Article
Medicine, General & Internal
Dilara Bayram, Volkan Aydin, Ayse Gelal, Mesil Aksoy, Ahmet Akici
Summary: The study in primary care in Turkey showed a modest upward trend in the utilization of generic drugs, but their share was lower than expected. Generic drug prescriptions were higher in women than in men, and decreased with age. Generic drugs were mainly prescribed for acute conditions, especially infectious diseases.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Oncology
Bryan S. Walsh, Aaron S. Kesselheim, Ameet Sarpatwari, Benjamin N. Rome
Summary: This study assessed the use of generic versions of imatinib for indications included and excluded from the skinny labels. The results showed that within 3 years after generics entered the market, more than 90% of initiators in both groups (CML and GIST) used generic imatinib.
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Inna Thalmann, David Preiss, Iryna Schlackow, Alastair Gray, Borislava Mihaylova
Summary: This study aimed to determine the extent of suboptimal statin use for secondary prevention of atherosclerotic cardiovascular disease (ASCVD) and identify patient groups at risk of inadequate treatment. The study found that statin use remains insufficient for ASCVD patients, particularly among women, older patients, and those hospitalized for ischemic stroke and peripheral arterial disease.
Article
Health Care Sciences & Services
David Youens, Jenny Doust, Suzanne Robinson, Rachael Moorin
Summary: The study shows an association between continuity and regularity of primary care with statin medication use among individuals at risk of cardiovascular disease. Patients with higher levels of continuity and regularity are more likely to initiate statin medication and adhere to treatment regimens.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Lina Zhang, Weihao Wang, Fuli Man, Qi Pan, Lixin Guo
Summary: Long-term statin adherence among T2DM patients after PCI in Beijing is still low, and improving statin adherence can reduce the rate of all-cause readmission, revascularization, and cerebrovascular disease.
CARDIOVASCULAR DRUGS AND THERAPY
(2023)
Article
Economics
Benjamin N. Rome, Ameet Sarpatwari, Aaron S. Kesselheim
Summary: Substituting brand-name drugs with cheaper, equally effective generic alternatives is an important strategy to promote adherence and control prescription drug spending. This study found that states with laws requiring patient consent or notification for pharmacist substitution of generics had lower use of generics, while mandating substitution and protecting pharmacists from liability did not appear to have significant effects.
Article
Clinical Neurology
Bruno Kusznir Vitturi, Rubens Jose Gagliardi
Summary: This study aimed to evaluate the risk factors and effects of poor adherence or statin interruption on the clinical outcomes of ischemic stroke patients. The results showed that patients with poor adherence were significantly associated with worse functional outcomes and higher incidence of stroke recurrence, while significant functional recovery was only seen in patients with satisfactory adherence.
NEUROLOGICAL SCIENCES
(2021)
Article
Pediatrics
Edward L. Schor, David Bergman
Summary: Well-child care is a universal service for young children that requires personalized care based on individual and family needs. Reconsidering the traditional schedule of preventive care visits and providing comprehensive care over a series of visits will lead to more efficient and effective preventive care. This model of care will require changes in training, responsibilities, and reimbursement of healthcare team members, as well as enhanced communication and collaboration among all parties involved, particularly with families.
Article
Oncology
Friederike Braulke, Kathrin Kober, Stefan Rieken, Tonia Brand, Tobias Hartz, Stefanie Seipke, Thomas Asendorf, Jorg Haier
Summary: Interdisciplinary tumor boards (ITBs) are crucial in standard cancer care as they provide guidelines-guided treatment plans tailored to the patient's needs in a multi-professional team. However, there is a lack of (inter)national definitions on how to measure the level of implementation. This study presents the results of 4 years of ITB adherence analyses in a bicentric German Comprehensive Cancer Center (CCC).
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Pharmacology & Pharmacy
Przemyslaw Kardas, Aneta Lichwierowicz, Filip Urbanski, Beata Szadkowska-Opasiak, Ewa Karasiewicz, Pawel Lewek, Dominika Krupa, Marcin Czech
Summary: The implementation of generic substitution in Poland has shown suboptimal results, indicating a need for further actions to maximize benefits. It could potentially lead to significant savings for both patients and national payers, as well as improve patient adherence.
Article
Cardiac & Cardiovascular Systems
Francois Schiele, Nadia Quignot, Artak Khachatryan, Gaelle Gusto, Guillermo Villa, Doreen Kahangire, Jean-Vannak Chauny, Lea Ricci, Gaelle Desamericq
Summary: The study found that high-intensity LLT prescriptions were limited and adherence to LLT was low among patients with a history of myocardial infarction. Higher treatment intensity, adherence, and adherence-adjusted intensity were all associated with a significantly lower risk of major adverse cardiovascular events.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Giorgio Bosso, Mariarosaria De Luca, Giovanni Alma, Vincenzo Carbone, Ferdinando Ferrara, Biagio Fimiani, Franco Guarnaccia, Alessandro Iandolo, Sabato Murolo, Maurizio Olivares, Emanuele Romeo, Giosue Santoro, Antonio Valvano, Giovanni Zito, Ugo Oliviero
Summary: This study evaluated the adherence to guidelines-oriented dyslipidaemia's treatment in an outpatient population and found that optimizing therapies improved LDL-c levels in patients of different cardiovascular risks. The results showed a significant reduction in LDL-c in all risk categories at the end of the study, with an increase in the percentage of patients reaching lipid targets. It suggests carefully implementing measures to encourage outpatients and their cardiologists to achieve the targeted lipid profile according to cardiovascular risk.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jingwei Gao, Tomotsugu Seki, Koji Kawakami
Summary: In Japanese population, patients who initiated generic statins showed higher adherence and persistence compared to brand-name statins, with no significant differences in clinical outcomes observed between the two groups.
JOURNAL OF CARDIOLOGY
(2021)
Review
Health Care Sciences & Services
Rajeev Shrestha, Sunil Shrestha, Binaya Sapkota, Santosh Thapa, Mukhtar Ansari, Asmita Priyadarshini Khatiwada, Rohullah Roien, Akihiko Ozaki
Summary: This article discusses the current scenario of generic medicines, generic prescribing, and the obstacles to promoting their usage in Nepal. It highlights the lack of facilities, understanding, and regulation as major challenges, and emphasizes the need for rational pharmaceutical promotion and awareness among healthcare providers and the public.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2022)
Article
Pharmacology & Pharmacy
Zhan-Miao Yi, Sarah Willis, Yuan Zhang, Na Liu, Qi-Yu Tang, Suo-Di Zhai
Summary: This study aimed to examine the impact of a collaborative pharmaceutical care service (CPCS) on medication safety and patient-reported outcomes for Parkinson's disease (PD) patients. Comparisons were made between PD outpatients receiving the CPCS and those receiving standard of care, showing differences in medication management. The CPCS was found to effectively resolve drug-related problems and improve medication regimens, medication adherence, and quality of life through patient education and dosage adjustments.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Hematology
Randall Curtis, Judith Baker, Brenda Riske, Megan Ullman, Xiaoli Niu, Kristi Norton, Mimi Lou, Michael B. Nichol
AMERICAN JOURNAL OF HEMATOLOGY
(2015)
Article
Economics
Zheng-Yi Zhou, Marion A. Koerper, Kathleen A. Johnson, Brenda Riske, Judith R. Baker, Megan Ullman, Randall G. Curtis, Jiat-Ling Poon, Mimi Lou, Michael B. Nichol
JOURNAL OF MEDICAL ECONOMICS
(2015)
Article
Health Care Sciences & Services
Steven W. Blume, Karen Yeomans, Felicia Allen-Ramey, Nancy Smith, Harold Kim, Richard F. Lockey, Michael B. Nichol
JOURNAL OF MANAGED CARE & SPECIALTY PHARMACY
(2015)
Article
Medicine, General & Internal
Tara K. Knight, Aniket Kawatkar, Paul Hodgkins, Robert Moss, Li-Hao Chu, Vanja Sikirica, M. Haim Erder, Michael B. Nichol
CURRENT MEDICAL RESEARCH AND OPINION
(2014)
Article
Hematology
X. Niu, J. L. Poon, B. Riske, Z. Y. Zhou, M. Ullman, M. Lou, J. Baker, M. Koerper, R. Curtis, M. B. Nichol
Article
Economics
Aniket A. Kawatkar, Joel W. Hay, William Stohl, Michael B. Nichol
Article
Health Care Sciences & Services
Jiat-Ling Poon, Jason N. Doctor, Michael B. Nichol
JOURNAL OF GENERAL INTERNAL MEDICINE
(2014)
Article
Economics
Aniket A. Kawatkar, Tara K. Knight, Robert A. Moss, Vanja Sikirica, Li-Hao Chu, Paul Hodgkins, M. Haim Erder, Michael B. Nichol
Article
Hematology
Chatree Chai-Adisaksopha, Declan Noone, Randall Curtis, Neil Frick, Michael B. Nichol, Federico Germini, Brian O'Mahony, David Page, Jeffrey S. Stonebraker, Mark W. Skinner, Alfonso Iorio
Summary: This study aimed to evaluate the health status of people living with mild or moderate hemophilia and found that hemophilia has a significant impact on patients' quality of life, especially in terms of bleeding-related issues. The research suggests that future studies are needed to identify optimal care management for patients with mild and moderate hemophilia.
Article
Hematology
Randall Curtis, Marilyn Manco-Johnson, Barbara A. Konkle, Roshni Kulkarni, Joanne Wu, Judith R. Baker, Megan Ullman, Jr. Duc Quang Tran, Michael B. Nichol
Summary: Older hemophilia patients in the sample are over-represented by individuals with mild/moderate disease. Compared to the younger group, they have fewer healthcare visits and physical therapy, but experience more joint problems and lower quality of life.
JOURNAL OF BLOOD MEDICINE
(2022)
Article
Hematology
Randall Curtis, Jonathan C. Roberts, Nicole Crook, Marquita Decker-Palmer, Rahul Khainar, Judith R. Baker, Megan Ullman, Marion A. Koerper, Joanne Wu, Michael B. Nichol
Summary: This study aimed to describe trends in clinician prescribing practices for the management of haemophilia in the US. Surveys were administered to members of the Hemostasis and Thrombosis Research Society, and the results showed changing trends in prescribing practices among haemophilia specialists in the US over the past 22 years, with an increased preference for factor concentrates and high-dose factor use, and an expectation for the value of gene therapy for some haemophilia patients.
Article
Gerontology
Adria E. Navarro, Julia Wysong, Marguerite DeLiema, Elizabeth L. Schwartz, Michael B. Nichol, Kathleen H. Wilber
Meeting Abstract
Gerontology
B. Kuang, Z. D. Gassoumis, K. H. Wilber, M. B. Nichol
Article
Health Care Sciences & Services
JaeJin An, Michael B. Nichol
Meeting Abstract
Hematology
X. Niu, J. Poon, M. Lou, R. Kulkarni, J. R. Baker, M. B. Nichol, R. G. Curtis, M. Koerper, B. Riske, M. M. Ullman