Recent Insights into the Pathobiology of Innate Immune Deficiencies

A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans

(2011) Hye Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

(2010) I. Isnardi et al.   BLOOD

Lentiviral vectors incorporating a human elongation factor 1α promoter for the treatment of canine leukocyte adhesion deficiency

(2010) E J R Nelson et al.   GENE THERAPY

Leukocyte Adhesion Deficiency Type II: Long-Term Follow-Up and Review of the Literature

(2010) Yael Gazit et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease

(2010) Douglas B. Kuhns et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions

(2009) E. Manevich-Mendelson et al.   BLOOD

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

(2009) J. D. Matute et al.   BLOOD

Hidden talents of natural killers: NK cells in innate and adaptive immunity

(2009) Megan A. Cooper et al.   EMBO REPORTS

Clearing the AIRE: On the Pathophysiological Basis of the Autoimmune Polyendocrinopathy Syndrome Type-1

(2009) Noriko Shikama et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

NKT cells: Friend or foe during viral infections?

(2009) Julien Diana et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Natural killer cells remember: An evolutionary bridge between innate and adaptive immunity?

(2009) Joseph C. Sun et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-α/β, IFN-γ, and IFN-λ in host defense

(2009) Shen-Ying Zhang et al.   IMMUNOLOGICAL REVIEWS

Neutropenia and Primary Immunodeficiency Diseases

(2009) Nima Rezaei et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Statewide Newborn Screening for Severe T-Cell Lymphopenia

(2009) John M. Routes   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Girls homozygous for an IL-2–inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

(2009) Kirsten Huck et al.   JOURNAL OF CLINICAL INVESTIGATION

A partial form of recessive STAT1 deficiency in humans

(2009) Ariane Chapgier et al.   JOURNAL OF CLINICAL INVESTIGATION

The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function

(2009) Michela Locci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Uncoupling CD21 and CD19 of the B-cell coreceptor

(2009) R. A. Barrington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

(2009) M. Rakhmanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in understanding of pathogenesis of aHUS and HELLP

(2008) Celia J. Fang et al.   BRITISH JOURNAL OF HAEMATOLOGY

ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease

(2008) Kelly L. Brown et al.   CLINICAL IMMUNOLOGY

Carriers of X-linked chronic granulomatous disease at risk

(2008) Joachim Roesler   CLINICAL IMMUNOLOGY

WHIM syndrome: congenital immune deficiency disease

(2008) Toshinao Kawai et al.   CURRENT OPINION IN HEMATOLOGY

Dysregulation of innate immune receptors on neutrophils in chronic granulomatous disease

(2008) Dominik Hartl et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity

(2008) Eric P. Hanson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory Manifestations in Chronic Granulomatous Disease (CGD)

(2008) S. D. Rosenzweig   JOURNAL OF CLINICAL IMMUNOLOGY

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

(2008) Luigina Romani et al.   NATURE

Complement Regulatory Genes and Hemolytic Uremic Syndromes

(2007) David Kavanagh et al.   Annual Review of Medicine