Review
Clinical Neurology
Lele Huang, Dan Zhang, Jianling Ji, Yujie Wang, Ruijun Zhang
Summary: The central retina thickness, the combination of ganglion cell layer and inner plexiform layer thickness, and nerve fiber layer thickness were significantly decreased in patients with Parkinson's disease (PD). However, there was no significant difference in the thickness of the inner nuclear layer, outer plexiform layer, and outer nuclear layer between the eyes of PD patients and controls. Subgroup analysis and meta-regression results were consistent with the main findings.
JOURNAL OF NEUROLOGY
(2021)
Article
Optics
Zhenhe Ma, Ning Ding, Zhen Li, Keliang Zhu, Ang Li, Zhanhong Lin, Yi Wang, Yuqian Zhao, Yao Yu, Jingmin Luan, Xin Zhu, Jian Liu
Summary: This article introduces a method to extract the photoacoustic (PA) signal from the contrast reduction in the interference spectrum obtained from spectral domain optical coherence tomography (SDOCT). The method utilizes the specular reflection on the water surface to achieve all-optical detection in a non-contact manner. By analyzing the phase changes in the interference spectrum induced by water surface vibration, the method enables quantification of the interference contrast reduction for PA imaging.
Article
Clinical Neurology
Yifan Zhang, Li Yang, Yuzhu Gao, Dan Zhang, Yunhan Tao, Hanyue Xu, Yi Chen, Yanming Xu, Ming Zhang
Summary: This study found that Parkinson's disease patients have decreased contrast sensitivity, thinning of the outer retinal layer and choroid, decreased choriocapillaris flow density, CVI, and CVV. There is a weak correlation between outer retina thickness and contrast sensitivity.
ALZHEIMERS RESEARCH & THERAPY
(2022)
Article
Optics
Yuye Ling, Zhenxing Dong, Xueshen Li, Yu Gan, Yikai Su
Summary: With the advancement of light source technology, the A-line imaging rate of SS-OCT has significantly increased in the past three decades. However, the bandwidths of data acquisition, transfer, and storage have become major limitations in modern SS-OCT system design. To address this, a novel design paradigm is proposed where the sub-sampling pattern for interferogram acquisition is jointly optimized with the reconstruction algorithm. This method achieves high data compression ratios without impairing image quality, making it a potential solution for the data issue in SS-OCT.
Article
Optics
Tanbin Shao, Kecheng Yang, Min Xia, Wenping Guo
Summary: In this study, an enhanced dispersion-encoded full-range spectral interferometry technique is proposed and validated for improving measurement accuracy in samples with significant depth, inclination, and roughness. By removing the direct current and preserving data with good phase continuity, the accuracy of phase compensation is improved. The proposed technique extends the depth measurement range and achieves high axial measurement precision.
Review
Medicine, General & Internal
Yong Woo Lee, Myung-Nam Lim, Jae Yeon Lee, Yung-Ju Yoo
Summary: This meta-analysis revealed significant differences in retinal thickness between patients with Parkinson disease and healthy controls, suggesting the potential of spectral-domain optical coherence tomography (SD-OCT) in detecting biomarkers for PD diagnosis and providing valuable guidance for clinicians.
Article
Medicine, General & Internal
Lisa Toto, Maria Ludovica Ruggeri, Federica Evangelista, Chiara Trivigno, Rossella D'Aloisio, Chiara De Nicola, Pasquale Viggiano, Emanuele Doronzo, Marta Di Nicola, Annamaria Porreca, Rodolfo Mastropasqua
Summary: This study investigates the parameters of optical coherence tomography (OCT) and OCT angiography (OCTA) in patients with neovascular age-related macular degeneration (nAMD) and macular neovascularization (MNV) types 1, 2, and 3. The results showed significant differences in CVI, CMT, and ORCCFA between MNV 1 and the other two groups. CVI was significantly different between MNV 1 and healthy controls and between MNV 1 and MNV 2. ORCCFA and CMT were significantly different between MNV 1 and MNV 2. There was no statistically significant difference in subfoveal choroidal thickness (SFCT) among the three groups.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chen Huang, Keren Xie, Yuhan Zhang, Mingchao Li, Songtao Yuan, Qiang Chen
Summary: The proposed fusion method combining SD-OCT and OCTA images is more effective for CNV visualization, providing a satisfying visual effect by integrating complementary information from multimodal images.
Review
Clinical Neurology
Lele Huang, Chen Wang, Wanting Wang, Yujie Wang, Ruijun Zhang
Summary: This study conducted a systematic review and meta-analysis on peripapillar nerve fiber layer (pRNFL) thinning in Parkinson's disease (PD) patients, finding a specific pattern of thinning with the inferotemporal sector being most affected and the nasal quadrant being least affected.
JOURNAL OF NEUROLOGY
(2021)
Review
Clinical Neurology
Wen-Chuan Zhou, Jin-Xin Tao, Jing Li
Summary: This meta-analysis reviewed 36 observational studies and found significant reductions in pRNFL thickness, macular fovea thickness, macular volume, and other OCT measurements in PD patients compared to healthy controls.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Neurosciences
Ane Murueta-Goyena, Maitane Barrenechea, Asier Erramuzpe, Sara Teijeira-Portas, Marta Pengo, Unai Ayala, David Romero-Bascones, Marian Acera, Rocio Del Pino, Juan Carlos Gomez-Esteban, Inigo Gabilondo
Summary: Retinal microvascular alterations were observed in Parkinson's disease patients, affecting both the foveal and parafoveal regions. These alterations were associated with cognitive impairment and could potentially serve as diagnostic biomarkers for PD.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Engineering, Electrical & Electronic
Prabhav Gaur, Andrew Grieco, Yeshaiahu Fainman
Summary: This article presents a method to improve the performance of spectral domain optical coherence tomography by using phase modulators and delay lines as filters, scanning multiple channels and combining them in a digital computer.
IEEE PHOTONICS JOURNAL
(2023)
Article
Chemistry, Analytical
Hong-Yan Zheng, Bo-Liang Chen, Hsiao-Yen Lu, Shih-Hsiang Hsu, Masanori Takabayashi
Summary: A chip-based SD-OCT system utilizes a MZDC structure and an echelle grating for improving signal-to-noise ratios, wavelength response, axial resolution, and sensitivity.
Article
Medicine, General & Internal
Sung Uk Baek, Suk Yun Kang, Soonil Kwon, In Won Park, Wool Suh
Summary: In patients with Parkinson's disease, interocular asymmetry of macular retinal thickness was greater compared to controls, and motor symptoms were asymmetric. Additionally, there was a significant correlation between interocular asymmetry of macular retinal thickness and motor-symptom laterality.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Xinxin Ma, Shuhua Li, Bodi Zheng, Lei Hu, Huijing Liu, Zheng Wang, Zhaoxia Wang, Haibo Chen, Wen Su
Summary: This study investigated retinal structure changes in patients with Parkinson's disease (PD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and controls. The results showed that spectral domain optical coherence tomography (SD-OCT) can be used for differential diagnosis and progression evaluation of parkinsonian syndrome. PD and atypical parkinsonism were found to correlate with specific patterns of retina alterations, and OCT parameters were negatively correlated with disease duration in all three conditions.
Letter
Ophthalmology
Hasan A. Bayhan, Seray Aslan Bayhan, Izzet Can
JOURNAL OF GLAUCOMA
(2017)
Article
Ophthalmology
Ersin Muhafiz, Hasan Ali Bayhan, Sevinc Sahin, Ayse Yesim Gocmen, Seray Aslan Bayhan, Canan Gurdal
Article
Ophthalmology
Bekir Kucuk, Mehmet Hamamci, Seray Aslan Bayhan, Hasan Ali Bayhan, Levent Ertugrul Inan
CURRENT EYE RESEARCH
(2019)
Article
Ophthalmology
Ersin Muhafiz, Seray Aslan Bayhan, Hasan Ali Bayhan, Canan Guerdal
INTERNATIONAL OPHTHALMOLOGY
(2019)
Article
Surgery
Ender Sahin, Murat Serkan Songur, Yunus Kantekin, Hasan Ali Bayhan, Ilknur Haberal Can
JOURNAL OF CRANIOFACIAL SURGERY
(2020)
Article
Ophthalmology
Murat Serkan Songur, Yavuz Selim Intepe, Seray Aslan Bayhan, Hasan Ali Bayhan, Ender Sahin, Bulent Ciftci
Summary: The study evaluated the corneal endothelium in patients with OSAS using specular microscopy, finding significant differences compared to the control group.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Respiratory System
Murat Serkan Songur, Yavuz Selim Intepe, Seray Aslan Bayhan, Hasan Ali Bayhan, Bulent Ciftci
Summary: The study aimed to evaluate the corneal endothelium in patients with COPD, finding that the corneal thickness was significantly reduced and endothelial characteristics differed in COPD patients compared to healthy individuals. The findings suggest that specular microscopy is a valuable tool for monitoring and treating corneal endothelial changes in COPD patients.
CLINICAL RESPIRATORY JOURNAL
(2021)
Article
Clinical Neurology
Mehmet Hamamci, Murat Serkan Songur, Seray Aslan Bayhan, Hasan Ali Bayhan
Summary: This study found that young adult migraine patients with visual aura have lower ocular vascular density values and larger foveal avascular zone, which may be associated with migraine attack frequency and severity.
JOURNAL OF CLINICAL NEUROSCIENCE
(2021)
Meeting Abstract
Surgery
A. Bedirli, C. Buyukkasap, H. Bayhan