Journal
CURRENT HYPERTENSION REPORTS
Volume 15, Issue 3, Pages 260-267Publisher
SPRINGER
DOI: 10.1007/s11906-013-0333-8
Keywords
Hypertension; Blood pressure; BP; Dietary supplements; Nutraceuticals; Clinical evidence; Review
Categories
Funding
- Menarini International
- Servier International
- Recordati International
- Boehringer-Ingelheim
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Beyond the well-known effects on blood pressure (BP) of the DASH and the Mediterranean diets, a large number of studies have investigated the possible a BP-lowering effect from different dietary supplements and nutraceuticals, mostly antioxidant agents with a high tolerability and safety profile. In particular, a relatively large body of evidence support the use of potassium, L-arginine, vitamin C, cocoa flavonoids, coenzyme Q10, controlled-release melatonin, and aged garlic extract. However there is a need for data about the long-term safety of a large part of these products. Moreover, further clinical research is advisable to identify between the available active nutraceuticals and those with the best cost-effectiveness and risk-benefit ratio for widespread use in a general population with low added cardiovascular risk related to uncomplicated hypertension.
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