4.0 Article

The Dynamic Face of HIV-1 Subtypes Among Men who have Sex with Men in Beijing, China

Journal

CURRENT HIV RESEARCH
Volume 9, Issue 2, Pages 136-139

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157016211795569096

Keywords

HIV-1; MSM; molecular epidemiology; vaccine; subtype; recombinant

Funding

  1. Chinese National Grand Program on Key Infectious Disease Control and Prevention [2008ZX10001-015, 2008ZX10001-002]
  2. Program for Outstanding Scientist in Shanghai [10XD1403500]
  3. Leading Scientist in Medical Science (Shanghai Health Science and Education) [2010-058]

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The rapid increase of HIV-1 prevalence among Chinese men who have sex with men (MSM) provides an impetus for the acquisition of molecular epidemiologic information from this population. We conducted four serial cross-sectional surveys during the years 2005-2009 and observed that the composition of HIV-1 subtypes was dynamically changing from clade B to CRF01_AE from years 2005-2009. HIV-1 infection in this population includes the persistent circulation of multiple HIV-1 subtypes and complex new recombinants.

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