Journal
CURRENT DRUG METABOLISM
Volume 10, Issue 5, Pages 482-498Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138920009788898037
Keywords
-
Funding
- National Health & Medical Research Council [2003AA2Z347A]
- National Nature Science Fund from P.R China [30630076]
Ask authors/readers for more resources
Drug transporters expressed on the hepatocyte membrane play an important role in hepatic drug disposition. In the last two decades, systematic research has resulted in a better understanding of the diversity, expression and substrate specificities of drug transporters in the liver. Here we review recent studies on the role of transporters in drug-drug interactions and disease states such as cirrhosis. We conclude the review by considering techniques and model systems used to study hepatic transporters, including the latest technological developments such as multiphoton microscopy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available