Journal
CURRENT MEDICINAL CHEMISTRY
Volume 21, Issue 36, Pages 4169-4185Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867321666140716100056
Keywords
Alzheimer's disease; AD imaging; AD therapy; nanocarriers; theranostic nanomedicine
Ask authors/readers for more resources
Up to date, Alzheimer's Disease (AD) is considered as an urgency for public health, since it represents one of the most dramatic causes of death in adults. The drugs currently used for AD are only symptomatic, thus not curing the pathology, but only trying to slow or delay the progression of the pathology. Moreover, there is a total lack of early identification, with only probable'' or possible'' diagnosis of AD patients. With this review, we aimed to individuate and to highlight the most promising approaches for AD therapy and diagnosis. In this view, at the cutting-edge of innovation, nanocarriers as polymeric nanoparticles, liposomes, nanoassembly and dendrimers, have been studied and investigated in order to ameliorate the detection (in vitro and in vivo) and/or the therapeutic options in AD. In this review, the most outstanding nanomedicine-driven approaches in AD imaging/detection and treatments are summarized in order to help in individuating values and criticisms. Moreover, an overview of one of the most innovative strategies in AD management, namely theranostic nanomedicine, is reported and commented.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available