Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells

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Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS

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Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes

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Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis

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Specific Induction of Akt3 in Spinal Cord Motor Neurons is Neuroprotective in a Mouse Model of Familial Amyotrophic Lateral Sclerosis

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The changing scene of amyotrophic lateral sclerosis

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Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

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Intricate interplay between astrocytes and motor neurons in ALS

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Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis

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Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival

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Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons

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Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

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The Role of Immune and Inflammatory Mechanisms in ALS

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TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

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Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord

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Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice

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Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice

(2009) Chiara Pizzasegola et al.   Amyotrophic Lateral Sclerosis

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Isolation and enrichment of embryonic mouse motoneurons from the lumbar spinal cord of individual mouse embryos

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Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis†

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TNF and sTNFR1/2 plasma levels in ALS patients

(2008) Cristina Cereda et al.   JOURNAL OF NEUROIMMUNOLOGY

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

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Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice

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Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels

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