Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 16, Issue 3-4, Pages 362-369Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2012.04.008
Keywords
-
Categories
Funding
- NIH
- Alfred Sloan Foundation
- David and Lucile Packard Foundations
Ask authors/readers for more resources
Redox enzymes such as FAD-dependent and cytochrome P450 oxygenases play indispensible roles in generating structural complexity during natural product biosynthesis. In the pre-assembly steps, redox enzymes can convert garden variety primary metabolites into unique starter and extender building blocks. In the post-assembly tailoring steps, redox cascades can transform nascent scaffolds into structurally complex final products. In this review, we will discuss several recently characterized redox enzymes in the biosynthesis of polyketides and nonribosomal peptides.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available