Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains

Insulin induces phosphorylation of the AMPA receptor subunit GluR1, reversed by ZIP, and over-expression of Protein Kinase M zeta, reversed by amyloid beta

(2014) Linda Adzovic et al.   JOURNAL OF NEUROCHEMISTRY

Insulin resistance, neuroinflammation, and Alzheimer’s disease

(2014) Dema Najem et al.   REVIEWS IN THE NEUROSCIENCES

Insulin inhibits lipopolysaccharide-induced nitric oxide synthase expression in rat primary astrocytes

(2013) Hui Li et al.   BRAIN RESEARCH

Alzheimer’s disease and insulin resistance: translating basic science into clinical applications

(2013) Fernanda G. De Felice   JOURNAL OF CLINICAL INVESTIGATION

Riluzole Partially Rescues Age-Associated, but not LPS-Induced, Loss of Glutamate Transporters and Spatial Memory

(2013) Holly M. Brothers et al.   Journal of Neuroimmune Pharmacology

Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts

(2013) Irving L.M.H. Aye et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Differential effects of duration and age on the consequences of neuroinflammation in the hippocampus

(2013) Isabelle Bardou et al.   NEUROBIOLOGY OF AGING

Assessing Activation States in Microglia

(2012) Carol A. Colton et al.   CNS & Neurological Disorders-Drug Targets

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Risk of Alzheimer’s Disease in Relation to Diabetes: A Population-Based Cohort Study

(2012) Kai-Chen Wang et al.   NEUROEPIDEMIOLOGY

Effect of chronic intracerebroventricular insulin administration in rats on the peripheral glucose metabolism and synaptic plasticity of CA1 hippocampal neurons

(2011) Amer Kamal et al.   BRAIN RESEARCH

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

(2011) Joshua A. Smith et al.   BRAIN RESEARCH BULLETIN

Irs1 Serine 307 Promotes Insulin Sensitivity in Mice

(2010) Kyle D. Copps et al.   Cell Metabolism

Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: Role of PKCζ-mediated p47phox phosphorylation

(2010) Jeremy T. Leverence et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Early-life infection is a vulnerability factor for aging-related glial alterations and cognitive decline

(2010) Staci D. Bilbo   NEUROBIOLOGY OF LEARNING AND MEMORY

Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease

(2010) Piet Eikelenboom et al.   Neurodegenerative Diseases

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

(2010) M. T. Heneka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine

(2009) S. Rosi et al.   BRAIN

An Atypical Protein Kinase C (PKC ) Plays a Critical Role in Lipopolysaccharide-Activated NF- B in Human Peripheral Blood Monocytes and Macrophages

(2009) X. Huang et al.   JOURNAL OF IMMUNOLOGY

Increased levels of proinflammatory cytokines in the aged rat brain attenuate injury-induced cytokine response after excitotoxic damage

(2009) O. Campuzano et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis

(2009) Yannick Marchalant et al.   NEUROBIOLOGY OF DISEASE

Insulin Inhibits LPS-Induced Signaling Pathways in Alveolar Macrophages

(2008) Joilson Martins et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Insulin Suppresses LPS-induced iNOS and COX-2 Expression and NF-κB Activation in Alveolar Macrophages and

(2008) Joilson Martins et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats

(2007) Yannick Marchalant et al.   NEUROBIOLOGY OF AGING