Article
Engineering, Electrical & Electronic
Rizwan Wahab, Manawwer Alam
Summary: In this study, γ-Al2O3 quantum dots were used as a sensor to detect the organosulfur compound thiourea. The study showed the feasibility and stability of the γ-Al2O3QDs/GCE sensor under different conditions through various experiments and analyses.
SENSORS AND ACTUATORS A-PHYSICAL
(2022)
Article
Chemistry, Medicinal
Takeshi Yokoyama, Mirai Kashihara, Mineyuki Mizuguchi
Summary: The study demonstrates that anthelmintic drugs can effectively inhibit the aggregation of TTR amyloidosis protein, with the potential to be repositioned as inhibitors for ATTR amyloidosis.
JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Naseem Akhtar, Malika Rani, Arshad Mahmood, Kashmala Tariq, G. Murtaza, Asma A. Alothman, Rahaf S. AL-zahrani, Sajid Ali, Naveed Kasuar Janjua, Aqeel Shah
Summary: This work successfully synthesized NaCr2O4/GO nanocomposite using co-precipitation method for energy storage applications. Characterizations such as SEM and XRD were performed to investigate the optical and structural properties. The nanocomposite showed reduced crystalline size and high specific capacitance, making it suitable for various applications.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Chemistry, Inorganic & Nuclear
Rizwan Wahab, Farheen Khan, Manawwer Alam, Javed Ahmad, Abdulaziz A. Al-Khedhairy
Summary: This study designed a sensor material for detecting urea using gamma-Al2O3QDs. The gamma-Al2O3QDs were processed and characterized, and their sensing efficiency with urea solution was tested. The performance of the gamma-Al2O3QDs/GCE sensor was evaluated with different parameters and a real sample analysis was conducted.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Iranna Udachyan, Jayesh T. Bhanushali, Amir Mizrahi, Tomer Zidki, Dan Meyerstein
Summary: This study investigated Mn2(CO3)3/NF as an electrocatalyst for the oxygen evolution reaction, showing lower overpotential and good long-term stability in both KOH and NaHCO3 media.
ACS APPLIED ENERGY MATERIALS
(2022)
Article
Chemistry, Analytical
Hend S. Magar, Ehab E. Abu-El Magd, Rabeay Y. A. Hassan, Asmaa M. Fahim
Summary: A new sensor platform was developed for ultra-trace impedimetric direct detection of cadmium ions in tap water, demonstrating high sensitivity and a wide linear range with a low detection limit.
MICROCHEMICAL JOURNAL
(2022)
Article
Engineering, Electrical & Electronic
Ummama Saeed, Batool Fatima, Dilshad Hussain, Shan E. Zahra Jawad, Muhammad Imran, Muhammad Najam-ul-Haq
Summary: Prostate cancer is a leading cause of mortality, and the PSA test has limitations in its reliability. This study shows that electrochemical sensing using lanthanum tungstate nanoflakes can enhance the accuracy of prostate cancer detection by detecting leucine and valine, which are potential diagnostic biomarkers for prostate cancer.
IEEE SENSORS JOURNAL
(2023)
Article
Energy & Fuels
Wissem Zayani, Samir Azizi, Karam S. El-Nasser, Ibraheem Othman Ali, Michel Moliere, Nouredine Fenineche, Hamadi Mathlouthi, Jilani Lamloumi
Summary: Zinc ferrite spinel alloy synthesized using sol-gel technique was studied for its hydrogen storage properties and applied as an anode in Ni-MH accumulators. Various electromechanical methods were used to examine the hydrogen storage properties, showing good cycling stability. The electrolyte/ZnFe2O4 anode interface was studied using electrochemical impedance spectroscopy before and after activation.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2021)
Article
Chemistry, Inorganic & Nuclear
Magy A. Mekhail, Katherine J. Smith, David M. Freire, Kristof Pota, Nam Nguyen, Marianne E. Burnett, Kayla N. Green
Summary: A series of Cu(II) complexes with different substitutions on the pyridine ring were investigated as superoxide dismutase (SOD) mimics. The modified complexes showed high metal-binding affinities and tuneable redox potentials without changing the coordination environment. The results provide insights for modifying metal complexes using pyridine substitutions in various applications.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Daniel Ejarque, Teresa Calvet, Merce Font-Bardia, Josefina Pons
Summary: Zn(II) complexes with pyridine ligands show improved fluorescence efficiency due to the chelation enhanced effect (CHEF), but steric hindrance also leads to fluorescence quenching.
Article
Biochemistry & Molecular Biology
Pawel Niedzialkowski, Magdalena Bojko, Jacek Ryl, Anna Wcislo, Marta Spodzieja, Katarzyna Magiera-Mularz, Katarzyna Guzik, Grzegorz Dubin, Tad A. Holak, Tadeusz Ossowski, Sylwia Rodziewicz-Motowidlo
Summary: This study successfully demonstrates the modification of a gold electrode with BMS-8 compound for interaction with PD-L1, and further investigates the selectivity of the electrode for other proteins. The work provides a new approach for electrochemical detection of immune checkpoint proteins.
BIOELECTROCHEMISTRY
(2021)
Review
Chemistry, Analytical
Comnea-Stancu Ionela Raluca, Jacobus (Koos) Frederick van Staden, Raluca-Ioana Stefan-van Staden
Summary: This article provides a summary of the recent developments in electrochemical sensors targeting atrazine. It discusses the use of nanoscale materials as electrode modifiers and compares different analytical parameters. The difficulties and opportunities for developing new sensing technology are also explored.
ANALYTICAL LETTERS
(2022)
Review
Chemistry, Analytical
Comnea-Stancu Ionela Raluca, Jacobus (Koos) Frederick van Staden, Raluca-Ioana Stefan-van Staden
Summary: Atrazine, a persistent herbicide, has various harmful effects and its determination is of great importance. This minireview summarizes the recent developments in electrochemical sensors targeting atrazine, using nanoscale materials as electrode modifiers. Analytical parameters are compiled and compared, and future directions for developing new sensing technology are discussed.
ANALYTICAL LETTERS
(2023)
Article
Biotechnology & Applied Microbiology
Bing-Yu Wang, Bien-Chen Gu, Gou-Jen Wang, Yuan-Han Yang, Chia-Che Wu
Summary: This study demonstrates that a nanostructured gold electrode with deposited gold nanoparticles induced via electrochemical impedance spectroscopy (EIS) can be used as a conformation biosensor for the detection of Amyloid-beta(1-42) (A beta(1-42)) oligomers associated with Alzheimer's disease. The concentration of different A beta(1-42) conformations can be determined using EIS analysis with an equivalent circuit model. Probe antibodies (12F4) are used to identify the conformations of A beta(1-42) monomers and oligomers.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Farrukh Bashir Kayani, Saima Rafique, Rizwan Akram, Mozaffar Hussain, Shazia Bashir, Rubina Nasir, Jan Sher Khan
Summary: In this study, an inexpensive and sensitive electrochemical immunosensor was developed using silver/cerium oxide nanocomposites coated with antibody-chitosan as the sensing platform. The developed immunosensor successfully detected alpha-fetoprotein (AFP) in human serum samples. The limit of detection of the immunosensor was calculated to be 0.57 pg.ml(-1).
Article
Biochemical Research Methods
Manna Rachel Mathew, Sanu K. Anand, Jerzy Radecki, Hanna Radecka, K. Girish Kumar
JOURNAL OF FLUORESCENCE
(2020)
Article
Instruments & Instrumentation
Jerzy Radecki, Hanna Radecka
SENSORS AND MATERIALS
(2020)
Article
Chemistry, Analytical
Sanu K. Anand, Manna Rachel Mathew, Jerzy Radecki, Hanna Radecka, K. Girish Kumar
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2020)
Article
Medicine, Legal
Michal Kaliszan, Wojciech Dalewski, Joanna Dawidowska, Tomasz Gos, Zbigniew Jankowski
Summary: This case presents a forensic autopsy of a young woman who was murdered, with her dismembered body hidden in soil and water. Initially thought to be gunshot wounds, the skull injuries were ultimately confirmed to be caused by specialized probes used during the search for the decapitated head. This highlights the importance of comprehensive analysis of all possible causes of injuries during autopsy, particularly in examining the handling of the body prior to being delivered to the morgue to avoid diagnostic errors.
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Gopal Palla, Kamila Malecka, Wim Dehaen, Jerzy Radecki, Hanna Radecka
Summary: This report presents an electrochemical immunosensor for monitoring A beta(1-42) fibrils, fabricated with stepwise assembly of the sensing platform and successfully applied in different media. The immunosensor shows better sensitivity in the presence of APP and moderate response towards A beta(1-42) oligomers, demonstrating good selectivity.
BIOELECTROCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Kamila Malecka, Balwinder Kaur, D. Andrea Cristaldi, Clarissa S. Chay, Iwona Mames, Hanna Radecka, Jerzy Radecki, Eugen Stulz
Summary: A cobalt-porphyrin modified DNA was used as an electrochemical marker to detect specific DNA sequences, comparing the performance of gold and silver nanoparticles in oligonucleotide sensors. Surprisingly, both types of sensors showed similar overall performance, with direct electron transfer between the porphyrin and the electrode. The silver system displayed better DNA economy and cost-effectiveness compared to gold, making it more suitable for mass production of highly sensitive DNA sensors.
BIOELECTROCHEMISTRY
(2021)
Article
Chemistry, Analytical
Daria Rudewicz-Kowalczyk, Iwona Grabowska
Summary: This study compared the characteristics of an immunosensor and an aptasensor for detecting LDL, finding that the aptasensor exhibited better selectivity towards HSA, HDL, and MDA-LDL, with no interference from other components of serum samples.
Review
Chemistry, Analytical
Iwona Grabowska, Maria Hepel, Katarzyna Kurzatkowska-Adaszynska
Summary: In recent years, the development of biosensor technology has been accelerated by the increasing demand for simple, fast, and cost-effective detection of food and environmental contaminants, as well as the need for monitoring biomarkers of different diseases. However, simultaneous determination of multiple analytes in a single measurement using biosensors is still a major challenge. Electrochemical aptasensors, combining the high sensitivity and scalability of electrochemical detection systems with the specificity of aptamers, are considered highly effective devices for simultaneous detection of multiple-target analytes. This review focuses on multi-label approaches based on metal quantum dots and ions, redox labels, and enzyme labels, and highlights the use of different nanomaterials in the construction of these aptasensors. The review also discusses the recent applications of multiplexed detection platforms in clinical diagnostics, food control, and environmental monitoring, and addresses the advantages, disadvantages, challenges, and prospects of the developed aptasensors.
Article
Biochemistry & Molecular Biology
Kamila Malecka-Baturo, Apostolos Zaganiaris, Iwona Grabowska, Katarzyna Kurzatkowska-Adaszynska
Summary: In this paper, an electrochemical platform based on ssDNA aptamer for the detection of tetracycline in food products has been proposed. The developed biosensor shows simplicity, low detection limit, and high reliability, and has been successfully applied to the detection of tetracycline in cow milk.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Medicine, Legal
Karol Karnecki, Adrian Wroclawski, Dorota Piesniak, Wojciech Dalewski, Tomasz Gos, Michal Kaliszan
Summary: The study analyzed 107 medicolegal autopsies of homicide victims from 2010-2019 in Poland, focusing on homicide mechanisms, weapon types, injuries characteristics, and causes of death. The study found that males accounted for 70.1% of the analyzed cases, with blunt instruments as the most frequently used weapon (47.7% of cases). Fatal head injuries were the predominant cause of death (32.7% of cases).
JOURNAL OF FORENSIC AND LEGAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Daria Rudewicz-Kowalczyk, Iwona Grabowska
Summary: This study presents magnetic beads-based immunosensors for simultaneous detection of low density lipoprotein (LDL) and malondialdehyde-modified low density lipoprotein (MDA-LDL). The proposed approach involves the use of specific immunoconjugates and redox active molecules coated on magnetic beads to detect the target biomarkers. The method showed good selectivity, stability, and recovery, indicating its potential for early diagnosis and prognosis of ACSVD.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Dania Rudewicz-Kowalczyk, Iwona Grabowska
Summary: An electrochemical platform for fast and accurate detection of LDL based on an antibody-ferrocene conjugate was developed in this study. The method linearly detected LDL concentration in the range of 0.01 ng/mL to 1.0 ng/mL, with a detection limit of 0.53 ng/mL, and showed selectivity towards other substances. This suggests the potential application of the immunosensors in clinical diagnostics.