guan, Gang Liu, Yalin Lu, Yangchao Tian
Summary: This article successfully extends the FOV of compact XTLI and achieves large field of view imaging at high energy by designing and developing an inverse XTLI coupled with a microarray anode-structured target source. Experimental results demonstrate the potential advantage of phase contrast mode in imaging lung tissue.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)