Transplantation of Xenogeneic Islets: Are We There Yet?

Novel Sphingosine-1-Phosphate Receptor Modulator KRP203 Combined With Locally Delivered Regulatory T Cells Induces Permanent Acceptance of Pancreatic Islet Allografts

(2013) Mithun Khattar et al.   TRANSPLANTATION

Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model

(2013) Jamie L. Brady et al.   XENOTRANSPLANTATION

Belatacept and Sirolimus Prolong Nonhuman Primate Islet Allograft Survival: Adverse Consequences of Concomitant Alefacept Therapy

(2012) M. C. Lowe et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A Novel Monoclonal Antibody to CD40 Prolongs Islet Allograft Survival

(2012) M. Lowe et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Islet Cell Transplantation in Type 1 Diabetes: An Analysis of Efficacy Outcomes and Considerations for Trial Designs

(2012) J. L. Tiwari et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Innate cellular immunity and xenotransplantation

(2012) Hui Wang et al.   Current Opinion in Organ Transplantation

Mesenchymal stromal cells as a means of controlling pathological T-cell responses in allogeneic islet transplantation

(2012) James L. Reading et al.   Current Opinion in Organ Transplantation

Xenografted Islet Cell Clusters From INSLEA29Y Transgenic Pigs Rescue Diabetes and Prevent Immune Rejection in Humanized Mice

(2012) N. Klymiuk et al.   DIABETES

Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression

(2012) Kate L. Graham et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transgenic swine: Expression of human CD39 protects against myocardial injury

(2012) Debra G. Wheeler et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Adoptive Infusion of Tolerogenic Dendritic Cells Prolongs the Survival of Pancreatic Islet Allografts: A Systematic Review of 13 Mouse and Rat Studies

(2012) Guixiang Sun et al.   PLoS One

Efficient TALEN-mediated gene knockout in livestock

(2012) D. F. Carlson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of cloned pigs expressing human thrombomodulin in endothelial cells

(2012) Satoko Yazaki et al.   XENOTRANSPLANTATION

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CD40-Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Microparticles in Hemostasis and Thrombosis

(2011) A. Phillip Owens et al.   CIRCULATION RESEARCH

Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment

(2011) Bo Nilsson et al.   Current Opinion in Organ Transplantation

The Importance of Tissue Factor Expression by Porcine NICC in Triggering IBMIR in the Xenograft Setting

(2011) Ming Ji et al.   TRANSPLANTATION

Protection of Porcine Islet Xenografts in Mice Using Sertoli Cells and Monoclonal Antibodies

(2011) Qahir A. Ramji et al.   TRANSPLANTATION

Reduced Progression of Diabetic Microvascular Complications With Islet Cell Transplantation Compared With Intensive Medical Therapy

(2011) David M. Thompson et al.   TRANSPLANTATION

Versatile co-expression of graft-protective proteins using 2A-linked cassettes

(2011) Nella Fisicaro et al.   XENOTRANSPLANTATION

Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes

(2010) Richard M. Bergenstal et al.   NEW ENGLAND JOURNAL OF MEDICINE

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

(2010) E. M. Carrington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Situ Protection Against Islet Allograft Rejection by CTLA4Ig Transduction

(2010) Sarah L. Londrigan et al.   TRANSPLANTATION

Alginate Macroencapsulation of Pig Islets Allows Correction of Streptozotocin-Induced Diabetes in Primates up to 6 Months Without Immunosuppression

(2010) Denis Dufrane et al.   TRANSPLANTATION

Long-Term Controlled Normoglycemia in Diabetic Non-Human Primates After Transplantation with hCD46 Transgenic Porcine Islets

(2009) D. J. van der Windt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Current cellular innate immune hurdles in pig-to-primate xenotransplantation

(2009) Mårten KJ Schneider et al.   Current Opinion in Organ Transplantation

The coagulation barrier in xenotransplantation: incompatibilities and strategies to overcome them

(2009) Peter J Cowan et al.   Current Opinion in Organ Transplantation

Monoclonal antibodies generated by DNA immunization recognize CD2 from a broad range of primates

(2009) Jamie L Brady et al.   IMMUNOLOGY AND CELL BIOLOGY

Complement activation and coagulation in xenotransplantation

(2009) Peter J Cowan et al.   IMMUNOLOGY AND CELL BIOLOGY

Anchoring of Vascular Endothelial Growth Factor to Surface-Immobilized Heparin on Pancreatic Islets: Implications for Stimulating Islet Angiogenesis

(2009) Sanja Cabric et al.   TISSUE ENGINEERING PART A

HLA-E/Human β2-Microglobulin Transgenic Pigs: Protection Against Xenogeneic Human Anti-Pig Natural Killer Cell Cytotoxicity

(2009) Elisabeth H. Weiss et al.   TRANSPLANTATION

Fighting Malignancy in Organ Transplant Recipients

(2009) E.K. Geissler   TRANSPLANTATION PROCEEDINGS

Pig islet xenograft rejection in a mouse model with an established human immune system

(2008) Noriko Tonomura et al.   XENOTRANSPLANTATION