Journal
CURRENT BIOLOGY
Volume 23, Issue 4, Pages R159-R161Publisher
CELL PRESS
DOI: 10.1016/j.cub.2013.01.020
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By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.
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