CD4 + T Cells and Neuroprotection: Relevance to Motoneuron Injury and Disease

SOD1G93A transgenic mouse CD4+ T cells mediate neuroprotection after facial nerve axotomy when removed from a suppressive peripheral microenvironment

(2014) Nichole A. Mesnard-Hoaglin et al.   BRAIN BEHAVIOR AND IMMUNITY

Axotomy-induced target disconnection promotes an additional death mechanism involved in motoneuron degeneration in amyotrophic lateral sclerosis transgenic mice

(2014) Melissa M. Haulcomb et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Immune-mediated Mechanisms in the Pathoprogression of Amyotrophic Lateral Sclerosis

(2013) Weihua Zhao et al.   Journal of Neuroimmune Pharmacology

Systemic Transplantation of Human Umbilical Cord Derived Mesenchymal Stem Cells-Educated T Regulatory Cells Improved the Impaired Cognition in AβPPswe/PS1dE9 Transgenic Mice

(2013) Hongna Yang et al.   PLoS One

Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation

(2013) C Parisi et al.   Cell Death & Disease

A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

(2013) Isaac M. Chiu et al.   Cell Reports

Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival

(2012) Jenny S. Henkel et al.   EMBO Molecular Medicine

Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS

(2012) Bing Liao et al.   EXPERIMENTAL NEUROLOGY

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

(2012) Oleg Butovsky et al.   JOURNAL OF CLINICAL INVESTIGATION

Single session of brief electrical stimulation immediately following crush injury enhances functional recovery of rat facial nerve

(2012) Eileen M. Foecking et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Peripheral nerve inflammation in ALS mice: cause or consequence

(2012) O. Kano et al.   NEUROLOGY

Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis

(2012) Claudia Figueroa-Romero et al.   PLoS One

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

(2011) David R. Beers et al.   BRAIN

Differential gene expression in the axotomized facial motor nucleus of presymptomatic SOD1 mice

(2011) Nichole A. Mesnard et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Abnormal Changes in NKT Cells, the IGF-1 Axis, and Liver Pathology in an Animal Model of ALS

(2011) Arseny Finkelstein et al.   PLoS One

IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection

(2010) Junping Xin et al.   BRAIN BEHAVIOR AND IMMUNITY

Use of laser microdissection in the investigation of facial motoneuron and neuropil molecular phenotypes after peripheral axotomy

(2010) Nichole A. Mesnard et al.   EXPERIMENTAL NEUROLOGY

Regulatory T Cells Attenuate Th17 Cell-Mediated Nigrostriatal Dopaminergic Neurodegeneration in a Model of Parkinson’s Disease

(2010) Ashley D. Reynolds et al.   JOURNAL OF IMMUNOLOGY

Nerve Terminal Degeneration Is Independent of Muscle Fiber Genotype in SOD1G93A Mice

(2010) Dario I. Carrasco et al.   PLoS One

Exacerbation of Facial Motoneuron Loss after Facial Nerve Axotomy in CCR3-Deficient Mice

(2009) Derek A Wainwright et al.   ASN Neuro

Functional recovery and facial motoneuron survival are influenced by immunodeficiency in crush-axotomized mice

(2009) Taylor Beahrs et al.   EXPERIMENTAL NEUROLOGY

Evaluation of humoral immune response in adaptive immunity in ALS patients during disease progression

(2009) Islam A. Saleh et al.   JOURNAL OF NEUROIMMUNOLOGY

Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice

(2009) Derek A. Wainwright et al.   JOURNAL OF NEUROIMMUNOLOGY

Comparison of extratemporal and intratemporal facial nerve injury models

(2009) Nijee Sharma et al.   LARYNGOSCOPE

Is the spinal cord motoneuron exclusively a target in ALS? Comparison between astroglial reactivity in a rat model of familial ALS and in human sporadic ALS cases

(2009) Janina Rafalowska et al.   NEUROLOGICAL RESEARCH

Presymptomatic biochemical changes in hindlimb muscle of G93A human Cu/Zn superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis

(2008) Kevin H.J. Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice

(2008) Rebecca Banerjee et al.   PLoS One

CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS

(2008) D. R. Beers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS

(2008) I. M. Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy

(2007) Junping Xin et al.   BRAIN BEHAVIOR AND IMMUNITY