Use of Glucagon-Like Peptide-1 Agonists to Improve Islet Graft Performance

Marked Expansion of Exocrine and Endocrine Pancreas With Incretin Therapy in Humans With Increased Exocrine Pancreas Dysplasia and the Potential for Glucagon-Producing Neuroendocrine Tumors

(2013) A. E. Butler et al.   DIABETES

Exendin-4 Increases the Expression of Hypoxia-Inducible Factor-1α in Rat Islets and Preserves the Endocrine Cell Volume of Both Free and Macroencapsulated Islet Grafts

(2012) Xiaohui Jia et al.   CELL TRANSPLANTATION

Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010

(2012) F. B. Barton et al.   DIABETES CARE

Reduction in Carotid Intima-Media Thickness After Pancreatic Islet Transplantation in Patients With Type 1 Diabetes

(2012) K. K. Danielson et al.   DIABETES CARE

No evidence of drug-induced pancreatitis in rats treated with exenatide for 13 weeks

(2012) K. Tatarkiewicz et al.   DIABETES OBESITY & METABOLISM

A meta-analysis of serious adverse events reported with exenatide and liraglutide: Acute pancreatitis and cancer

(2012) Carlos Alves et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2)

(2012) A. D. Barlow et al.   DIABETOLOGIA

Antiapoptotic Actions of Exendin-4 against Hypoxia and Cytokines Are Augmented by CREB

(2012) Kalpana Velmurugan et al.   ENDOCRINOLOGY

Rapamycin Causes Upregulation of Autophagy and Impairs Islets Function Both In Vitro and In Vivo

(2011) M. Tanemura et al.   AMERICAN JOURNAL OF TRANSPLANTATION

In Vivo Imaging of Transplanted Islets with64Cu-DO3A-VS-Cys40-Exendin-4 by Targeting GLP-1 Receptor

(2011) Zhanhong Wu et al.   BIOCONJUGATE CHEMISTRY

Advancing islet transplantation: from engraftment to the immune response

(2011) R. F. Gibly et al.   DIABETOLOGIA

Pancreatitis, Pancreatic, and Thyroid Cancer With Glucagon-Like Peptide-1–Based Therapies

(2011) Michael Elashoff et al.   GASTROENTEROLOGY

Glucagon Like Peptide-1 Receptor Expression in the Human Thyroid Gland

(2011) Belinda Gier et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ex Vivo Imaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist

(2011) Brett M. Connolly et al.   MOLECULAR IMAGING AND BIOLOGY

Improved Outcome of Islet Transplantation in Partially Pancreatectomized Diabetic Mice by Inhibition of Dipeptidyl Peptidase-4 With Sitagliptin

(2011) Young-Seok Kim et al.   PANCREAS

mTOR links incretin signaling to HIF induction in pancreatic beta cells

(2011) S. Van de Velde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accurate measurement of pancreatic islet  -cell mass using a second-generation fluorescent exendin-4 analog

(2011) T. Reiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of glucagon-like peptide-1 gene expression on graft function in mouse islet transplantation

(2011) Hee Young Chae et al.   TRANSPLANT INTERNATIONAL

Comparison of exendin-4 on beta-cell replication in mouse and human islet grafts

(2011) Lei Tian et al.   TRANSPLANT INTERNATIONAL

Stimulating β-Cell Replication and Improving Islet Graft Function by AR231453, A gpr119 Agonist

(2011) J. Gao et al.   TRANSPLANTATION PROCEEDINGS

Reversal of New-Onset Diabetes through Modulating Inflammation and Stimulating β-Cell Replication in Nonobese Diabetic Mice by a Dipeptidyl Peptidase IV Inhibitor

(2010) Lei Tian et al.   ENDOCRINOLOGY

Glucagon-Like Peptide-1 Receptor Agonists Activate Rodent Thyroid C-Cells Causing Calcitonin Release and C-Cell Proliferation

(2010) Lotte Bjerre Knudsen et al.   ENDOCRINOLOGY

Calcineurin Signaling Regulates Human Islet β-Cell Survival

(2010) Scott A. Soleimanpour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GLP-1–Receptor Scanning for Imaging of Human Beta Cells Transplanted in Muscle

(2010) Francois Pattou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Different Effects of FK506, Rapamycin, and Mycophenolate Mofetil on Glucose-Stimulated Insulin Release and Apoptosis in Human Islets

(2009) James D. Johnson et al.   CELL TRANSPLANTATION

Porcine Marginal Mass Islet Autografts Resist Metabolic Failure Over Time and Are Enhanced by Early Treatment with Liraglutide

(2009) Juliet A. Emamaullee et al.   ENDOCRINOLOGY

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

(2009) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture

(2009) Christian Toso et al.   TRANSPLANT INTERNATIONAL

Upregulating CD4+CD25+FOXP3+ Regulatory T Cells in Pancreatic Lymph Nodes in Diabetic NOD Mice by Adjuvant Immunotherapy

(2009) Bole Tian et al.   TRANSPLANTATION

Islet Transplantation for Brittle Type 1 Diabetes: The UIC Protocol

(2008) A. Gangemi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

GLP-1 receptor signaling protects pancreatic beta cells in intraportal islet transplant by inhibiting apoptosis

(2008) Kentaro Toyoda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exendin-4 Treatment Expands Graft β-Cell Mass in Diabetic Mice Transplanted with a Marginal Number of Fresh Islets

(2008) Jyuhn-Huarng Juang et al.   CELL TRANSPLANTATION

Combination Therapy with Glucagon-Like Peptide-1 and Gastrin Induces β-Cell Neogenesis from Pancreatic Duct Cells in Human Islets Transplanted in Immunodeficient Diabetic Mice

(2008) Wilma L. Suarez-Pinzon et al.   CELL TRANSPLANTATION

Inhibition of Dipeptidyl Peptidase IV With Sitagliptin (MK0431) Prolongs Islet Graft Survival in Streptozotocin-Induced Diabetic Mice

(2008) S.-J. Kim et al.   DIABETES

Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice

(2008) W. L. Suarez-Pinzon et al.   DIABETES

Dipeptidyl Peptidase IV Inhibition With MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-Cell Modulation

(2008) S.-J. Kim et al.   DIABETES

Resolving the Conundrum of Islet Transplantation by Linking Metabolic Dysregulation, Inflammation, and Immune Regulation

(2008) Xiaolun Huang et al.   ENDOCRINE REVIEWS

Liraglutide, a Long-Acting Human Glucagon-Like Peptide 1 Analog, Improves Glucose Homeostasis in Marginal Mass Islet Transplantation in Mice

(2008) S. Merani et al.   ENDOCRINOLOGY

Effect of Glucagon-Like Peptide-1 on β- and α-Cell Function in Isolated Islet and Whole Pancreas Transplant Recipients

(2008) Michael R. Rickels et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Exenatide and Rare Adverse Events

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

2008 Update From the Collaborative Islet Transplant Registry

(2008) Rodolfo Alejandro et al.   TRANSPLANTATION

Improved Long-Term Health-Related Quality of Life After Islet Transplantation

(2008) Thipaporn Tharavanij et al.   TRANSPLANTATION

Long-Term Insulin Independence and Improvement in Insulin Secretion After Supplemental Islet Infusion Under Exenatide and Etanercept

(2008) Raquel N. Faradji et al.   TRANSPLANTATION