Gene × Environment Interactions in Type 2 Diabetes

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

(2011)   DIABETOLOGIA

Challenges in the Use of Literature-based Meta-Analysis to Examine Gene-Environment Interactions

(2010) L. Palla et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Bioinformatics challenges for genome-wide association studies

(2010) J. H. Moore et al.   BIOINFORMATICS

Genetic Risk Reclassification for Type 2 Diabetes by Age Below or Above 50 Years Using 40 Type 2 Diabetes Risk Single Nucleotide Polymorphisms

(2010) J. M. de Miguel-Yanes et al.   DIABETES CARE

Interactions of Dietary Whole-Grain Intake With Fasting Glucose- and Insulin-Related Genetic Loci in Individuals of European Descent: A meta-analysis of 14 cohort studies

(2010) J. A. Nettleton et al.   DIABETES CARE

Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients

(2010) Alisa K. Manning et al.   GENETIC EPIDEMIOLOGY

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Think zinc: New roles for zinc in the control of insulin secretion

(2010) Guy A. Rutter   Islets

On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study

(2010) Guillaume Paré et al.   PLoS Genetics

Previously Associated Type 2 Diabetes Variants May Interact With Physical Activity to Modify the Risk of Impaired Glucose Regulation and Type 2 Diabetes: A Study of 16,003 Swedish Adults

(2009) E. C. Brito et al.   DIABETES

PPARGC1A sequence variation and cardiovascular risk-factor levels: a study of the main genetic effects and gene × environment interactions in children from the European Youth Heart Study

(2009) E. C. Brito et al.   DIABETOLOGIA

Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study

(2009) S.-M. Ruchat et al.   DIABETOLOGIA

Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden

(2009) Frida Renström et al.   HUMAN MOLECULAR GENETICS

10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study

(2009)   LANCET

SNPs in PPARG Associate with Type 2 Diabetes and Interact with Physical Activity

(2009) TUOMAS O. KILPELÄINEN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Using the Optimal Receiver Operating Characteristic Curve to Design a Predictive Genetic Test, Exemplified with Type 2 Diabetes

(2008) Qing Lu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and Obesity

(2008) Evadnie Rampersaud et al.   ARCHIVES OF INTERNAL MEDICINE

Extension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program

(2008) A. F. Moore et al.   DIABETES

Assessing gene–treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program

(2008) P. W. Franks et al.   DIABETOLOGIA

Increasing the power of identifying gene × gene interactions in genome-wide association studies

(2008) Charles Kooperberg et al.   GENETIC EPIDEMIOLOGY

Thrifty genes for obesity, an attractive but flawed idea and an alternative perspective: the ‘drifty gene’ hypothesis

(2008) J R Speakman   INTERNATIONAL JOURNAL OF OBESITY

The Human Gene Map for Performance and Health-Related Fitness Phenotypes

(2008) MOLLY S. BRAY et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE

Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes

(2008) James B. Meigs et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rationale, Design, and Methodology of the Women's Genome Health Study: A Genome-Wide Association Study of More Than 25 000 Initially Healthy American Women

(2007) P. M Ridker et al.   CLINICAL CHEMISTRY