The expanding syndrome of amyotrophic lateral sclerosis: a clinical and molecular odyssey

Early dipeptide repeat pathology in a frontotemporal dementia kindred with C9ORF72 mutation and intellectual disability

(2014) Malcolm Proudfoot et al.   ACTA NEUROPATHOLOGICA

Dissection of genetic factors associated with amyotrophic lateral sclerosis

(2014) Claire S. Leblond et al.   EXPERIMENTAL NEUROLOGY

Amyotrophic lateral sclerosis: a long preclinical period?

(2014) A. Eisen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clogging information flow in ALS

(2014) J. W. Paul et al.   SCIENCE

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins

(2014) S. Mizielinska et al.   SCIENCE

Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells

(2014) I. Kwon et al.   SCIENCE

Exercise, APOE genotype, and the evolution of the human lifespan

(2014) David A. Raichlen et al.   TRENDS IN NEUROSCIENCES

Is animal research sufficiently evidence based to be a cornerstone of biomedical research?

(2014) P. Pound et al.   BMJ-British Medical Journal

Dietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis

(2014) Kathryn C. Fitzgerald et al.   JAMA Neurology

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

(2013) Johannes Brettschneider et al.   ANNALS OF NEUROLOGY

Amyotrophic lateral sclerosis: cell vulnerability or system vulnerability?

(2013) Kevin Talbot   JOURNAL OF ANATOMY

Fasciculation potentials and earliest changes in motor unit physiology in ALS

(2013) M. de Carvalho et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Lifetime physical activity and the risk of amyotrophic lateral sclerosis

(2013) M. H. B. Huisman et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Tools and talk: An evolutionary perspective on the functional deficits associated with amyotrophic lateral sclerosis

(2013) Andrew Eisen et al.   MUSCLE & NERVE

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Cognitive changes predict functional decline in ALS: A population-based longitudinal study

(2013) M. Elamin et al.   NEUROLOGY

Enlarging the clinical spectrum associated with C9orf 72 repeat expansions: Findings in an Italian cohort of patients with Parkinsonian syndromes and relevance for genetic counselling

(2013) Paola Origone et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Does variation in neurodegenerative disease susceptibility and phenotype reflect cerebral differences at the network level?

(2013) Andrew Eisen et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Mechanisms, models and biomarkers in amyotrophic lateral sclerosis

(2013) Martin R. Turner et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Does interneuronal dysfunction contribute to neurodegeneration in amyotrophic lateral sclerosis?

(2012) Martin R. Turner et al.   Amyotrophic Lateral Sclerosis

Young-onset amyotrophic lateral sclerosis: historical and other observations

(2012) M. R. Turner et al.   BRAIN

Reduced cancer incidence in Huntington's disease: record linkage study clue to an evolutionary trade-off?

(2012) MR Turner et al.   CLINICAL GENETICS

Phenotype difference between ALS patients with expanded repeats inC9ORF72and patients with mutations in other ALS-related genes

(2012) Stéphanie Millecamps et al.   JOURNAL OF MEDICAL GENETICS

How does ALS spread between neurones in the CNS?

(2012) Michael Swash   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study

(2012) Susan Byrne et al.   LANCET NEUROLOGY

Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study

(2012) Elisa Majounie et al.   LANCET NEUROLOGY

Presymptomatic studies in ALS: Rationale, challenges, and approach

(2012) M. Benatar et al.   NEUROLOGY

Predicting Regional Neurodegeneration from the Healthy Brain Functional Connectome

(2012) Juan Zhou et al.   NEURON

A Unifying Role for Prions in Neurodegenerative Diseases

(2012) S. B. Prusiner   SCIENCE

Isolated bulbar phenotype of amyotrophic lateral sclerosis

(2011) James R. Burrell et al.   Amyotrophic Lateral Sclerosis

What wires together dies together: Verbs, actions and neurodegeneration in motor neuron disease

(2011) Thomas H. Bak et al.   CORTEX

Modelling the Effects of Penetrance and Family Size on Rates of Sporadic and Familial Disease

(2011) Ammar Al-Chalabi et al.   HUMAN HEREDITY

Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALS

(2011) C. R. V. Blain et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

(2011) Julie Phukan et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The split hand syndrome in amyotrophic lateral sclerosis

(2011) Andrew Eisen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Phenotypic heterogeneity of amyotrophic lateral sclerosis: a population based study

(2011) A. Chio et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

(2011) Thomas Philips et al.   LANCET NEUROLOGY

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

(2011) Peter M. Andersen et al.   Nature Reviews Neurology

Executive dysfunction is a negative prognostic indicator in patients with ALS without dementia

(2011) M. Elamin et al.   NEUROLOGY

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

(2011) Christian Münch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cognitive impairment in motor neuron disease

(2010) R. Gallassi et al.   ACTA NEUROLOGICA SCANDINAVICA

Amyotrophic lateral sclerosis, physical exercise, trauma and sports: Results of a population-based pilot case-control study

(2010) Ettore Beghi et al.   Amyotrophic Lateral Sclerosis

Lockhart Clarke's contribution to the description of amyotrophic lateral sclerosis

(2010) M. R. Turner et al.   BRAIN

Progression in ALS is not linear but is curvilinear

(2010) Paul H. Gordon et al.   JOURNAL OF NEUROLOGY

Concordance between site of onset and limb dominance in amyotrophic lateral sclerosis

(2010) M. R. Turner et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations

(2010) D. Baumer et al.   NEUROLOGY

Head and other physical trauma requiring hospitalisation is not a significant risk factor in the development of ALS

(2009) Martin R. Turner et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

ALS motor phenotype heterogeneity, focality, and spread: Deconstructing motor neuron degeneration

(2009) J. M. Ravits et al.   NEUROLOGY

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis

(2008) Steve Vucic et al.   BRAIN