Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition

Microglial Phenotype Is Regulated by Activity of the Transcription Factor, NFAT (Nuclear Factor of Activated T Cells)

(2013) K. Nagamoto-Combs et al.   JOURNAL OF NEUROSCIENCE

Pomegranate Polyphenols and Extract Inhibit Nuclear Factor of Activated T-Cell Activity and Microglial Activation In Vitro and in a Transgenic Mouse Model of Alzheimer Disease

(2013) Lalida Rojanathammanee et al.   JOURNAL OF NUTRITION

NFAT1 Is Highly Expressed in, and Regulates the Invasion of, Glioblastoma Multiforme Cells

(2013) Xinxin Tie et al.   PLoS One

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease

(2012) Gunjan Dhawan et al.   Journal of Neuroinflammation

Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

(2012) E. Hudry et al.   JOURNAL OF NEUROSCIENCE

Distinct Dendritic Spine and Nuclear Phases of Calcineurin Activation after Exposure to Amyloid-  Revealed by a Novel Fluorescence Resonance Energy Transfer Assay

(2012) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

(2012) J. L. Furman et al.   JOURNAL OF NEUROSCIENCE

Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types

(2012) Seth M. Dever et al.   JOURNAL OF NEUROVIROLOGY

Uridine 5'-Diphosphate Induces Chemokine Expression in Microglia and Astrocytes through Activation of the P2Y6 Receptor

(2011) B. Kim et al.   JOURNAL OF IMMUNOLOGY

Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

(2011) Gunjan Dhawan et al.   NEUROBIOLOGY OF AGING

Response of transcription factor NFATc3 to excitotoxic and traumatic brain insults: Identification of a subpopulation of reactive astrocytes

(2010) María C. Serrano-Pérez et al.   GLIA

Rapid Communication: Ca2+ Channel Blockers Attenuate β-Amyloid Peptide Toxicity to Cortical Neurons in Culture

(2010) John H. Weiss et al.   JOURNAL OF NEUROCHEMISTRY

P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways

(2010) Miho Shiratori et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid   Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation

(2010) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

Calcineurin inhibition with FK506 ameliorates dendritic spine density deficits in plaque-bearing Alzheimer model mice

(2010) Anete Rozkalne et al.   NEUROBIOLOGY OF DISEASE

Calcineurin inhibition with systemic FK506 treatment increases dendritic branching and dendritic spine density in healthy adult mouse brain

(2010) Tara L. Spires-Jones et al.   NEUROSCIENCE LETTERS

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

(2009) Giulio Taglialatela et al.   BEHAVIOURAL BRAIN RESEARCH

Evidence for Coregulation of Myocardial Gene Expression by MEF2 and NFAT in Human Heart Failure

(2009) Mary E. Putt et al.   Circulation-Cardiovascular Genetics

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia

(2009) Cindy M Sondag et al.   Journal of Neuroinflammation

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

(2009) H. M. Abdul et al.   JOURNAL OF NEUROSCIENCE

The calcium/NFAT pathway: role in development and function of regulatory T cells

(2009) Masatsugu Oh-hora et al.   MICROBES AND INFECTION

Mechanical lesion activates newly identified NFATc1 in primary astrocytes: implication of ATP and purinergic receptors

(2008) José M. Pérez-Ortiz et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Alternative splicing and expression of human and mouse NFAT genes

(2008) Hanna Vihma et al.   GENOMICS

Calcium/calcineurin signaling in primary cortical astrocyte cultures: Rcan1-4 and cyclooxygenase-2 as NFAT target genes

(2008) Andrea Canellada et al.   GLIA

Interleukin-1β-dependent Signaling between Astrocytes and Neurons Depends Critically on Astrocytic Calcineurin/NFAT Activity

(2008) Michelle A. Sama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of P2X7receptors induces CCL3 production in microglial cells through transcription factor NFAT

(2008) Ayako Kataoka et al.   JOURNAL OF NEUROCHEMISTRY

Deafferentation-Induced Activation of NFAT (Nuclear Factor of Activated T-Cells) in Cochlear Nucleus Neurons during a Developmental Critical Period: A Role for NFATc4-Dependent Apoptosis in the CNS

(2008) J. I. Luoma et al.   JOURNAL OF NEUROSCIENCE

Activation of peroxisome proliferator-activated receptor gamma inhibits endothelin-1-induced cardiac hypertrophy via the calcineurin/NFAT signaling pathway

(2008) Yingxia Bao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON