Cryopyrin-Associated Periodic Syndrome: An Update on Diagnosis and Treatment Response

Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

(2010) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study

(2010) Alexander So et al.   ARTHRITIS AND RHEUMATISM

A somatic NLRP3 mutation as a cause of a sporadic case of chronic infantile neurologic, cutaneous, articular syndrome/neonatal-onset multisystem inflammatory disease: Novel evidence of the role of low-level mosaicism as the pathophysiologic mechanism unde

(2010) Juan I. Aróstegui et al.   ARTHRITIS AND RHEUMATISM

Monogenic IL-1 mediated autoinflammatory and immunodeficiency syndromes: Finding the right balance in response to danger signals

(2010) Cailin Henderson et al.   CLINICAL IMMUNOLOGY

Modern Approaches to the Diagnosis and Treatment of Cold Contact Urticaria

(2010) Karoline Krause et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Otolaryngological manifestations of ‘Muckle–Wells syndrome’

(2010) Deb Biswas et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

A case of refractory adult-onset Still’s disease treated with anakinra

(2010) Manjari LAHIRI et al.   International Journal of Rheumatic Diseases

Persistent pruritic papules and plaques: a characteristic histopathologic presentation seen in a subset of patients with adult-onset and juvenile Still's disease

(2010) Ryan R. Fortna et al.   JOURNAL OF CUTANEOUS PATHOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1  secretion

(2010) S. Tassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rilonacept-CAPS and Beyond

(2009) Neil Stahl et al.   Annals of the New York Academy of Sciences

The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study

(2009) R Terkeltaub et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-term efficacy of the interleukin-1 receptor antagonist anakinra in ten patients with neonatal-onset multisystem inflammatory disease/chronic infantile neurologic, cutaneous, articular syndrome

(2009) Bénédicte Neven et al.   ARTHRITIS AND RHEUMATISM

Targeted treatment of pyoderma gangrenosum in PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra

(2009) M. Brenner et al.   BRITISH JOURNAL OF DERMATOLOGY

Schnitzler’s syndrome with prominent neutrophil infiltration misdiagnosed as Sweet’s syndrome: a typical example of urticarial neutrophilic dermatosis

(2009) A. Asahina et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Neurological manifestations of the Mendelian-inherited autoinflammatory syndromes

(2009) GINA A MONTEALEGRE SANCHEZ et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Interleukin-1 beta targeted therapy for type 2 diabetes

(2009) Kathrin Maedler et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Autoinflammation: The prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses

(2009) Raphaela Goldbach-Mansky et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes

(2009) Helen J. Lachmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist

(2009) Ivona Aksentijevich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome

(2009) Helen J. Lachmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

An Autoinflammatory Disease Due to Homozygous Deletion of theIL1RNLocus

(2009) Sreelatha Reddy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cerebrospinal Fluid Neopterin and Cryopyrin-Associated Periodic Syndrome

(2009) Mercedes Serrano et al.   PEDIATRIC NEUROLOGY

A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 trap) in patients with familial cold autoinflammatory syndrome

(2008) Raphaela Goldbach-Mansky et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of rilonacept (interleukin-1 trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies

(2008) Hal M. Hoffman et al.   ARTHRITIS AND RHEUMATISM

Cryopyrin-associated periodic syndromes: development of a patient-reported outcomes instrument to assess the pattern and severity of clinical disease activity

(2008) Hal M. Hoffman et al.   CURRENT MEDICAL RESEARCH AND OPINION

Familial cold auto-inflammatory syndrome (FCAS): characterization of symptomatology and impact on patients' lives

(2008) Beate Stych et al.   CURRENT MEDICAL RESEARCH AND OPINION

NLR, the nucleotide-binding domain leucine-rich repeat containing gene family

(2008) Zhengmao Ye et al.   CURRENT OPINION IN IMMUNOLOGY

Schnitzler syndrome

(2008) Martin Soubrier   JOINT BONE SPINE

Developments in the scientific and clinical understanding of gout

(2008) Alexander So   ARTHRITIS RESEARCH & THERAPY

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

(2008) Rieke Alten et al.   ARTHRITIS RESEARCH & THERAPY