Pharmacological treatment of chronic pain – the need for CHANGE

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study

(2009) Martin Hale et al.   CURRENT MEDICAL RESEARCH AND OPINION

New Pain Guideline for Older Patients

(2009) Bridget M. Kuehn   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Opioid Prescribing Practices in Chronic Pain Management: Guidelines Do Not Sufficiently Influence Clinical Practice

(2009) Timothy W. Victor et al.   JOURNAL OF PAIN

Opioid Metabolism and Effects of Cytochrome P450

(2009) Gregory L. Holmquist   PAIN MEDICINE

Nausea and Vomiting Side Effects with Opioid Analgesics during Treatment of Chronic Pain: Mechanisms, Implications, and Management Options

(2009) Frank Porreca et al.   PAIN MEDICINE

Management of cancer pain: ESMO Clinical Recommendations

(2008) L. Jost et al.   ANNALS OF ONCOLOGY

Efficacy of Opioids for Chronic Pain

(2008) Jane C. Ballantyne et al.   CLINICAL JOURNAL OF PAIN

Management of Expected and Unexpected Opioid-related Side Effects

(2008) Juan-Diego Harris   CLINICAL JOURNAL OF PAIN

Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain

(2008) K. Simpson et al.   CURRENT MEDICAL RESEARCH AND OPINION

Role of active metabolites in the use of opioids

(2008) Janet K. Coller et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Prolonged-release oxycodone enhances the effects of existing gabapentin therapy in painful diabetic neuropathy patients

(2008) Magdi Hanna et al.   EUROPEAN JOURNAL OF PAIN

Epidemiology of chronic pain in Denmark: An update

(2008) Per Sjøgren et al.   EUROPEAN JOURNAL OF PAIN

Costs of back pain in Germany

(2008) Christina M. Wenig et al.   EUROPEAN JOURNAL OF PAIN

A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation

(2008) Winfried Meissner et al.   EUROPEAN JOURNAL OF PAIN

(224) Tapentadol immediate release compared with oxycodone immediate release for the relief of moderate-to-severe pain in patients with end stage joint disease

(2008) M. Afilalo et al.   JOURNAL OF PAIN

Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness

(2008) Jay Thomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain

(2008) Lynn Webster et al.   PAIN

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE

Opioids and the Management of Chronic Severe Pain in the Elderly: Consensus Statement of an International Expert Panel with Focus on the Six Clinically Most Often Used World Health Organization step III Opioids (Buprenorphine, Fentanyl, Hydromorphone, Methadone, Morphine, Oxycodone)

(2008) Joseph Pergolizzi et al.   Pain Practice